Listar Artículos (Química Orgánica) por título
Mostrando ítems 243-262 de 267
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Tackling Antibiotic Resistance: Influence of Aliphatic Branches on Broad-Spectrum Antibacterial Polytriazoles against ESKAPE Group Pathogens
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)One of the most important threats to public health is the appearance of multidrug-resistant pathogenic bacteria, since ...
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Tacrine-O-protected phenolics heterodimers as multitarget-directed ligands against Alzheimer's disease: Selective subnanomolar BuChE inhibitors
(Elsevier, 2019-11-01)Concerned by the devastating effects of Alzheimer's disease, and the lack of effective drugs, we have carried out the ...
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Tacrine-sugar mimetic conjugates as enhanced cholinesterase inhibitors
(Royal Society of Chemistry, 2021-03-14)We have used the Cu(i)-catalyzed azide-alkyne Huisgen cycloaddition reaction to obtain two families of bivalent heterodimers ...
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The nodulation of Alfalfa by the acid-tolerant Rhizobium sp. Strain LPU83 does not require sulfated forms of Lipochitooligosaccharide nodulation signals
(American Society for Microbiology, 2011)The induction of root nodules by the majority of rhizobia has a strict requirement for the secretion of symbiosis-specific ...
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The Role of Two Linear β-Glucans Activated by c-di-GMP in Rhizobium etli CFN42
(MDPI, 2022)Bacterial exopolysaccharides (EPS) are secreted biopolymers with often critical roles in bacterial physiology and ecology. ...
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Thio- and selenosemicarbazones as antiprotozoal agents against Trypanosoma cruzi and Trichomonas vaginalis
(Taylor & Francis, 2022)Herein, we report the preparation of a panel of Schiff bases analogues as antiprotozoal agents by modification of the ...
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Thiol-ene "Click" Synthesis and Pharmacological Evaluation of C-Glycoside sp2-Iminosugar Glycolipids
(MDPI, 2019)The unique stereoelectronic properties of sp2-iminosugars enable their participation in glycosylation reactions, thereby ...
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Total asymmetric synthesis of monosaccharides and analogues
(Schweizerische Chemische Gesellschaft (Swiss Chemistry Society), 2011)Since the discovery of the 'formose reaction' by Butlerow,[1] total synthesis of carbohydrates has undergone rapid ...
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Toward a Suitable Structural Analysis of Gene Delivery Carrier Based on Polycationic Carbohydrates by Electron Transfer Dissociation Tandem Mass Spectrometry
(Elsevier, 2016)Polycationic carbohydrates represent an attractive class of biomolecules for several applications and particularly as non ...
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Toward fluorinated aminoglycosides: Structural studies of phenylhydrazine condensation with carbohydrate derivatives
(Georg Thieme Verlag, 2013)The reaction of phenylhydrazine with a sugar dialdehyde in water, as a key step for the synthesis of the 3-amino-3-deoxy-d-glucose ...
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Transferring Substituents from Alkynes to Furans and Pyrroles through Heteronorbornadienes as Intermediates: Synthesis of β-Substituted Pyrroles/Furans
(American Chemical Society, 2023)The use of 7-oxa/azanorbornadienes as synthetic intermediates for the preparation of 3/4-substituted (β-substituted) ...
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Trehalose-based Janus cyclooligosaccharides: the Click synthesis and DNA-directed assembly into pH-sensitive transfectious nanoparticles
(Royal Society of Chemistry, 2016)The convergent preparation of Janus molecular nanoparticles by thiourea-‘‘clicking’’ of a,a0 -trehalose halves has been ...
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Trehalose-based Siamese twin amphiphiles with tunable self-assembling, DNA nanocomplexing and gene delivery properties
(The Society, 2019-06-19)An original family of multivalent vectors encompassing gemini and facial amphiphilicity, namely cationic Siamese twin ...
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Trehalose-polyamine/DNA nanocomplexes: impact of vector architecture on cell and organ transfection selectivity
(Royal Society of Chemistry, 2024-03-05)A novel family of precision-engineered gene vectors with well-defined structures built on trehalose and trehalose-based ...
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Trifaceted Mickey Mouse Amphiphiles for Programmable Self-Assembly, DNA Complexation and Organ-Selective Gene Delivery
(Wiley, 2021)Instilling segregated cationic and lipophilic domains with an angular disposition in a trehalose-based trifaceted macrocyclic ...
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Trimethylsilylacetonitrile (TMSAN)
(2009)(A) The condensation of TMSAN with ketones in the presence of the catalytic t-Bu-P4 base to give cyanoalkenes has been ...
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Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors
(Taylor & Francis Open Access, 2021)We have designed unprecedented cholinesterase inhibitors based on 1-deoxynojirimycin as potential anti-Alzheimer’s agents. ...
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Uncovering a novel molecular mechanism for scavenging sialic acids in bacteria
(American Society for Biochemistry and Molecular Biology, 2020)The human gut symbiont Ruminococcus gnavus scavenges host-derived N-acetylneuraminic acid (Neu5Ac) from mucins by converting ...