• Article
  

  SNRPD2 Is a Novel Substrate for the Ubiquitin Ligase Activity of the Salmonella Type III Secretion Effector SlrP 

  Bullones Bolaños, Andrea Simone; Araujo Garrido, Juan Luis; Fernández García, Jesús; Romero Portillo, Francisco; Bernal Bayard, Joaquín; Ramos Morales, Francisco (Multidisciplinary Digital Publishing Institute (MDPI), 2022)

  SlrP is a protein with E3 ubiquitin ligase activity that is translocated by Salmonella enterica serovar Typhimurium into ...

• Article
  

  Relation between CarS expression and activation of carotenogenesis by stress in Fusarium fujikuroi 

  Ruger Herreros, Macarena; Nordzieke, Steffen; Vega Álvarez, Carmen; Ávalos Cordero, Francisco Javier; Limón Mirón, María del Carmen (Frontiers Media S.A., 2022)

  Fusarium fujikuroi, a model organism for secondary metabolism in fungi, produces carotenoids, terpenoid pigments with ...

• Article
  

  FANCD2 maintains replication fork stability during misincorporation of the DNA demethylation products 5-hydroxymethyl-2’-deoxycytidine and 5-hydroxymethyl-2’-deoxyuridine 

  Peña Gómez, Mª José; Moreno Gordillo, Paula; Narmonté, Milda; García Calderón, Clara Beatriz; Ruksenaité, Audronė; Klimašauskas, Saulius; Valle Rosado, Iván (Springer Nature, 2022)

  Fanconi anemia (FA) is a rare hereditary disorder caused by mutations in any one of the FANC genes. FA cells are mainly ...

• Patent
  

  Empleo de una mutación en el gen de la deshidrogenasa de fitoeno de fusarium fujikuroi para produccion de gamma-caroteno y beta-caroteno. 

  Ávalos Cordero, Francisco Javier; Prado Cabrero, Alfonso (Oficina Española de Patentes y Marcas , 2005-05-01)

  Empleo de una mutación en el gen de la deshidrogenasa de fitoeno de fusarium fujikuroi para producción de gamma-caroteno ...

• Patent
  

  Procedimiento de expresion regulada de genes en celulas eucarioticas y elementos para su realizacion 

  Quintero Carrasco, Maria Jose; Arevalo Rodriguez, Miguel; Cebolla Ramirez, Angel; Chávez de Diego, Sebastián (Oficina Española de Patentes y Marcas , 2008-06-16)

  Procedimiento de expresión regulada de genes en células eucarióticas y elementos para su realización. La presente invención ...

• Patent
  

  Metodo para el ensayo de la expresion del genoma de una muestra biologica y kit para su realizacion. 

  Chávez de Diego, Sebastián; Rodriguez Gil, Alfonso (Oficina Española de Patentes y Marcas , 2008-10-16)

  Método para el ensayo de la expresión del genoma de una muestra biológica y kit para su realización.El objeto de la presente ...

• Article
  

  Adaptive response of saccharomyces hosts to totiviridae L-A dsRNA viruses Is achieved through intrinsically balanced action of targeted transcription factors 

  Ravoitytė, Bazilė; Lukša, Juliana; Wellinger, Ralf Erik; Serva, Saulius; Servienė, Elena (Multidisciplinary Digital Publishing Institute (MDPI), 2022)

  Totiviridae L-A virus is a widespread yeast dsRNA virus. The persistence of the L-A virus alone appears to be symptomless, ...

• Article
  

  Redox controls reca protein activity via reversible oxidation of its methionine residues 

  Henry, Camille; Loiseau, Laurent; Vergnes, Alexandra; Vertommen, Didier; Mérida Floriano, Ángela; Chitteni Pattu, Sindhu; Casadesús Pursals, Josep; Ezraty, Benjamin (eLife Sciences Publications, 2021)

  Reactive oxygen species (ROS) cause damage to DNA and proteins. Here we report that the RecA recombinase is itself oxidized ...

• Book
  

  Cuestión de sexo. Qué dice la biología acerca de la determinación sexual en humanos. Lección Inaugural del Aula de la Experiencia de la Universidad de Sevilla. Curso Académico 2017-2018 

  López Calderón, Isabel (Editorial Universidad de Sevilla, 2018)

  Lección inaugural del Aula de la Experiencia del curso 2017/2018 en el que la autora se decanta por tratar el tema de la ...

• Article
  

  Topoisomerase 1-dependent R-loop deficiency drives accelerated replication and genomic instability 

  Sarni, Dan; Barroso Ceballos, Sonia Inés; Shtrikman, Alon; Irony-Tur Sinai, Michal; Oren, Yifat S.; Aguilera López, Andrés; Kerem, Batsheva (Elsevier, 2022)

  DNA replication is a complex process tightly regulated to ensure faithful genome duplication, and its perturbation leads ...

