Article
Studies on the Synthesis of 2-Alkyl-5-aryl-1,3,4-oxadiazolines from N-Acylhydrazones
Author/s | Marqués López, Eugenia
Díez Martín, Elena ![]() ![]() ![]() ![]() ![]() ![]() ![]() Martín Zamora, Eloísa Álvarez González, Eleuterio Fernández Fernández, Rosario Fátima ![]() ![]() ![]() ![]() ![]() ![]() ![]() Lassaletta Simón, José María |
Department | Universidad de Sevilla. Departamento de Química orgánica |
Date | 2012 |
Published in |
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Abstract | Reaction of N-acylhydrazones with benzyloxyacetyl chloride in the presence of i-Pr 2EtN affords new 1,3,4-oxadiazolines in excellent yields (72-95%), under mild reaction conditions and in short reaction times. The structures ... Reaction of N-acylhydrazones with benzyloxyacetyl chloride in the presence of i-Pr 2EtN affords new 1,3,4-oxadiazolines in excellent yields (72-95%), under mild reaction conditions and in short reaction times. The structures of the products were confirmed by single-crystal X-ray diffractometry. A plausible reaction mechanism is proposed |
Funding agencies | Ministerio de Ciencia e Innovación (MICIN). España Junta de Andalucía |
Citation | Marqués López, E., Díez Martín, E., Martín Zamora, E., Álvarez, E., Fernández Fernández, R. y Lassaletta Simón, J.M. (2012). Studies on the Synthesis of 2-Alkyl-5-aryl-1,3,4-oxadiazolines from N-Acylhydrazones. Synlett, 23 (6), 885-888. |
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