idUS - Browsing Artículos (Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER)) by Title

Article

267 Spanish Exomes Reveal Population-Specific Differences in Disease-Related Genetic Variation

Dopazo, Joaquín; Amadoz, Alicia; Bleda, Marta; Garcia Alonso, Luz; Daub, Josephine T.; Antiñolo Gil, Guillermo; Bhattacharya, Shomi S. (Oxford University Press, 2016)

Recent results from large-scale genomic projects suggest that allele frequencies, which are highly relevant for medical ...

Article

A CDK-regulated chromatin segregase promoting chromosome replication

Chacin, Erika; Bansal, Priyanka; Reusswig, Karl-Uwe; Díaz Santín, Luis M.; Ortega Moreno, Pedro; Vizjak, Petra; Gómez González, Belén; Müller-Planitz, Felix; Aguilera López, Andrés; Pfander, Boris; Cheung, Alan C. M.; Kurat, Christoph F. (Springer Nature, 2021)

The replication of chromosomes during S phase is critical for cellular and organismal function. Replicative stress can ...

Article

A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs

García Muse, Tatiana; Galindo Díaz, U.; García Rubio, María Luisa; Martin, Julie S.; Polanowska, Jolanta; O'Reilly, N.; Aguilera López, Andrés; Boulton, Simon J. (Elsevier B.V., 2019)

Accurate meiotic chromosome segregation critically depends on the formation of inter-homolog crossovers initiated by ...

Article

A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice

Cañete, Ana; Carmona, Rita; Ariza, Laura; Sánchez, Mª José; Rojas, Anabel; Muñoz Chápuli, Ramón (Ferrata Storti Foundation, 2017)

GATA transcription factors are expressed in the mesoderm and endoderm during development. GATA1-3, but not GATA4, ...

Article

A positioned +1 nucleosome enhances promoter-proximal pausing

Jimeno González, Silvia; Ceballos Chávez, María; Reyes , José Carlos (Oxford University Press, 2015)

Chromatin distribution is not uniform along the human genome. In most genes there is a promoter-associated nucleosome free ...

Article

A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells

Dagg, Rebecca A.; Zonderland, Gijs; Puig Lombardi, Emilia; Rossetti, Giacomo G.; Groelly, Florian J.; Barroso Ceballos, Sonia Inés; Tacconi, Eliana M. C.; Wright, Benjamin; Lockstone, Helen; Aguilera López, Andrés; Halazonetis, Thanos D.; Tarsounas, Madalena (Springer Nature, 2021)

BRCA1 or BRCA2 germline mutations predispose to breast, ovarian and other cancers. High-throughput sequencing of tumour ...

Article

Actin nucleators safeguard replication forks by limiting nascent strand degradation

Nieminuszczy, J.; Martin, P. R.; Broderick, R.; Krwawicz, J.; Kanellou, A.; Mocanu, C.; Bousgouni, V.; Smith, C.; Aguilera López, Andrés; Niedzwiedz, Wojciech (Oxford University Press, 2023)

Accurate genome replication is essential for all life and a key mechanism of disease prevention, underpinned by the ability ...

Article

Adaptive response of saccharomyces hosts to totiviridae L-A dsRNA viruses Is achieved through intrinsically balanced action of targeted transcription factors

Ravoitytė, Bazilė; Lukša, Juliana; Wellinger, Ralf Erik; Serva, Saulius; Servienė, Elena (Multidisciplinary Digital Publishing Institute (MDPI), 2022)

Totiviridae L-A virus is a widespread yeast dsRNA virus. The persistence of the L-A virus alone appears to be symptomless, ...

Article

Adipose-derived mesenchymal stem cells (AdMSC) for the treatment of secondary-progressive multiple sclerosis: A triple blinded, placebo controlled, randomized phase I/II safety and feasibility study

Fernández, Oscar; Izquierdo Ayuso, Guillermo; Fernández Montesinos, Rafael; Pozo Pérez, David; Leyva, Laura (Public Library of Science, 2018)

Background Currently available treatments for secondary progressive multiple sclerosis(SPMS) have limited efficacy ...

Article

An improved system for estradiol-dependent regulation of gene expression in yeast

Chávez de Diego, Sebastián; Cebolla Ramírez, Ángel; Arévalo Rodríguez, Miguel; Quintero Carrasco, María José; Maya Miles, Douglas (2007)

Article

Analysis of the relationship between coexpression domains and chromatin 3D organization

Soler Oliva, María Eugenia; Guerrero Martínez, José A.; Bachetti, Valentina; Reyes, José C. (Public Library of Science, 2017)

Gene order is not random in eukaryotic chromosomes, and co-regulated genes tend to be clustered. The mechanisms that ...

Article

Application of flow focusing to the break-up of a magnetite suspension jet for the production of paramagnetic microparticles

Martín Banderas, Lucía; González Prieto, Román; Rodríguez Gil, Alfonso; Fernández Arévalo, María Mercedes; Flores Mosquera, María; Chávez de Diego, Sebastián; Gañán-Calvo, Alfonso M. (2011)

Paramagnetic particles offer an extensive improvement in the magnetic separation or purification of a wide variety of ...

Article

Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor

Peña, Álvaro; Gewartowski, Kamil; Mroczek, Seweryn; Cuéllar, Jorge; Szykowska, Aleksandra; Prokop, Andrzej; Czarnocki-Cieciura, Mariusz; Piwowarski, Jan; Tous Rivera, Cristina; Aguilera López, Andrés; Carrascosa, José L.; Valpuesta, José María; Dziembowski, Andrzej (Wiley-Blackwell, 2012)

The THO complex is a key factor in co-transcriptional formation of export-competent messenger ribonucleoprotein particles, ...