• Article
  

  Genetic Mining of Newly Isolated Salmophages for Phage Therapy 

  Gendre, J.; Ansaldi, Mireille; Rodríguez Olivenza, David; Denis, Y.; Casadesús Pursals, Josep; Ginet, N. (Multidisciplinary Digital Publishing Institute (MDPI), 2022)

  Salmonella enterica, a Gram-negative zoonotic bacterium, is mainly a food-borne pathogen and the main cause of diarrhea ...

• Article
  

  CtIP-dependent nascent RNA expression flanking DNA breaks guides the choice of DNA repair pathway 

  Gómez Cabello, Daniel; Pappas, George; Aguilar Morante, Diana; Dinant, Christoffel; Bartek, Jiri (Springer Nature, 2022)

  The RNA world is changing our views about sensing and resolution of DNA damage. Here, we develop single-molecule DNA/RNA ...

• Article
  

  Nab2p and the Thp1p-Sac3p Complex Functionally Interact at the Interface between Transcription and mRNA Metabolism 

  Gallardo, Mercedes; Luna Varo, Rosa María; Erdjument-Bromage, Hediye; Tempst, Paul; Aguilera López, Andrés (Elsevier, 2003)

  THP1 is a conserved eukaryotic gene whose null mutations confer, in yeast, transcription and genetic instability phenotypes ...

• Article
  

  A role for the Saccharomyces cerevisiae Rtt109 histone acetyltransferase in R-loop homeostasis and associated genome instability 

  Cañas, Juan Carlos; García Rubio, María Luisa; García, Alicia; Antequera, Francisco; Gómez González, Belén; Aguilera López, Andrés (Genetics Society of America, 2022)

  The stability of the genome is occasionally challenged by the formation of DNA-RNA hybrids and R-loops, which can be ...

• Article
  

  The NEL Family of Bacterial E3 Ubiquitin Ligases 

  Bullones Bolaños, Andrea Simone; Bernal Bayard, Joaquín; Ramos Morales, Francisco (Multidisciplinary Digital Publishing Institute (MDPI), 2022)

  Some pathogenic or symbiotic Gram-negative bacteria can manipulate the ubiquitination system of the eukaryotic host cell ...

• Article
  

  Guidelines and recommendations on yeast cell death nomenclature 

  Carmona Gutiérrez, D.; Bauer, M. A.; Zimmermann, A.; Aguilera López, Andrés; Austriaco, N.; Ayscough, K.; Balzan, R.; Bar-Nun, S.; Madeo, F. (Shared Science Publishers, 2018)

  Elucidating the biology of yeast in its full complexity has major implications for science, medicine and industry. One of ...

• Article
  

  Survey of Early-Diverging Lineages of Fungi Reveals Abundant and Diverse Mycoviruses 

  Myers, J. M.; Bonds, A. E.; Clemons, R. A.; Thapa, N. A.; Simmons, D. R.; Carter-House, D.; Ortanez, J.; Liu, P.; Miralles Durán, Alejandro; Corrochano Peláez, Luis María; James, T. Y. (American Society for Microbiology, 2020)

  Mycoviruses are widespread and purportedly common throughout the fungal kingdom, although most are known from hosts in the ...

• Article
  

  Std fimbriae-fucose interaction increases Salmonella-induced intestinal inflammation and prolongs colonization 

  Suwandi, Abdulhadi; Galeev, Alibek; Riedel, René; Sharma, Samriti; Seeger, Katrin; Sterzenbach, Torsten; García Pastor, Lucía; Boyle, Erin C.; Casadesús Pursals, Josep; Grassl, Guntram A. (PLOS, 2019)

  Expression of ABO and Lewis histo-blood group antigens by the gastrointestinal epithelium is governed by an α-1,2-fucosyltransferase ...

• PhD Thesis
  

  Descripción y caracterización de la interacción física entre los complejos MCM y RNR en respuesta a daños en el ADN 

  Yáñez Vilches, Aurora (2022-05-24)

  El complejo MCM junto con el factor Cdc45 y el complejo GINS forman la helicasa replicativa en eucariotas, cuya actividad ...

• Article
  

  Ribosomal protein eL39 is important for maturation of the nascent polypeptide exit tunnel and proper protein folding during translation 

  Micic, Jelena; Rodríguez Galán, Olga; Babiano González, Reyes; Fitzgerald, Fiona; Fernández Fernández, José; Gao, Ning; Woolford, John L.; Cruz Díaz, Jesús de la (Oxford University Press, 2022)

  During translation, nascent polypeptide chains travel from the peptidyl transferase center through the nascent polypeptide ...

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