idUS - Browsing Artículos (Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER)) by Title

Article

267 Spanish Exomes Reveal Population-Specific Differences in Disease-Related Genetic Variation

Dopazo, Joaquín; Amadoz, Alicia; Bleda, Marta; Garcia Alonso, Luz; Daub, Josephine T.; Antiñolo Gil, Guillermo; Bhattacharya, Shomi S. (Oxford University Press, 2016)

Recent results from large-scale genomic projects suggest that allele frequencies, which are highly relevant for medical ...

Article

A CDK-regulated chromatin segregase promoting chromosome replication

Chacin, Erika; Bansal, Priyanka; Reusswig, Karl-Uwe; Díaz Santín, Luis M.; Ortega Moreno, Pedro; Vizjak, Petra; Gómez González, Belén; Müller-Planitz, Felix; Aguilera López, Andrés; Pfander, Boris; Cheung, Alan C. M.; Kurat, Christoph F. (Springer Nature, 2021)

The replication of chromosomes during S phase is critical for cellular and organismal function. Replicative stress can ...

Article

A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs

García Muse, Tatiana; Galindo Díaz, U.; García Rubio, María Luisa; Martin, Julie S.; Polanowska, Jolanta; O'Reilly, N.; Aguilera López, Andrés; Boulton, Simon J. (Elsevier B.V., 2019)

Accurate meiotic chromosome segregation critically depends on the formation of inter-homolog crossovers initiated by ...

Article

A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice

Cañete, Ana; Carmona, Rita; Ariza, Laura; Sánchez, Mª José; Rojas, Anabel; Muñoz Chápuli, Ramón (Ferrata Storti Foundation, 2017)

GATA transcription factors are expressed in the mesoderm and endoderm during development. GATA1-3, but not GATA4, ...

Article

A positioned +1 nucleosome enhances promoter-proximal pausing

Jimeno González, Silvia; Ceballos Chávez, María; Reyes , José Carlos (Oxford University Press, 2015)

Chromatin distribution is not uniform along the human genome. In most genes there is a promoter-associated nucleosome free ...

Article

A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells

Dagg, Rebecca A.; Zonderland, Gijs; Puig Lombardi, Emilia; Rossetti, Giacomo G.; Groelly, Florian J.; Barroso Ceballos, Sonia Inés; Tacconi, Eliana M. C.; Wright, Benjamin; Lockstone, Helen; Aguilera López, Andrés; Halazonetis, Thanos D.; Tarsounas, Madalena (Springer Nature, 2021)

BRCA1 or BRCA2 germline mutations predispose to breast, ovarian and other cancers. High-throughput sequencing of tumour ...

Article

Actin nucleators safeguard replication forks by limiting nascent strand degradation

Nieminuszczy, J.; Martin, P. R.; Broderick, R.; Krwawicz, J.; Kanellou, A.; Mocanu, C.; Bousgouni, V.; Smith, C.; Aguilera López, Andrés; Niedzwiedz, Wojciech (Oxford University Press, 2023)

Accurate genome replication is essential for all life and a key mechanism of disease prevention, underpinned by the ability ...

Article

Adaptive response of saccharomyces hosts to totiviridae L-A dsRNA viruses Is achieved through intrinsically balanced action of targeted transcription factors

Ravoitytė, Bazilė; Lukša, Juliana; Wellinger, Ralf Erik; Serva, Saulius; Servienė, Elena (Multidisciplinary Digital Publishing Institute (MDPI), 2022)

Totiviridae L-A virus is a widespread yeast dsRNA virus. The persistence of the L-A virus alone appears to be symptomless, ...

Article

Adipose-derived mesenchymal stem cells (AdMSC) for the treatment of secondary-progressive multiple sclerosis: A triple blinded, placebo controlled, randomized phase I/II safety and feasibility study

Fernández, Oscar; Izquierdo Ayuso, Guillermo; Fernández Montesinos, Rafael; Pozo Pérez, David; Leyva, Laura (Public Library of Science, 2018)

Background Currently available treatments for secondary progressive multiple sclerosis(SPMS) have limited efficacy ...

