Author profile: Rodríguez-Baño, Jesús
Institutional data
| Name | Rodríguez-Baño, Jesús |
| Department | Medicina |
| Knowledge area | Medicina |
| Professional category | Catedrático de Universidad (Pza. V.) |
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No. publications
158
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PhD Thesis
 Epidemiología de las bacteriemias en España y cambios epidemiológicos en las bacteriemias en Andalucía en la última década. Aplicación práctica en las bacteriemias no nosocomiales por P.aeruginosa: caracterización y desarrollo de score predictivo
(2024)
Las bacteriemias conforman un síndrome complejo y heterogéneo cuyo manejo clínico depende de múltiples factores, como las ... |
PhD Thesis
Farmacocinética y farmacodinamia de piperacilina/tazobactam y fosfomicina en pacientes con bacteriemia por enterobacteriaceae
(2024)
En esta tesis se aborda el estudio de la farmacocinética y farmacodinamia de dos antimicrobianos en bacteriemias por ... |
Article
Evaluation of temocillin efficacy against KPC-2-producing Klebsiella pneumoniae isolates in a hollow-fibre infection model
(Oxford University Press, 2024)
Background: Temocillin is an old antimicrobial that is resistant to hydrolysis by ESBLs but has variable activity against ... |
PhD Thesis
Factores de riesgo para el desarrollo de infecciones por enterobacterales productores de carbapenemasas
(2024)
INTRODUCCIÓN La resistencia a los antibióticos entre las bacterias ha sido reconocida como uno de los problemas de salud ... |
PhD Thesis
Bacteriemias relacionadas con catéter tunelizado en pacientes en hemodiálisis: factores de riesgo, pronóstico y manejo clínico
(2024)
Introducción. La bacteriemia relacionada con catéter tunelizado es una de las complicaciones más graves descritas entre ... |
Article
Antibiotic use and outcome in patients with negative blood cultures, a new target population for antimicrobial stewardship interventions: A prospective multicentre cohort (NO-BACT)
(Elsevier, 2024)
Objectives: To evaluate the appropriateness of antimicrobial treatment and the risk factors for mortality in patients with ... |
| Article |
PhD Thesis
Características, manejo clínico y pronóstico de las infecciones por Enterobacterales productores de carbapenemasas
(2023)
Antecedentes. La resistencia a los carbapenémicos (considerados como antibióticos de “último recurso”) hace cada vez más ... |
Article
Efficacy and safety of different antimicrobial DURATions for the treatment of Infections associated with Osteosynthesis Material implanted after long bone fractures (DURATIOM): Protocol for a randomized, pragmatic trial
(Public Library Science, 2023)
Background Infection associated with osteosynthesis material (IOM) is one of the most feared and challenging complications ... |
Article
Impact of adherence to individual quality-of-care indicators on the prognosis of bloodstream infection due to Staphylococcus aureus a prospective observational multicentre cohort
(Elsevier, 2023)
Objectives To analyse the adherence and impact of quality-of-care indicators (QCIs) in the management of Staphylococcus ... |
Article
Risk factors for infections caused by carbapenem-resistant Enterobacterales: an international matched case-control-control study (EURECA)
(2023)
Background Data on risk factors for carbapenem-resistant Enterobacterales (CRE) with wider applicability are needed to ... |
Article
Conventional hospitalization versus sequential outpatient parenteral antibiotic therapy for Staphylococcus aureus bacteremia: post-hoc analysis of a multicenter observational cohort
(MDPI, 2023)
It is not known whether sequential outpatient parenteral antimicrobial (OPAT) is as safe and effective as conventional ... |
Article
Effectiveness of fosfomycin trometamol as oral step-down therapy for bacteraemic urinary tract infections due to MDR Escherichia coli: a post hoc analysis of the FOREST randomized trial
(Oxford Academic, 2023)
Background Fosfomycin is a potentially attractive option as step-down therapy for bacteraemic urinary tract infections ... |
Article
Duration of antibiotic treatment for Gram-negative bacteremia – Systematic review and individual participant data (IPD) meta-analysis
(2023)
Background We aim to compare the effect of short versus long treatment duration in Gram-negative bacteremia on all-cause ... |
Article
 Circulating myeloid-derived suppressor cells may be a useful biomarker in the follow-up of unvaccinated COVID-19 patients after hospitalization
(Frontiers Media S.A., 2023)
SARS-CoV-2 infection is the cause of the disease named COVID-19, a major public health challenge worldwide. Differences ... |
| Article |
Article
