• Article
  

  Studies on the Regioselective Rearrangement of Azanorbornanic Aminyl Radicals into 2,8-Diazabicyclo[3.2.1]oct-2-ene Systems 

  Gil de Montes Rojas, Enrique; Tallarida, Matteo A.; Carmona Asenjo, Ana Teresa; Navo, Claudio D.; Robina Ramírez, Inmaculada; Elías Rodríguez, María del Pilar; Jiménez Oses, Gonzalo; Moreno Vargas, Antonio José (American Chemical Society, 2022)

  Aminyl radicals are nitrogen-centered radicals of interest in synthetic strategies involving C–N bond formation due to ...

• Article
  

  Pd(II)-Catalyzed Asymmetric Addition of Arylboronic Acids to Aliphatic N-Carbamoyl Hydrazones 

  Alberca Manzano, Saúl; Velázquez Muñoz, Marta; Trujillo Sierra, José; Iglesias Sigüenza, Francisco Javier; Fernández Fernández, Rosario Fátima; Lassaletta, José M.; Monge Fernández, David (Wiley, 2022)

  Catalysts generated by combinations of Pd(TFA)2 and pyridine-hydrazone ligands have been applied to 1,2 addition of ...

• Article
  

  Asymmetric Synthesis of Axially Chiral C N Atropisomers 

  Rodríguez Salamanca, Patricia; Fernández Fernández, Rosario Fátima; Hornillos, Valentín; Lassaletta, José M. (Wiley, 2022)

  Molecules with restricted rotation around a single bond or atropisomers are found in a wide number of natural products ...

• Presentation
  

  Aprendizaje basado en problemas para la enseñanza de la química en la universidad 

  Maya Díaz, Celia María; Iglesias Sigüenza, Francisco Javier (2019)

  El objetivo del trabajo es analizar la eficacia de la metodología del aprendizaje basado en problemas (ABP) en una titulación ...

• Article
  

  Evolution of the catalytic mechanism at the dawn of the Baeyer-Villiger monooxygenases 

  Yang, Guang; Pećanac, Ognjen; Wijma, Hein J.; Rozeboom, Henriëtte J.; Gonzalo Calvo, Gonzalo de; Fraaije, Marco W.; Mascotti, Maria Laura (Elsevier, 2024-05-28)

  Enzymes are crucial for the emergence and sustenance of life on earth. How they became catalytically active during their ...

• Article
  

  sp2-Iminosugar Azobenzene O-glycosides: Light-sensitive Glycosidase Inhibitors with Unprecedented Tunability and Switching Factors 

  Rivero Barbarroja, Gonzalo; Padilla Pérez, María del Carmen; Maisonneuve, Stéphane; García Moreno, M. Isabel; Tiet, Ben; Vocadlo, David J.; Xie, Juan; García Fernández, José M.; Ortiz Mellet, Carmen (Elsevier, 2024)

  The conventional approach to developing light-sensitive glycosidase activity regulators, involving the combination of a ...

• Article
  

  Speeding-up the Determination of Protein-Ligand Affinities by STD NMR: The Reduced Data Set STD NMR Approach (rd-STD NMR) 

  Rocha, Gabriel; Ramírez Cárdenas, Jonathan; Padilla Pérez, María del Carmen; Walpole, Samuel; Nepravishta, Ridvan; García Moreno, M. Isabel; Sánchez Fernández, Elena Matilde; Ortiz Mellet, Carmen; Angulo, Jesús; Muñoz García, Juan Carlos (American Chemical Society, 2024-01-02)

  STD NMR spectroscopy is a powerful ligand-observed NMR tool for screening and characterizing the interactions of small ...

• Article
  

  Mechanically Planar-to-Point Chirality Transmission in [2]Rotaxanes 

  Puigcerver, Julio; Marín Luna, Marta; Iglesias Sigüenza, Francisco Javier; Alajarin, Mateo; Martinez-Cuezva, Alberto; Berna, Jose (American Chemical Society, 2024-01-24)

  Herein we describe an effective transmission of chirality, from mechanically planar chirality to point chirality, in ...

• Article
  

  High-Mannose Oligosaccharide Hemimimetics that Recapitulate the Conformation and Binding Mode to Concanavalin A, DC-SIGN and Langerin 

  Herrera González, Irene; González Cuesta, Manuel; Thépaut, Michel; Laigre, Eugénie; Goyard, David; Rojo, Javier; García Fernández, José Manuel; Ortiz Mellet, Carmen (Wiley, 2023-10-12)

  The “carbohydrate chemical mimicry” exhibited by sp2-iminosugars has been utilized to develop practical syntheses for ...

• Article
  

  Coumarins-lipophilic cations conjugates: Efficient mitocans targeting carbonic anhydrases 

  Fuentes Aguilar, Alma; González-Bakker, Aday; Jovanović, Mirna; Stojanov, Sofija Jovanović; Puerta, Adrián; Gargano, Adriana; Fernández-Bolaños Guzmán, José María; López López, Óscar (Elsevier, 2024-02-13)

  Being aware of the need to develop more efficient therapies against cancer, herein we disclose an innovative approach for ...

• Article
  

  Atroposelective Synthesis of 2-(Quinolin-8-yl)benzyl Alcohols by Biocatalytic Dynamic Kinetic Resolutions 

  Coto Cid, Juan Manuel; Gonzalo Calvo, Gonzalo de; Carmona, José A.; Iglesias Sigüenza, Francisco Javier; Rodríguez Salamanca, Patricia; Fernández Fernández, Rosario Fátima; Hornillos, Valentín; Lassaletta, José M. (Wiley, 2023-12-22)

  A highly enantioselective biocatalytic dynamic kinetic resolution (DKR) of 2-(quinoline-8-yl) 3-methylbenzaldehydes and ...

• Article
  

  Divergent approach to nanoscale glycomicelles and photo-responsive supramolecular glycogels. Implications for drug delivery and photoswitching lectin affinity 

  Romero Ben, Elena; Castillejos Anguiano, María del Carmen; Rosales Barrios, Cristian; Expósito, María; Ruda, Pilar; Castillo, Paula M.; Khiar, Noureddine (Royal Society of Chemistry, 2023-10-09)

  The field of stimuli-responsive supramolecular biomaterials has rapidly advanced in recent years, with potential applications ...

• PhD Thesis
  

  Caracterización química de ligninas y lípidos de cultivos y residuos agrícolas 

  Rosado Rodríguez, Mario Jesús (2024-04-05)

  La presente Tesis Doctoral aborda la caracterización química de las ligninas y los lípidos presentes en diversos materiales ...

• Article
  

  Continuous flow synthesis of PCN-222 (MOF-545) with controlled size and morphology: a sustainable approach for efficient production 

  Zuliani, A; Castillejos Anguiano, María del Carmen; Khiar, Noureddine (Royal Society of Chemistry, 2023-11-21)

  Zirconium-based MOFs, such as PCN-222 (MOF-545), have gained attention due to their regular porosity, tuneable pore size, ...

• Chapter of Book
  

  Innovación docente en las prácticas de laboratorio de genética: clase invertida y pensamiento crítico 

  Castellano Pozo, Maikel; Iglesias Sigüenza, Francisco Javier; Comaills, Valentine; Valle Rosado, Iván (Dykinson, 2023)
• Chapter of Book
  

  La implicación del alumnado como fuerza motriz en el desarrollo de la asignatura Experimentación en Química II 

  Sánchez Fernández, Elena Matilde (Universidad de Sevilla, 2023)

  El ciclo de mejora aplicado en la asignatura Experimentación en Química II del Grado en Ingeniería Química Industrial ...

• Chapter of Book
  

  ¿Cómo enseñar Química Orgánica? 

  Vázquez Cabello, Juan (Universidad de Sevilla, 2023)

  La asignatura de Química Orgánica del grado de Bioquímica es de nuevo la asignatura elegida para el ciclo de mejora al ...

• Chapter of Book
  

  Exploración de la combinación de diferentes herramientas didácticas sobre el aprendizaje activo del alumnado 

  Sánchez Fernández, Elena Matilde (Universidad de Sevilla, 2023)

  El Ciclo de Mejora en el Aula planteado para el curso académico 2022-2023 se ha llevado a cabo en la asignatura obligatoria ...

• Article
  

  Silver-free gold-catalyzed heterocyclizations through intermolecular H-bonding activation. 

  Elías Rodríguez, María del Pilar; Matador Martínez, Esteban; Benítez Narváez, Manuel; Tejero, Tomás; Díez Martín, Elena; Fernández Fernández, Rosario Fátima; Monge Fernández, David; Lassaletta, José M. (AMER Chemical Soc, 2023-01-27)

  Modulable monosulfonyl squaramides have been shown to exert activation of gold(I) chloride complexes through H-bonding in ...

• Article
  

  N-Substituted 3-Aminooxindoles and N-Propargyl Derivatives: Potential Biological Activities against Alzheimer's Disease 

  Hofmanova, Tereza; Marques, Carolina; García-Sosa, Alfonso T.; López López, Óscar; Leitzbach, Luisa; Carreiro, Elisabete P.; Fernández-Bolaños Guzmán, José María; Burke, Anthony J. (Elsevier, 2023-07-08)

  The oxindole core is an important structural motif in many natural and synthetic substances with various biological ...

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