Química Orgánica
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Artículo
Evolution of the catalytic mechanism at the dawn of the Baeyer-Villiger monooxygenases
(Elsevier, 2024-05-28)Enzymes are crucial for the emergence and sustenance of life on earth. How they became catalytically active during their ...
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sp2-Iminosugar Azobenzene O-glycosides: Light-sensitive Glycosidase Inhibitors with Unprecedented Tunability and Switching Factors
(Elsevier, 2024)The conventional approach to developing light-sensitive glycosidase activity regulators, involving the combination of a ...
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Speeding-up the Determination of Protein-Ligand Affinities by STD NMR: The Reduced Data Set STD NMR Approach (rd-STD NMR)
(American Chemical Society, 2024-01-02)STD NMR spectroscopy is a powerful ligand-observed NMR tool for screening and characterizing the interactions of small ...
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Mechanically Planar-to-Point Chirality Transmission in [2]Rotaxanes
(American Chemical Society, 2024-01-24)Herein we describe an effective transmission of chirality, from mechanically planar chirality to point chirality, in ...
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High-Mannose Oligosaccharide Hemimimetics that Recapitulate the Conformation and Binding Mode to Concanavalin A, DC-SIGN and Langerin
(Wiley, 2023-10-12)The “carbohydrate chemical mimicry” exhibited by sp2-iminosugars has been utilized to develop practical syntheses for ...
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Coumarins-lipophilic cations conjugates: Efficient mitocans targeting carbonic anhydrases
(Elsevier, 2024-02-13)Being aware of the need to develop more efficient therapies against cancer, herein we disclose an innovative approach for ...
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Atroposelective Synthesis of 2-(Quinolin-8-yl)benzyl Alcohols by Biocatalytic Dynamic Kinetic Resolutions
(Wiley, 2023-12-22)A highly enantioselective biocatalytic dynamic kinetic resolution (DKR) of 2-(quinoline-8-yl) 3-methylbenzaldehydes and ...
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Divergent approach to nanoscale glycomicelles and photo-responsive supramolecular glycogels. Implications for drug delivery and photoswitching lectin affinity
(Royal Society of Chemistry, 2023-10-09)The field of stimuli-responsive supramolecular biomaterials has rapidly advanced in recent years, with potential applications ...
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Tesis Doctoral
Caracterización química de ligninas y lípidos de cultivos y residuos agrícolas
(2024-04-05)La presente Tesis Doctoral aborda la caracterización química de las ligninas y los lípidos presentes en diversos materiales ...
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Continuous flow synthesis of PCN-222 (MOF-545) with controlled size and morphology: a sustainable approach for efficient production
(Royal Society of Chemistry, 2023-11-21)Zirconium-based MOFs, such as PCN-222 (MOF-545), have gained attention due to their regular porosity, tuneable pore size, ...
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Capítulo de Libro
La implicación del alumnado como fuerza motriz en el desarrollo de la asignatura Experimentación en Química II
(Universidad de Sevilla, 2023)El ciclo de mejora aplicado en la asignatura Experimentación en Química II del Grado en Ingeniería Química Industrial ...
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Capítulo de Libro
¿Cómo enseñar Química Orgánica?
(Universidad de Sevilla, 2023)La asignatura de Química Orgánica del grado de Bioquímica es de nuevo la asignatura elegida para el ciclo de mejora al ...
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Capítulo de Libro
Exploración de la combinación de diferentes herramientas didácticas sobre el aprendizaje activo del alumnado
(Universidad de Sevilla, 2023)El Ciclo de Mejora en el Aula planteado para el curso académico 2022-2023 se ha llevado a cabo en la asignatura obligatoria ...
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Artículo
Silver-free gold-catalyzed heterocyclizations through intermolecular H-bonding activation.
(AMER Chemical Soc, 2023-01-27)Modulable monosulfonyl squaramides have been shown to exert activation of gold(I) chloride complexes through H-bonding in ...
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Artículo
N-Substituted 3-Aminooxindoles and N-Propargyl Derivatives: Potential Biological Activities against Alzheimer's Disease
(Elsevier, 2023-07-08)The oxindole core is an important structural motif in many natural and synthetic substances with various biological ...
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Multivalent glycosystems for human lectins
(Royal Society of Chemistry, 2022-08-30)Human lectins are involved in a wide variety of biological processes, both physiological and pathological, which have ...
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Green Oxidative Catalytic Processes for the Preparation of APIs and Precursors
(MDPI, 2023-03-22)Asymmetric oxidation processes have constituted a valuable tool for the synthesis of active pharmaceutical ingredients ...
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Excited-state dynamics in borylated arylisoquinoline complexes in solution and in cellulo
(Wiley-V C H Verlag GMBH, 2022-12-07)Two four-coordinate organoboron N,C-chelate complexes with different functional terminals on the PEG chains are studied ...
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Artículo
Dynamic Kinetic Resolution of Indole-Based Sulfenylated Heterobiaryls by Rhodium-Catalyzed Atroposelective Reductive Aldol Reaction
(Amer chemical SOC, 2023-08-30)A highly enantio- and diastereoselective dynamic kinetic resolution (DKR) of configurationally labile 3-aryl indole-2-carbaldehydes ...