Article

An improved system for estradiol-dependent regulation of gene expression in yeast

Chávez de Diego, Sebastián; Cebolla Ramírez, Ángel; Arévalo Rodríguez, Miguel; Quintero Carrasco, María José; Maya Miles, Douglas (2007)

Article

Analysis of the relationship between coexpression domains and chromatin 3D organization

Soler Oliva, María Eugenia; Guerrero Martínez, José A.; Bachetti, Valentina; Reyes, José C. (Public Library of Science, 2017)

Gene order is not random in eukaryotic chromosomes, and co-regulated genes tend to be clustered. The mechanisms that ...

Article

Application of flow focusing to the break-up of a magnetite suspension jet for the production of paramagnetic microparticles

Martín Banderas, Lucía; González Prieto, Román; Rodríguez Gil, Alfonso; Fernández Arévalo, María Mercedes; Flores Mosquera, María; Chávez de Diego, Sebastián; Gañán-Calvo, Alfonso M. (2011)

Paramagnetic particles offer an extensive improvement in the magnetic separation or purification of a wide variety of ...

Article

Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor

Peña, Álvaro; Gewartowski, Kamil; Mroczek, Seweryn; Cuéllar, Jorge; Szykowska, Aleksandra; Prokop, Andrzej; Czarnocki-Cieciura, Mariusz; Piwowarski, Jan; Tous Rivera, Cristina; Aguilera López, Andrés; Carrascosa, José L.; Valpuesta, José María; Dziembowski, Andrzej (Wiley-Blackwell, 2012)

The THO complex is a key factor in co-transcriptional formation of export-competent messenger ribonucleoprotein particles, ...

Article

ATRX-Deficient High-Grade Glioma Cells Exhibit Increased Sensitivity to RTK and PDGFR Inhibitors

Pladevall Morera, David; Castejón Griñán, María; Aguilera, Paula; Gaardahl, Karina; Ingham, Andreas; Brosnan Cashman, Jacqueline A.; Meeker, Alan K.; López Contreras, Andrés J. (MDPI, 2022)

High-grade glioma, including anaplastic astrocytoma and glioblastoma (GBM) patients, have a poor prognosis due to the lack ...

Article

Brahma is required for proper expression of the floral repressor FLC in Arabidopsis

Amasino, Richard M.; Farrona Cortés, Sara; Hurtado Álvarez, Lidia; Florencio Bellido, Francisco Javier; Reyes Rosa, José Carlos; March Díaz, Rosana Rocío; Schmitz, Robert J.; Turck, Franziska (2011)

Article

BRCA1 Accelerates CtIP-Mediated DNA-End Resection

Cruz García, Andrés; López Saavedra, Ana; Huertas Sánchez, Pablo (Elsevier, 2014)

DNA-end resection is a highly regulated and critical step in the response and repair of DNA double-strand breaks. In ...

Article

BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis

Salas Lloret, Daniel; García Rodríguez, Néstor; Soto Hidalgo, Emily; González Vinceiro, Lourdes; Espejo Serrano, Carmen; Giebel, Lisanne; Huertas Sánchez, Pablo; González Prieto, Román (Nature Research, 2024-05-20)

Deficiencies in the BRCA1 tumor suppressor gene are the main cause of hereditary breast and ovarian cancer. BRCA1 is ...

Article

Break-induced RNA–DNA hybrids (BIRDHs) in homologous recombination: friend or foe?

Gómez González, Belén; Aguilera López, Andrés (Wiley-Blackwell, 2023)

Double-strand breaks (DSBs) are the most harmful DNA lesions, with a strong impact on cell proliferation and genome ...

