Genética
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Tesis Doctoral
Study of Pol5 protein from Saccharomyces cerevisiae and its human ortholog MYBBP1A in ribosome biogenesis
(2024-04-10)Los ribosomas son los orgánulos celulares que llevan a cabo el llamado proceso de traducción, en el cual las proteínas ...
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Expression of human RECQL5 in Saccharomyces cerevisiae causes transcription defects and transcription-associated genome instability
(Springer Nature, 2024-05-26)RECQL5 is a member of the conserved RecQ family of DNA helicases involved in the maintenance of genome stability that is ...
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Tesis Doctoral
Role of regulatory proteins in carotenoid biosynthesis and metabolism in Fusarium fujikuroi
(2024-04-12)La capacidad de los hongos filamentosos de adaptarse a cambios ambientales a cambios ambientales ha conducido al desarrollo ...
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BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis
(Nature Research, 2024-05-20)Deficiencies in the BRCA1 tumor suppressor gene are the main cause of hereditary breast and ovarian cancer. BRCA1 is ...
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Three Genes Involved in Different Signaling Pathways, carS, wcoA, and acyA, Participate in the Regulation of Fusarin Biosynthesis in Fusarium fujikuroi
(MDPI, 2024)The phytopathogenic fungus Fusarium fujikuroi has a rich secondary metabolism which includes the synthesis of very different ...
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SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability
(CELL PRESS (Elsevier), 2024)During genome duplication, replication forks (RFs) can be stalled by different obstacles or by depletion of replication ...
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Rat1 promotes premature transcription termination at R-loops
(Oxford University Press, 2024-04-24)Certain DNA sequences can adopt a non-B form in the genome that interfere with DNA-templated processes, including ...
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TDP1 suppresses chromosomal translocations and cell death induced by abortive TOP1 activity during gene transcription
(Nature Research, 2023-11-09)DNA topoisomerase I (TOP1) removes torsional stress by transiently cutting one DNA strand. Such cuts are rejoined by TOP1 ...
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Sperm-contributed centrioles segregate stochastically into blastomeres of 4-cell stage Caenorhabditis elegans embryos
(Oxford University Press, 2023-03-29)Whereas both sperm and egg contribute nuclear genetic material to the zygote in metazoan organisms, the inheritance of ...
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Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens
(Cell Press, 2023-08-03)To maintain genome integrity, cells must accurately duplicate their genome and repair DNA lesions when they occur. To ...
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Fusarium photoreceptors
(MDPI, 2023-03-04)Light is an important modulating signal in fungi. Fusarium species stand out as research models for their phytopathogenic ...
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Tesis Doctoral
Regulación y modificación de rutas biosintéticas de metabolitos con interés industrial en Fusarium fujikuroi
(2024-03-22)Los hongos filamentosos han sido utilizados como organismos modelos para el estudio de diferentes procesos biológicos ...
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Tesis Doctoral
Role of FACT and other chromatin-related factors in the origin of genetic instability
(2024-02-15)El mantenimiento de la integridad del genoma es un requisito indispensable para garantizar el correcto funcionamiento de ...
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Cannabinoids induce cell death in leukaemic cells through Parthanatos and PARP-related metabolic disruptions
(Nature Publishing Group, 2024)BACKGROUND: Several studies have described a potential anti-tumour effect of cannabinoids (CNB). CNB receptor 2 (CB2) is ...
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Transcription-driven DNA supercoiling counteracts H-NS-mediated gene silencing in bacterial chromatin.
(Nature Research, 2024-03-30)In all living cells, genomic DNA is compacted through interactions with dedicated proteins and/or the formation of plectonemic ...
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Analysis of Salmonella lineage-specific traits upon cell sorting
(Frontiers Media SA, 2023-03-29)Microbial cell individuality is receiving increasing interest in the scientific community. Individual cells within clonal ...
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Specificities and Redundancies in the NEL Family of Bacterial E3 Ubiquitin Ligases of Salmonella Enterica Serovar Typhimurium
(Frontiers Media, 2024)Salmonella enterica serovar Typhimurium expresses two type III secretion systems, T3SS1 and T3SS2, which are encoded in ...