Impact of COVID-19 pandemic on multidrug resistant gram positive and gram negative pathogens: a systematic review
(Elsevier, 2022)
Background: There is paucity of data describing the impact of COVID-19 pandemic on antimicrobial resistance. This review ... |
PhD Thesis
Oportunidades para la optimización del tratamiento antibiótico y pronóstico en pacientes con hemocultivo negativo (Proyecto NO-BACT)
(2022)
Los pacientes con sospecha de infección y extracción de hemocultivo son un grupo clínicamente heterogéneo. Dentro de ellos, ... |
Article
Treatments and Predictors of Mortality for Carbapenem-Resistant Gram-Negative Bacilli Infections in Malaysia A Retrospective Cohort Study
(MDPI, 2022)
This study evaluated the treatments, mortality rate and patient-related factors associated with mortality. This is a ... |
Article
EPI-Net One Health reporting guideline for antimicrobial consumption and resistance surveillance data: a Delphi approach
(Elsevier, 2022)
Strategic and standardised approaches to analysis and reporting of surveillance data are essential to inform antimicrobial ... |
Article
Rates and Predictors of Treatment Failure in Staphylococcus aureus Prosthetic Joint Infections According to Different Management Strategies A Multinational Cohort Study—The ARTHR-IS Study Group
(Springer, 2022)
Introduction Guidelines have improved the management of prosthetic joint infections (PJI). However, it is necessary to ... |
PhD Thesis
Programas de optimización de uso de antibióticos (PROA): evaluación de la calidad de uso de antimicrobianos e impacto de la auditoria en dos pasos desde la farmacia hospitalaria
(2022)
Introducción Los Programas de Optimización del uso de Antimicrobianos (PROA) tienen como objetivo principal mejorar los ... |
Article
Association of Patients’ Epidemiological Characteristics and Comorbidities with Severity and Related Mortality Risk of SARS-CoV-2 Infection Results of an Umbrella Systematic Review and Meta-Analysis
(MDPI, 2022)
The objective of this study was to assess the association between patients’ epidemiological characteristics and comorbidities ... |
Article
Tunneled catheter-related bacteremia in hemodialysis patients: incidence, risk factors and outcomes. A 14-year observational study
(SPRINGER, 2022)
Background Tunneled catheter-related bacteremia represents one of the major complications in patients on hemodialysis, and ... |
Article
"Pseudomonas aeruginosa" Community-Onset Bloodstream Infections: Characterization, Diagnostic Predictors, and Predictive Score Development-Results from the PRO-BAC Cohort
(MDPI, 2022)
Community-onset bloodstream infections (CO-BSI) caused by gram-negative bacilli are common and associated with significant ... |
Article
Association between Timing of Colonization and Risk of Developing Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae Infection in Hospitalized Patients
(AMER SOC MICROBIOLOGY, 2022)
Colonization by KPC-producing Klebsiella pneumoniae (KPC-Kp) is associ ated with the risk of developing KPC-Kp infection. ... |
Article
Effect of Glycerol on Fosfomycin Activity against Escherichia coli
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Fosfomycin is an antimicrobial that inhibits the biosynthesis of peptidoglycan by entering the bacteria through two channels ... |
Article
Duration of Treatment for Pseudomonas aeruginosa Bacteremia: a Retrospective Study
(SPRINGER LONDON LTD, 2022)
Introduction: There is no consensus regarding optimal duration of antibiotic therapy for Pseudomonas aeruginosa bacteremia. ... |
Article
Effectiveness of Fosfomycin for the Treatment of Multidrug-Resistant Escherichia coli Bacteremic Urinary Tract Infections A Randomized Clinical Trial
(Jama Nerwork Open, 2022)
Importance The consumption of broad-spectrum drugs has increased as a consequence of the spread of multidrug-resistant ... |
Article
Prevalence, Incidence, and Risk Factors for Intestinal Colonization Due to Fluoroquinolone-Resistant ST131 Escherichia coli: a Longitudinal Study in Highly Dependent, Long-Term Care Facility Residents
(American Society for Microbiology, 2022)
Escherichia coli ST131 clade C is an important driver for fluoroquinolone resistance (FQ-R). We conducted a prospective ... |
Article
Impact of antimicrobial stewardship programs on antibiotic consumption and antimicrobial resistance in four Colombian healthcare institutions
(Biomed Central LTD, 2022)
Background: Antimicrobial stewardship programs (ASPs) have become a fundamental pillar in optimizing antimicro‑ bial usage, ... |
Article
Association between rectal colonisation by Klebsiella pneumoniae carbapenemase-producing K. pneumoniae and mortality: a prospective, observational study
(Elsevier, 2022)
Objectives We evaluated the association of Klebsiella pneumoniae carbapenemase-producing K. pneumoniae (KPC-Kp) rectal ... |
Article
Assessing the Impact of SARS-CoV-2 Lineages and Mutations on Patient Survival
(MDPI, 2022)
Objectives: More than two years into the COVID-19 pandemic, SARS-CoV-2 still remains a global public health problem. ... |
Article
Impact of early interferon-β treatment on the prognosis of patients with COVID-19 in the first wave: A post hoc analysis from a multicenter cohort
(Elsevier France - Editions scientifiques medicales Elsevier, 2022)
Background: Interferon-β is an attractive drug for repurposing and use in the treatment of COVID-19, based on its in vitro ... |
Article
European Society of Clinical Microbiology and Infectious Diseases (ESCMID) guidelines for the treatment of infections caused by multidrug-resistant Gram-negative bacilli (endorsed by European society of intensive care medicine)
(Wiley-Blackwell, 2022)
Scope: These ESCMID guidelines address the targeted antibiotic treatment of third-generation cepha losporin-resistant ... |
Article
Evaluation of the kinetics of antibody response to COVID-19 vaccine in solid organ transplant recipients: the prospective multicenter orchestra cohort
(MDPI, 2022)
Previous studies assessing the antibody response (AbR) to mRNA COVID-19 vaccines in solid organ transplant (SOT) recipients ... |
Article
Off-target effects of bacillus Calmette–Guerin vaccination on immune responses to SARS-CoV-2: implications for protection against severe COVID-19
(WILEY, 2022)
Background and objectives. Because of its beneficial off-target effects against non-mycobacterial infectious diseases, ... |
Article
Populations of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae are different in human-polluted environment and food items: a multicentre European study
(Elsevier, 2022)
Objectives To assess the extent to which food items are a source of extended-spectrum β-lactamase (ESBL) -producing ... |
Article
Persistence of SARS-CoV-2 Infection in Severely Immunocompromised Patients With Complete Remission B-Cell Lymphoma and Anti-CD20 Monoclonal Antibody Therapy: A Case Report of Two Cases
(Frontiers Media S.A., 2022)
Immunosuppressant conditions such as hematological malignancies increase the risk of severe acute respiratory syndrome ... |
Article
Predictors of inappropriate antimicrobial prescription: Eight-year point prevalence surveys experience in a third level hospital in Spain
(Frontiers Media S.A., 2022)
Antibiotic stewardship programs (ASP) have already demonstrated clinical benefits. We aimed to describe the Point Prevalence ... |
Article
Extended-spectrum beta-lactamase-producing and carbapenem-resistant enterobacterales bloodstream infection after solid organ transplantation: recent trends in epidemiology and therapeutic approaches
(Wiley-Blackwell, 2022)
Background: Infections caused by multidrug-resistant gram-negative bacilli (MDR GNB), in particular extended-spectrum ... |
Article
Healthcare-associated infections in Africa: a systematic review and meta-analysis of point prevalence studies
(2022)
Background: There is limited data to describe the point-prevalence of healthcare-associated infections (HAIs) among patients ... |
Article
Pseudomonas aeruginosa Community-Onset Bloodstream Infections: Characterization, Diagnostic Predictors, and Predictive Score Development—Results from the PRO-BAC Cohort
(MDPI, 2022)
Community-onset bloodstream infections (CO-BSI) caused by gram-negative bacilli are common and associated with significant ... |
Article
What is the evidence base of used aggregated antibiotic resistance percentages to change empirical antibiotic treatment? A scoping review
(Elsevier, 2021)
Objectives Antibiotic resistance requires continuous monitoring by experts to decide whether empirical antibiotic therapies ... |
Article
Real world evidence of calcifediol or vitamin D prescription and mortality rate of COVID-19 in a retrospective cohort of hospitalized Andalusian patients
(Nature Research, 2021)
COVID-19 is a major worldwide health problem because of acute respiratory distress syndrome, and mortality. Several lines ... |
Article
Interplay between IncF plasmids and topoisomerase mutations conferring quinolone resistance in the Escherichia coli ST131 clone: stability and resistance evolution
(Springer, 2021)
The Escherichia coli ST131 H30-Rx subclone vehicles CTX-M-15 plasmids and mutations in gyrA and parC conferring multidrug ... |
Article
Implementing personalized medicine in covid-19 in andalusia: an opportunity to transform the healthcare system
(MDPI, 2021)
The COVID-19 pandemic represents an unprecedented opportunity to exploit the advantages of personalized medicine for the ... |
Article
Early Stepdown From Echinocandin to Fluconazole Treatment in Candidemia: A Post Hoc Analysis of Three Cohort Studies
(Oxford University Press, 2021)
Background There are no clear criteria for antifungal de-escalation after initial empirical treatments. We hypothesized ... |
Article
Population pharmacokinetics of piperacillin in non-critically ill patients with bacteremia caused by enterobacteriaceae
(MDPI, 2021)
This study analyzes the pharmacokinetic variability of piperacillin in non-critically ill patients with Enterobacteriaceae ... |
Article
CON: carbapenems are NOT necessary for all infections caused by ceftriaxone-resistant enterobacterales
(2021)
Carbapenems are considered the drugs of choice for the treatment of serious infections caused by ceftriaxone resistant ... |
Article
Key considerations on the potential impacts of the COVID-19 pandemic on antimicrobial resistance research and surveillance
(OXFORD UNIV PRESS, 2021)
Antibiotic use in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients during the COVID-19 pandemic has ... |
Article
Efficacy of β-lactam/β-lactamase inhibitors to treat extended-spectrum beta-lactamase-producing Enterobacterales bacteremia secondary to urinary tract infection in kidney transplant recipients
(Willey-Blackwell, 2021)
Background Whether active therapy with β-lactam/β-lactamase inhibitors (BLBLI) is as affective as carbapenems for ... |
Article
Incidence and predictive biomarkers of Clostridioides difficile infection in hospitalized patients receiving broad-spectrum antibiotics
(Nature Publishing Group, 2021)
Trial enrichment using gut microbiota derived biomarkers by high-risk individuals can improve the feasibility of randomized ... |
Article
Interplay Among Different Fosfomycin Resistance Mechanisms in Klebsiella Pneumoniae
(American Society for Microbiology, 2021)
The objectives of this study were to characterize the role of the uhpT, glpT, and fosA genes in fosfomycin resistance in ... |
Article
Phenotypic and molecular characterizations of carbapenem-resistant Acinetobacter baumannii isolates collected within the EURECA study
(Elsevier Science, 2021)
Multi-drug-resistant Acinetobacter baumannii isolates are key pathogens that contribute to the global bur den of antimicrobial ... |
Article
Development and validation of a prediction model for 30-day mortality in hospitalised patients with COVID-19: the COVID-19 SEIMC score
(BMJ PUBLISHING GROUP, 2021)
Objective: To develop and validate a prediction model of mortality in patients with COVID-19 attending hospital emergency ... |
Article
Evaluation of a loop-mediated isothermal amplification assay to detect carbapenemases directly from bronchoalveolar lavage fluid spiked with acinetobacter spp
(Methods, 2021)
Carbapenem-resistant Acinetobacter spp. mainly Acinetobacter baumannii are frequently causing nosocomial infections with ... |
Article
Efficacy of Fosfomycin and Its Combination With Aminoglycosides in an Experimental Sepsis Model by Carbapenemase-Producing Klebsiella pneumoniae Clinical Strains
(Frontiers Media, 2021)
Carbapenemase-producing Klebsiella pneumoniae infections are an increasing global threat with scarce and uncertain treatment ... |
Article
Antimicrobial resistance research in a post-pandemic world: insights on antimicrobial resistance research in the COVID-19 pandemic
(Elsevier, 2021)
Antimicrobial resistance must be recognised as a global societal priority - even in the face of the worldwide challenge ... |
Article
Propensity score and desirability of outcome ranking analysis of ertapenem for treatment of nonsevere bacteremic urinary tract infections due to extended-spectrum-beta-lactamase-producing enterobacterales in kidney transplant recipients
(American Society Microbiology, 2021)
There are scarce data on the efficacy of ertapenem in the treatment of bacteremia due to extended-spectrum-beta-lactamase ... |
Article
Microbiota-based markers predictive of development of Clostridioides difficile infection
(Nature Publishing Group, 2021)
Antibiotic-induced modulation of the intestinal microbiota can lead to Clostridioides difficile infection (CDI), which is ... |
Article
Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)
(Science Direct, 2021)
Objectives The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk ... |
Article
An International Prospective Cohort Study To Validate 2 Prediction Rules for Infections Caused by Third-generation Cephalosporin-resistant Enterobacterales
(Oxford University Press, 2021)
Background The possibility of bloodstream infections caused by third-generation cephalosporin-resistant Enterobacterales ... |
Article
Risk factors for carbapenem-resistant Gram-negative bacterial infections: a systematic review
(Science Direct, 2021)
ackground Rapid and widespread increases in carbapenem resistance (CR) necessitate identification of risk factors to guide ... |
Article
Clinical characteristics and outcome of bacteraemia caused by Enterobacter cloacae and Klebsiella aerogenes: more similarities than differences
(Elsevier, 2021)
Objectives The genus Enterobacter is a common cause of nosocomial infections. Historically, the most frequent Enterobacter ... |
Article
Identification and validation of clinical phenotypes with prognostic implications in patients admitted to hospital with COVID-19: a multicentre cohort study
(Elsevier, 2021)
Background The clinical presentation of COVID-19 in patients admitted to hospital is heterogeneous. We aimed to determine ... |
Article
Temocillin versus meropenem for the targeted treatment of bacteraemia due to third-generation cephalosporin-resistant Enterobacterales (ASTARTÉ): protocol for a randomised, pragmatic trial
(BMJ Publishing Group, 2021)
Introduction: Alternatives to carbapenems are needed in the treatment of third-generation cephalosporin-resistant ... |
Article
Liver manifestations in COVID-19 and the influence of pre-existing liver disease in the course of the infection
(Arán Ediciones, S.L., 2021)
Introduction: patients with advanced chronic liver disease (CLD) may be at an increased risk of a severe course due ... |
Article
Household acquisition and transmission of extended-spectrum β-lactamase (ESBL) -producing Enterobacteriaceae after hospital discharge of ESBL-positive index patients
(Elsevier, 2021)
Objectives: This study aimed to determine rates and risk factors of extended-spectrum b-lactamaseproducing Enterobacteriaceae ... |
PhD Thesis
Caracterización epidemiológica y clínica de la infección y colonización por Escherichia coli perteneciente al complejo clonal O25b/ST131
(2020)
Introducción. Escherichia coli secuenciotipo 131 (ST131) es un clon que combina capacidad de propagación exitosa, resistencia ... |
Article
Predictors of mortality in solid organ transplant recipients with bloodstream infections due to carbapenemase-producing Enterobacterales: the impact of cytomegalovirus disease and lymphopenia
(BMC, 2020)
Treatment of carbapenemase-producing Enterobacterales bloodstream infections in solid organ transplant recipients is ... |
Article
Risk perception of antimicrobial resistance by infection control specialists in Europe: a case-vignette study
(Nature Publishing Group, 2020)
Background Using case-vignettes, we assessed the perception of European infection control (IC) specialists regarding the ... |
Article
A one health framework to estimate the cost of antimicrobial resistance
(BMC, 2020)
Objectives/purpose: The costs attributable to antimicrobial resistance (AMR) remain theoretical and largely unspecified. Current ... |
Article
A framework to develop semiautomated surveillance of surgical site infections: An international multicenter study
(Cambridge University Press, 2020)
Objective: Automated surveillance of healthcare-associated infections reduces workload and improves standardization, but ... |
Article
Optimizing design of research to evaluate antibiotic stewardship interventions: consensus recommendations of a multinational working group
(Elsevier, 2020)
Background Antimicrobial stewardship interventions and programmes aim to ensure effective treatment while minimizing ... |
Article
Systematic literature review of the burden and outcomes of infections due to multidrug-resistant organisms in Europe: the ABOUT-MDRO project protocol
(BMJ Publishing Group, 2020)
Introduction: Despite the increasing importance of infections due to multidrug-resistant organisms (MDROs), there is a ... |
Article
Global Evolution of Pathogenic Bacteria With Extensive Use of Fluoroquinolone Agents
(Frontiers Media, 2020)
It is well-established that the spread of many multidrug-resistant (MDR) bacteria is predominantly clonal. Interestingly ... |
Article
Mandatory surveillance and outbreaks reporting of the WHO priority pathogens for research & discovery of new antibiotics in European countries
(Elsevier, 2020)
Objectives: In 2017 the WHO published a global priority list of 12 antibiotic-resistant bacteria (ARB) in urgent need of ... |
Article
Contribution of hypermutation to fosfomycin heteroresistance in Escherichia coli
(Oxford University Press, 2020)
Objectives: To explore the effect of combining defects in DNA repair systems with the presence of fosfomycin-resistant ... |
PhD Thesis
Seguimiento del estado de portador de enterobacterias productoras de beta-lactamasas de espectro extendido en recién nacidos sanos: estudio NEOBLEE.
(2019)
Introducción Las beta-lactamasas de espectro extendido (BLEE) confieren resistencia a las penicilinas y cefalosporinas, ... |
Article
The impact of initial antibiotic treatment failure: Real-world insights in patients with complicated, health care-associated intra-abdominal infection
(Dove, 2019)
Purpose: The RECOMMEND study (NCT02364284; D4280R00005) assessed the clinical management patterns and treatment outcomes ... |
Article
Combined use of the Ab105-2фΔCI lytic mutant phage and different antibiotics in clinical isolates of multiresistant Acinetobacter baumannii
(2019)
Phage therapy is an abandoned antimicrobial therapy that has been resumed in recent years. In this study, we mutated ... |
Article
Does Online Search Behavior Coincide with Candida auris Cases? An Exploratory Study
(MDPI, 2019)
Candida auris is an emerging multidrug resistant infectious yeast which is challenging to eradicate and despite available ... |
Article
Impact of De-escalation on Prognosis of Patients With Bacteremia due to Enterobacteriaceae: A Post Hoc Analysis From a Multicenter Prospective Cohort
(Oxford University Press, 2019)
Background More data are needed about the safety of antibiotic de-escalation in specific clinical situations as a strategy ... |
Article
Opportunities for antibiotic optimisation and outcome improvement in patients with negative blood cultures: study protocol for a cluster-randomised crossover trial, the NO-BACT study.
(2018)
Introduction Patients with negative blood cultures (BCx) represent 85%–90% of all patients with BCx taken during hospital ... |
Article
Relationship Between the Quorum Network (Sensing/Quenching) and Clinical Features of Pneumonia and Bacteraemia Caused by A. baumannii
(Frontiers Research Foundation, 2018)
Acinetobacter baumannii (Ab) is one of the most important pathogens associated with nosocomial infections, especially ... |
Article
Intestinal colonization due to Escherichia coli ST131: Risk factors and prevalence
(Biomed Central, 2018)
Background Escherichia coli sequence type 131 (ST131) is a successful clonal group that has dramatically spread during the ... |
Article
Social media posts and online search behaviour as early-warning system for MRSA outbreaks
(2018)
Background: Despite many preventive measures, outbreaks with multi-drug resistant micro-organisms (MDROs) still occur. ... |
Article
 Duration of Colonization by Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae in Healthy Newborns and Associated Risk Factors: a Prospective Cohort Study
(Oxford University Press, 2018)
Duration of colonization by extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) and factors associated ... |
Article
Prevalence and transmission dynamics of Escherichia coli ST131 among contacts of infected community and hospitalized patients
(Elsevier, 2018)
Objectives: The Escherichia coli O25b-associated ST131 clonal group was recently found to be prevalent in our area as a ... |
Article
Análisis de la calidad de uso de antimicrobianos en el servicio de urgencias de un hospital de tercer nivel
(Sanidad Ediciones, 2018)
Objetivo. Describir los factores modificables relacionados con el tratamiento antimicrobiano (TA) inadecuado en el área ... |
Article
Population pharmacokinetics and pharmacodynamics of fosfomycin in non-critically ill patients with bacteremic urinary infection caused by multidrug-resistant Escherichia coli
(Elsevier, 2018)
Objectives: To describe the population pharmacokinetics of fosfomycin for patients with bacteraemic urinary tract infection ... |
| PhD Thesis |
PhD Thesis
Impacto de la concentración mínima inhibitoria (cmi) y de los puntos de corte clínicos (clsi y eucast) de las combinaciones betalactámicos / inhibidores de betalactamasas en el pronóstico de bacteriemias por enterobacteriaceae
(2017)
Los puntos de corte clínicos se utilizan para predecir la eficacia terapéutica de un antibiótico cuando se utiliza a la ... |
| PhD Thesis |
| PhD Thesis |
Article
Targeted Simplification Versus Antipseudomonal Broad-Spectrum Beta-Lactams in Patients With Bloodstream Infections Due to Enterobacteriaceae (SIMPLIFY): A Study Protocol for a Multicentre, Open-Label, Phase III Randomised, Controlled, Non-Inferiority Clinical Trial.