Article

ATRX-Deficient High-Grade Glioma Cells Exhibit Increased Sensitivity to RTK and PDGFR Inhibitors

Pladevall Morera, David; Castejón Griñán, María; Aguilera, Paula; Gaardahl, Karina; Ingham, Andreas; Brosnan Cashman, Jacqueline A.; Meeker, Alan K.; López Contreras, Andrés J. (MDPI, 2022)

High-grade glioma, including anaplastic astrocytoma and glioblastoma (GBM) patients, have a poor prognosis due to the lack ...

Article

Brahma is required for proper expression of the floral repressor FLC in Arabidopsis

Amasino, Richard M.; Farrona Cortés, Sara; Hurtado Álvarez, Lidia; Florencio Bellido, Francisco Javier; Reyes Rosa, José Carlos; March Díaz, Rosana Rocío; Schmitz, Robert J.; Turck, Franziska (2011)

Article

BRCA1 Accelerates CtIP-Mediated DNA-End Resection

Cruz García, Andrés; López Saavedra, Ana; Huertas Sánchez, Pablo (Elsevier, 2014)

DNA-end resection is a highly regulated and critical step in the response and repair of DNA double-strand breaks. In ...

Article

Break-induced RNA–DNA hybrids (BIRDHs) in homologous recombination: friend or foe?

Gómez González, Belén; Aguilera López, Andrés (Wiley-Blackwell, 2023)

Double-strand breaks (DSBs) are the most harmful DNA lesions, with a strong impact on cell proliferation and genome ...

Article

CDK targets Sae2 to control DNA-end resection and homologous recombination

Huertas Sánchez, Pablo; Cortés Ledesma, Felipe; Sartori, Alessandro A.; Aguilera López, Andrés; Jackson, Stephen P. (Nature Publishing Group, 2008)

DNA double-strand breaks (DSBs) are repaired by two principal mechanisms: non-homologous end-joining (NHEJ) and homologous ...

Article

Cell consequences of loss of function of the epigenetic factor EHMT1

Iglesias Ortega, Lucía; Megías Fernández, Clara; Domínguez Giménez, Paloma; Jimeno González, Silvia; Rivero Canalejo, Sabrina (Elsevier, 2023)

EHMT1 is an epigenetic factor with histone methyltransferase activity that appears mutated in Kleefstra syndrome, a ...

Article

Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid

Burgos Morón, Estefanía; Calderón Montaño, José Manuel; Orta Vázquez, Manuel Luis; Guillén Mancina, Emilio; Mateos Cordero, Santiago; López Lázaro, Miguel (MDPI AG, 2016)

Epidemiological studies have found a positive association between coffee consumption and a lower risk of cardiovascular ...

Browsing Artículos (Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER)) by Title

267 Spanish Exomes Reveal Population-Specific Differences in Disease-Related Genetic Variation ﻿

A CDK-regulated chromatin segregase promoting chromosome replication ﻿

A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs ﻿

A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice ﻿

A positioned +1 nucleosome enhances promoter-proximal pausing ﻿

A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells ﻿

Actin nucleators safeguard replication forks by limiting nascent strand degradation ﻿

Adaptive response of saccharomyces hosts to totiviridae L-A dsRNA viruses Is achieved through intrinsically balanced action of targeted transcription factors ﻿

Adipose-derived mesenchymal stem cells (AdMSC) for the treatment of secondary-progressive multiple sclerosis: A triple blinded, placebo controlled, randomized phase I/II safety and feasibility study ﻿

An improved system for estradiol-dependent regulation of gene expression in yeast ﻿

Analysis of the relationship between coexpression domains and chromatin 3D organization ﻿

Application of flow focusing to the break-up of a magnetite suspension jet for the production of paramagnetic microparticles ﻿

Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor ﻿

ATRX-Deficient High-Grade Glioma Cells Exhibit Increased Sensitivity to RTK and PDGFR Inhibitors ﻿

Brahma is required for proper expression of the floral repressor FLC in Arabidopsis ﻿

BRCA1 Accelerates CtIP-Mediated DNA-End Resection ﻿

Break-induced RNA–DNA hybrids (BIRDHs) in homologous recombination: friend or foe? ﻿

CDK targets Sae2 to control DNA-end resection and homologous recombination ﻿

Cell consequences of loss of function of the epigenetic factor EHMT1 ﻿

Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid ﻿

267 Spanish Exomes Reveal Population-Specific Differences in Disease-Related Genetic Variation

A CDK-regulated chromatin segregase promoting chromosome replication

A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs

A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice

A positioned +1 nucleosome enhances promoter-proximal pausing

A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells

Actin nucleators safeguard replication forks by limiting nascent strand degradation

Adaptive response of saccharomyces hosts to totiviridae L-A dsRNA viruses Is achieved through intrinsically balanced action of targeted transcription factors

Adipose-derived mesenchymal stem cells (AdMSC) for the treatment of secondary-progressive multiple sclerosis: A triple blinded, placebo controlled, randomized phase I/II safety and feasibility study

An improved system for estradiol-dependent regulation of gene expression in yeast

Analysis of the relationship between coexpression domains and chromatin 3D organization

Application of flow focusing to the break-up of a magnetite suspension jet for the production of paramagnetic microparticles

Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor

ATRX-Deficient High-Grade Glioma Cells Exhibit Increased Sensitivity to RTK and PDGFR Inhibitors

Brahma is required for proper expression of the floral repressor FLC in Arabidopsis

BRCA1 Accelerates CtIP-Mediated DNA-End Resection

Break-induced RNA–DNA hybrids (BIRDHs) in homologous recombination: friend or foe?

CDK targets Sae2 to control DNA-end resection and homologous recombination

Cell consequences of loss of function of the epigenetic factor EHMT1

Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid