Listar Artículos (Química Orgánica) por título
Mostrando ítems 148-167 de 243
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P450BM3-Catalyzed Oxidations Employing Dual Functional Small Molecules
(MDPI, 2019)A set of dual functional small molecules (DFSMs) containing different amino acids has been synthesized and employed ...
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Pd-Catalyzed Dynamic Kinetic Asymmetric Cross-Coupling of Heterobiaryl Bromides with N-Tosylhydrazones
(American Chemical Society, 2022)A dynamic kinetic asymmetric Pd-catalyzed cross-coupling reaction of heterobiaryl bromides with ketone N-tosylhydrazones ...
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Pharmacological chaperone therapy for Gaucher disease: A patent review
(Taylor & Francis, 2011)Introduction: Mutations in the gene encoding for acid β-glucosidase (β-glucocerebrosidase, GlcCerase) are seen in Gaucher ...
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Pharmacological Chaperones and Coenzyme Q10 Treatment Improves Mutant β-Glucocerebrosidase Activity and Mitochondrial Function in Neuronopathic Forms of Gaucher Disease
(Nature Publishing Group, 2015)Gaucher disease (GD) is caused by mutations in the GBA1 gene, which encodes lysosomal β-glucocerebrosidase. Homozygosity ...
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Pharmacological Chaperones for the Treatment of α-Mannosidosis
(American Chemical Society, 2019)α-Mannosidosis (AM) results from deficient lysosomal α-mannosidase (LAMAN) activity and subsequent substrate accumulation ...
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Piperidine Azasugars Bearing Lipophilic Chains: Stereoselective Synthesis and Biological Activity as Inhibitors of Glucocerebrosidase (GCase)
(American Chemical Society, 2021)We report a straightforward synthetic strategy for the preparation of trihydroxypiperidine azasugars decorated with ...
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Plant Growth-Promoting Rhizobacteria Modulate the Concentration of Bioactive Compounds in Tomato Fruits
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)Background: The application of microorganisms as bioestimulants in order to increase the yield and/or quality of agricultural ...
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Polycyclic Ketone Monooxygenase (PockeMO): A Robust Biocatalyst for the Synthesis of Optically Active Sulfoxides
(Multidisciplinary Digital Publishing Institute (MDPI), 2017)recently discovered, moderately thermostable Baeyer-Villiger monooxygenase, polycyclic ketone monooxygenase (PockeMO), ...
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Positive impact of natural deep eutectic solvents on the biocatalytic performance of 5-hydroxymethyl-furfural oxidase
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)Deep eutectic solvents (DESs) have been applied as cosolvents in various biocatalytic processes during recent years. ...
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Preparation of Chitosan-supported Urea Materials and their Application in Some Organocatalytic Procedures
(Elsevier, 2018)An efficient and mild procedure was developed for the preparation of three chitosan-supported ureas containing ...
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Preparation of water-soluble glycopolymers derived from five-membered iminosugars
(Elsevier, 2019-10)Iminosugars are carbohydrate mimetics that constitute the main group of oligosaccharide processing enzyme inhibitors. ...
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Probing the Inhibitor versus Chaperone Properties of sp2-Iminosugars towards Human -Glucocerebrosidase: A Picomolar Chaperone for Gaucher Disease
(Molecular Diversity Preservation International, 2018)A series of sp2-iminosugar glycomimetics differing in the reducing or nonreducing character, the configurational pattern ...
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Probing the Inhibitor versus Chaperone Properties of sp2-Iminosugars towards Human β-Glucocerebrosidase: A Picomolar Chaperone for Gaucher Disease
(MDPI, 2021)A series of sp2-iminosugar glycomimetics differing in the reducing or nonreducing character, the configurational pattern ...
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(Pseudo)amide-linked oligosaccharide mimetics: molecular recognition and supramolecular properties
(Beilstein-Institut, 2010)Oligosaccharides are currently recognised as having functions that influence the entire spectrum of cell activities. ...
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Pyridine-Hydrazone Ligands in Asymmetric Palladium-Catalyzed 1,4- and 1,6-Additions of Arylboronic Acids to Cyclic (Di)enones
(Wiley-Blackwell, 2019)Catalysts generated by combinations of Pd(TFA)2 and enantiomerically pure pyridine-hydrazone ligands have been applied to ...
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Pyridine–hydrazone ligands in enantioselective palladium-catalyzed Suzuki–Miyaura cross-couplings
(Elsevier, 2016)The geometries and coordination properties of modular pyridineehydrazone N,N-ligands containing C2- symmetric ...
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Recent developments in the synthesis of β-diketones
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)Apart from being one of the most important intermediates in chemical synthesis, broadly used in the formation of C–C bonds ...
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Recent trends in synthetic enzymatic cascades promoted by alcohol dehydrogenases
(Elsevier, 2021)Alcohol dehydrogenases have fascinated chemists over the span of a few decades to catalyze oxidation and reduction reactions ...
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Reversible Light-Induced Dimerization of Secondary Face Azobenzene-Functionalized β-Cyclodextrin Derivatives
(American Chemical Society, 2023)β-cyclodextrin (βCyD) derivatives equipped with aromatic appendages at the secondary face exhibit tailorable self-assembling ...
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Rice and bean AHL-mimic quorum-sensing signals specifically interfere with the capacity to form biofilms by plant-associated bacteria
(2013)Many bacteria regulate their gene expression in response to changes in their population density in a process called quorum ...