Listar Artículos (Química Orgánica) por título
Mostrando ítems 208-227 de 263
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Stereoselective synthesis of chiral furan amino acid analogues of D- and L-serine from D-sugars
(Georg Thieme Verlag, 2006)The synthesis of chiral furan amino acid analogues of D - and L -serine is reported. The developed methodology ...
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Stereoselective Synthesis of Iminosugar 2-Deoxy(thio)glycosides from Bicyclic Iminoglycal Carbamates Promoted by Cerium(IV) Ammonium Nitrate and Cooperative Brønsted Acid-Type Organocatalysis
(American Chemical Society, 2020)The first examples of iminosugar-type 2-deoxy(thio)glycoside mimetics are reported. The key step is the activation of a ...
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Stereoselective Synthesis of Nojirimycin α-C-Glycosides from a Bicyclic Acyliminium Intermediate: A Convenient Entry to N,C-Biantennary Glycomimetics
(American Chemical Society, 2022)A simple and efficient method for the stereoselective synthesis of nojirimycin α-C-glycoside derivatives has been developed ...
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Strongly Emissive and Photostable Four-Coordinate Organoboron N,C Chelates and Their Use in Fluorescence Microscopy
(Wiley-Blackwell, 2015)Six strongly fluorescent four-coordinate organoboron N,C chelates containing an aryl isoquinoline skeleton were prepared. ...
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Structural basis of pharmacological chaperoning for human β-galactosidase
(Elsevier, 2014)GM1 gangliosidosis and Morquio B disease are autosomal recessive diseases caused by the defect in the lysosomal β-galactosidase ...
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Structural Basis of the Inhibition of GH1 β-glucosidases by Multivalent Pyrrolidine Iminosugars
(Elsevier, 2019)The synthesis of multivalent pyrrolidine iminosugars via CuAAC click reaction between different pyrrolidine-azide derivatives ...
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Structural basis of trehalose recognition by the mycobacterial LpqY-SugABC transporter
(American Society for Biochemistry and Molecular Biology Inc., 2021)The Mycobacterium tuberculosis (Mtb) LpqY-SugABC ATPbinding cassette transporter is a recycling system that imports trehalose ...
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Structure and biological roles of Sinorhizobium fredii HH103 exopolysaccharide
(Public Library of Science, 2014)Here we report that the structure of the Sinorhizobium fredii HH103 exopolysaccharide (EPS) is composed of glucose, ...
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Structure of the unusual Sinorhizobium fredii HH103 lipopolysaccharide and its role in symbiosis
(Elsevier, 2020)Rhizobia are soil bacteria that form important symbiotic associations with legumes, and rhizobial surface polysaccharides, ...
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Structure-Based Identification and Biological Characterization of New NAPRT Inhibitors
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)NAPRT, the rate-limiting enzyme of the Preiss–Handler NAD biosynthetic pathway, has emerged as a key biomarker for the ...
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Studies on the Synthesis of 2-Alkyl-5-aryl-1,3,4-oxadiazolines from N-Acylhydrazones
(2012)Reaction of N-acylhydrazones with benzyloxyacetyl chloride in the presence of i-Pr 2EtN affords new 1,3,4-oxadiazolines ...
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Syntheses and biological activities of 1,4-iminoalditol derivatives as α-L-fucosidase inhibitors
(Schweizerische Chemische Gesellschaft (Swiss Chemistry Society), 2011)A review dealing with 1,4-iminoalditol (hydroxylated pyrrolidine) derivatives as inhibitors of α-l-fucosidases including the different synthetic approaches for their preparation as well as their inhibitory properties is presented.
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Synthesis and Antiproliferative Activity of Sulfa-Michael Adducts and Thiochromenes Derived from Carbohydrates
(Royal Society of Chemistry, 2017)The Michael addition reactions of carbohydrate-derived nitroalkenes with ethyl thioglycolate and 2-mercaptobenzyl alcohol ...
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Synthesis and Biological Evaluation of Modified 2-Deoxystreptamine Dimers
(Thieme Publishing; Georg Thieme Verlag, 2011)Aminoglycosides are powerful antibiotics, but the emergence of resistant bacterial strains has prompted the search for ...
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Synthesis and cancer growth inhibitory activities of 2-fatty-alkylated pyrrolidine-3,4-diol derivatives
(Arkat USA, 2014)A series of new amphiphilic pyrrolidines containing dodecyl and oleyl apolar side chains were prepared and evaluated for ...
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Synthesis and Structure-activity Relationship of New Nicotinamide Phosphoribosyltransferase Inhibitors with Antitumor Activity on Solid and Haematological Cancer
(Elsevier, 2023)Cancer cells are highly dependent on Nicotinamide phosphoribosyltransferase (NAMPT) activity for proliferation, therefore ...
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Synthesis of axially chiral heterobiaryl alkynes via dynamic kinetic asymmetric alkynylation
(Wiley, 2016)The dynamic kinetic Pd0 -catalyzed alkynylation of racemic heterobiaryl sulfonates was used for the asymmetric synthesis ...
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Synthesis of hyperpolarizable biomaterials at molecular level based on pyridinium-chitosan complexes
(Universidade Federal do Espírito Santo, 2015)Potential NLO-phore materials based on chitosan are described for the first time in this study. A series of fluorescent ...