Article

CDK targets Sae2 to control DNA-end resection and homologous recombination

Huertas Sánchez, Pablo; Cortés Ledesma, Felipe; Sartori, Alessandro A.; Aguilera López, Andrés; Jackson, Stephen P. (Nature Publishing Group, 2008)

DNA double-strand breaks (DSBs) are repaired by two principal mechanisms: non-homologous end-joining (NHEJ) and homologous ...

Article

Cell consequences of loss of function of the epigenetic factor EHMT1

Iglesias Ortega, Lucía; Megías Fernández, Clara; Domínguez Giménez, Paloma; Jimeno González, Silvia; Rivero Canalejo, Sabrina (Elsevier, 2023)

EHMT1 is an epigenetic factor with histone methyltransferase activity that appears mutated in Kleefstra syndrome, a ...

Browsing Artículos (Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER)) by Title

267 Spanish Exomes Reveal Population-Specific Differences in Disease-Related Genetic Variation ﻿

A CDK-regulated chromatin segregase promoting chromosome replication ﻿

A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs ﻿

A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice ﻿

A positioned +1 nucleosome enhances promoter-proximal pausing ﻿

A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells ﻿

Actin nucleators safeguard replication forks by limiting nascent strand degradation ﻿

Adaptive response of saccharomyces hosts to totiviridae L-A dsRNA viruses Is achieved through intrinsically balanced action of targeted transcription factors ﻿

Adipose-derived mesenchymal stem cells (AdMSC) for the treatment of secondary-progressive multiple sclerosis: A triple blinded, placebo controlled, randomized phase I/II safety and feasibility study ﻿

An improved system for estradiol-dependent regulation of gene expression in yeast ﻿

Analysis of the relationship between coexpression domains and chromatin 3D organization ﻿

Application of flow focusing to the break-up of a magnetite suspension jet for the production of paramagnetic microparticles ﻿

Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor ﻿

ATRX-Deficient High-Grade Glioma Cells Exhibit Increased Sensitivity to RTK and PDGFR Inhibitors ﻿

Brahma is required for proper expression of the floral repressor FLC in Arabidopsis ﻿

BRCA1 Accelerates CtIP-Mediated DNA-End Resection ﻿

BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis ﻿

Break-induced RNA–DNA hybrids (BIRDHs) in homologous recombination: friend or foe? ﻿

CDK targets Sae2 to control DNA-end resection and homologous recombination ﻿

Cell consequences of loss of function of the epigenetic factor EHMT1 ﻿

267 Spanish Exomes Reveal Population-Specific Differences in Disease-Related Genetic Variation

A CDK-regulated chromatin segregase promoting chromosome replication

A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs

A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice

A positioned +1 nucleosome enhances promoter-proximal pausing

A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells

Actin nucleators safeguard replication forks by limiting nascent strand degradation

Adaptive response of saccharomyces hosts to totiviridae L-A dsRNA viruses Is achieved through intrinsically balanced action of targeted transcription factors

Adipose-derived mesenchymal stem cells (AdMSC) for the treatment of secondary-progressive multiple sclerosis: A triple blinded, placebo controlled, randomized phase I/II safety and feasibility study

An improved system for estradiol-dependent regulation of gene expression in yeast

Analysis of the relationship between coexpression domains and chromatin 3D organization

Application of flow focusing to the break-up of a magnetite suspension jet for the production of paramagnetic microparticles

Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor

ATRX-Deficient High-Grade Glioma Cells Exhibit Increased Sensitivity to RTK and PDGFR Inhibitors

Brahma is required for proper expression of the floral repressor FLC in Arabidopsis

BRCA1 Accelerates CtIP-Mediated DNA-End Resection

BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis

Break-induced RNA–DNA hybrids (BIRDHs) in homologous recombination: friend or foe?

CDK targets Sae2 to control DNA-end resection and homologous recombination

Cell consequences of loss of function of the epigenetic factor EHMT1