Browsing Artículos (Química Orgánica) by Title
Now showing items 1-20 of 215
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1,4-Dideoxy-1,4-imino-d-arabinitol (DAB) Analogues Possessing a Hydrazide Imide Moiety as Potent and Selective α-Mannosidase Inhibitors
(American Chemical Society, 2020)The synthesis of two polyhydroxylated pyrrolidines as 1,4-dideoxy-1,4-imino-d-arabinitol (DAB) analogues bearing a hydrazide ...
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2-Aminobenzoxazole-appended coumarins as potent and selective inhibitors of tumour-associated carbonic anhydrases
(Taylor & Francis, 2022)We have carried out the design, synthesis, and evaluation of a small library of 2-aminobenzoxazole-appended coumarins as ...
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25th Anniversary of Molecules—Recent Advances in Green Chemistry
(Multidisciplinary Digital Publishing Institute (MDPI), 2021) -
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A Bicyclic 1-Deoxygalactonojirimycin Derivative as a Novel Pharmacological Chaperone for GM1 Gangliosidosis
(Cell Press, 2013)Lysosomal β-galactosidase (β-Gal) deficiency causes a group of disorders that include neuronopathic GM1 gangliosidosis and ...
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A broadened scope for the use of hydrazones as neutral nucleophiles in the presence of H-bonding organocatalysts
(2006)Using thioureas as H-bonding organocatalysts, nitroalkenes can be activated for the conjugate addition of hydrazones as ...
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A Dynamic Kinetic Asymmetric Heck Reaction for the Simultaneous Generation of Central and Axial Chirality
(American Chemical Society, 2018)A highly diastereo- and enantioselective, scalable Pd-catalyzed dynamic kinetic asymmetric Heck reaction of heterobiaryl ...
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A gliclazide complex based on palladium towards Alzheimer's disease: promising protective activity against Aβ-induced toxicity in C. elegans
(Royal Society of Chemistry, 2022)A new palladium coordination compound based on gliclazide with the chemical formula [Pd(glz)2] (where glz = gliclazide) ...
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A novel approach to the synthesis of N-substituted 1-C-aminomethyl glycofuranosides
(2006)Reductive amination of formyl C-glycofuranosides, easily available from hexose-derived equatorial-2-OH-glycopyranosides by DAST-promoted ring contraction, afforded N-substituted 1-C-aminomethyl glycofuranosides in most cases in high yield.
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A Practical Synthesis of Enantiopure 4,5-Dihydroisoxazole-5-carboxylic Acids
(2005)The 1,3-dipolar cycloaddition of a variety of aromatic and aliphatic nitrile oxides to 2,5-trans-2,5-diphenylpyrrolidine ...
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A versatile stereocontrolled synthesis of 2-deoxyiminosugarC-glycosides and their evaluation as glycosidase inhibitors
(Royal Society of Chemistry, 2021)A highly enantioselective synthesis of (R,S) or (S,S)-2,6-disubstituted dehydropiperidines has been previously achieved ...
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A β-Cyclodextrin-Based Nanoparticle with Very High Transfection Efficiency Unveils siRNA-Activated TLR3 Responses in Human Prostate Cancer Cells
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)Synthetic double-stranded small interfering RNAs (siRNAs) mimic interference RNAs (RNAi) and can bind target mRNAs with a ...
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Alkoxyamine-cyanoborane adducts: Efficient cyanoborane transfer agents
(Royal Society of Chemistry, 2011)We report the synthesis of the hitherto unknown zwitterionic alkoxyamino cyanoboranes by reduction of O-alkyloximes with ...
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Ambiphilic boryl groups in a neutral Ni(ii) complex: a new activation mode of H2
(Royal Society of Chemistry, 2021)The concept of metal–ligand cooperation opens new avenues for the design of catalytic systems that may offer alternative ...
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Analysis of the lipid moiety of lipopolysaccharide from Rhizobium tropici CIAT899: identification of 29-hydroxytriacontanoic acid
(American Society for Microbiology, 1994)The lipid moieties of two lipid A's isolated from the phenolic and aqueous fractions of lipopolysaccharide from Rhizobium ...
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Anti-Inflammatory (M2) Response Is Induced by a sp2-Iminosugar Glycolipid Sulfoxide in Diabetic Retinopathy
(Frontiers, 2021)Diabetic retinopathy (DR) is one of the most common complications of Diabetes Mellitus (DM) and is directly associated ...
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Application of Biobased Solvents in Asymmetric Catalysis
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)The necessity of more sustainable conditions that follow the twelve principles of Green Chemistry have pushed researchers ...
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Arylisoquinoline-derived organoboron dyes with a triaryl skeleton show dual fluorescence
(Beilstein-Institut, 2019)Se prepararon cuatro nuevos colorantes que derivan de arilisoquinolinas boryiladas, que contienen un tercer residuo de ...
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Asymmetric Organocatalytic Synthesis of Fluorinated β-Hydroxy Diazenes
(Wiley-Blackwell, 2019)The nucleophilic addition of formaldehyde tert-butyl hydrazone to fluoromethyl ketones provides a valuable tool for the ...
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Asymmetric synthesis of dibenzo[b,d]azepines by Cu-catalyzed reductive or borylative cyclization
(Royal Society of Chemistry, 2021)A copper-catalyzed asymmetric intramolecular reductive cyclization for the synthesis of dibenzo[b,d]azepines is described. ...