Genética
Collections in this community
Recent Submissions
-
PhD Thesis
Genome Instability Associated with DNA Topoisomerase Activity during Gene Transcription
(2023-07-07)Las lesiones que se producen en el ADN suponen un desafío continuo para la integridad genómica, siendo las roturas de ...
-
PhD Thesis
Activity of the CarS RING finger protein and regulatory connections with CwhA and HmbC in Fusarium fujikuroi
(2023-07-25)The genus Fusarium is a heterogeneous group of phytopathogenic fungi that causes diseases in a large diversity of economically ...
-
Article
N7-methylguanosine methylation of tRNAs regulates survival to stress in cancer
(Springer Nature, 2023)Tumour progression and therapy tolerance are highly regulated and complex processes largely dependent on the plasticity ...
-
Article
Recombineering 101: Making an in-Frame Deletion Mutant
(Cold Spring Harbor Laboratory Press, 2023)DNA recombineering uses phage λ Red recombination functions to promote integration of DNA fragments generated by polymerase ...
-
Article
HmbC, a Protein of the HMG Family, Participates in the Regulation of Carotenoid Biosynthesis in Fusarium fujikuroi
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)In the fungus Fusarium fujikuroi, carotenoid production is up-regulated by light and down-regulated by the CarS RING finger ...
-
Article
Nucleo-cytoplasmic Shuttling of RNA-binding Factors: mRNA Buffering and Beyond
(Elsevier, 2022)Gene expression is a highly regulated process that adapts RNAs and proteins content to the cellular context. Under ...
-
Article
Centriolar Subdistal Appendages Promote Double-strand Break Repair Through Homologous Recombination
(1469-3178, 2023)The centrosome is a cytoplasmic organelle with roles in microtu-bule organization that has also been proposed to act as a ...
-
Article
Escherichia coli SPFH Membrane Microdomain Proteins HflKC Contribute to Aminoglycoside and Oxidative Stress Tolerance
(American Society for Microbiology, 2023)Many eukaryotic membrane-dependent functions are often spatially and temporally regulated by membrane microdomains (FMMs), ...
-
Article
Actin nucleators safeguard replication forks by limiting nascent strand degradation
(Oxford University Press, 2023)Accurate genome replication is essential for all life and a key mechanism of disease prevention, underpinned by the ability ...
-
PhD Thesis
Unraveling the connection between centrosomes and the DNA damage response
(2023-06-20)Centrosomes act as the major microtubule (MT) organizing centers (MTOC) in most animal cells. Structural or numerical defects in this organelle are associated with ...
-
PhD Thesis
Molecular description of the role of protein synthesis in the cellular response to the treatment with the antitumoral drug Sorafenib in HCC lines
(2023-06-07)El carcinoma hepatocellular (CHC) es reconocido como el principal cáncer primario de hígado y uno de los cánceres con ...
-
PhD Thesis
Non-canonical DNA structures in Double Strand Break repair
(2023-05-22)DNA double-strand breaks (DSBs) pose a serious threat to genome stability, so their proper repair is crucial for cell ...
-
PhD Thesis
eL15 and eL22 proteins and their functional environments during ribosome assembly in Saccharomyces cerevisiae
(2023-05-18)Ribosomes are ribonucleoprotein complexes in charge of protein translation. Translation is an essential process in all ...
-
PhD Thesis
Molecular bases of proliferative heterogeneity in Saccharomyces cerevisiae
(2023-05-11)Proliferative heterogeneity has been widely described in clonal cultures, but the mechanisms underlying this phenomenon ...
-
Article
Fluorescent calixarene-schiff as a nanovehicle with biomedical purposes
(Multidisciplinary Digital Publishing Institute (MDPI), 2022-07-14)Gene therapy is a technique that is currently under expansion and development. Recent advances in genetic medicine have ...
-
Article
Cell consequences of loss of function of the epigenetic factor EHMT1
(Elsevier, 2023)EHMT1 is an epigenetic factor with histone methyltransferase activity that appears mutated in Kleefstra syndrome, a ...
-
Article
Special Issue: Type III Secretion Systems in Human/Animal Pathogenic Bacteria
(Multidisciplinary Digital Publishing Institute (MDPI), 2022) -
Article
Calmodulin in Paramecium: Focus on Genomic Data
(MDPI, 2022)Calcium (Ca2+) is a universal second messenger that plays a key role in cellular signaling. However, Ca2+ signals are ...
-
PhD Thesis
Insights into RNA-mediated genome instability by altering ALY expression and the use of new drugs
(2023-04-12)Las células han desarrollado una serie de mecanismos que utilizan de forma coordinada para mantener la integridad del ...
-
PhD Thesis
Transcriptional regulation by the Velvet complex during development in Neurospora crassa
(2023-04-21)Developmental transitions in fungi are key to their success in colonizing new habitats and adapting to stressful environmental ...