(2017)
Introduction Within the context of antimicrobial stewardship programmes, de-escalation of antimicrobial therapy is one of ... |
Article
EUropean prospective cohort study on Enterobacteriaceae showing REsistance to CArbapenems (EURECA): a protocol of a European multicentre observational study
(2017)
Introduction: The rapid worldwide spread of carbapenem-resistant Enterobacteriaceae (CRE) constitutes a major challenge. ... |
Article
Clinical efficacy of β-lactam/β-lactamase inhibitor combinations for the treatment of bloodstream infection due to extended-spectrum β-lactamase- producing Enterobacteriaceae in haematological patients with neutropaenia: a study protocol for a retrospect observational study (BICAR)
(2017)
Introduction: Bloodstream infection (BSI) due to extended-spectrum β-lactamase-producing Gram- negative bacilli (ESBL-GNB) ... |
Article
Bacteraemia due to non-ESBL-producing Escherichia coli O25b:H4 sequence type 131: insights into risk factors, clinical features and outcomes
(Elsevier, 2017)
The epidemiology and outcomes of bloodstream infections (BSIs) caused by Escherichia coli ST131 isolates not producing ... |
Article
The Global Alliance for Infections in Surgery: defining a model for antimicrobial stewardship—results from an international cross-sectional survey
(BMC, 2017)
Background: Antimicrobial Stewardship Programs (ASPs) have been promoted to optimize antimicrobial usage and patient ... |
Article
Surveillance Systems from Public Health Institutions and Scientific Societies for Antimicrobial Resistance and Healthcare-Associated Infections in Europe (SUSPIRE): protocol for a systematic review
(BMJ Publishing Group, 2017)
Introduction The worldwide spread of antimicrobial resistance is now recognised as a global public health threat. Owing ... |
Article
A multinational, preregistered cohort study of β-lactam/β-lactamase inhibitor combinations for treatment of bloodstream infections due to extended-spectrum-β-lactamase-producing enterobacteriaceae
(American Society for Microbiology, 2016)
The spread of extended-spectrum-β-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-E) is leading to increased carbapenem ... |
Article
Modelling the epidemiology of Escherichia coli ST131 and the impact of interventions on the community and healthcare centres
(Cambridge University Press, 2016)
ST131 Escherichia coli is an emergent clonal group that has achieved successful worldwide spread through a combination of ... |
Article
Genomic Evolution of Two Acinetobacter baumannii Clinical Strains from ST-2 Clones Isolated in 2000 and 2010 (ST-2_clon_2000 and ST-2_clon_2010)
(2016)
Acinetobacter baumannii is a successful nosocomial pathogen due to its ability to persist in hospital environments by ... |
PhD Thesis
Niveles de ansiedad y depresión en los fumadores que acuden a una consulta de deshabituación tabáquica y factores relacionados
(2015)
Se sabe que los fumadores tienen más riesgo de desarrollar un trastorno mental que aquellos que no fuman, presentando según ... |
Article
Pharmacodynamics of fosfomycin: Insights into clinical use for antimicrobial resistance
(American Society for Microbiology, 2015)
The aim of this study was to improve the understanding of the pharmacokinetic-pharmacodynamic relationships of fosfomycin ... |
PhD Thesis
Tratamiento de bacteriemias por enterobacterias productoras de β-lactamasas de espectro extendido la combinación de β-lactámicosinhibidores de β-lactamasas como alternativa a los carbapenemes. Proyecto INCREMENT
(2015)
En los últimos años, la diseminación de las enterobacterias productoras de β-lactamasas de espectro extendido (E-BLEE) se ... |
PhD Thesis
Estudio clínico y epidemiológico de un brote nosocomial producido por klebsiella oxytoca productora de IMP-8
(2015)
Klebsiella oxytoca, al igual que K. pneumoniae, son dos patógenos humanos asociados a múltiples cuadros clínicos, pero ... |
Article
Fosfomycin versus meropenem in bacteraemic urinary tract infections caused by extended-spectrum β-lactamase-producing Escherichia coli (FOREST): study protocol for an investigator-driven randomised controlled trial
(BMJ Publishing Group, 2015)
Introduction Finding therapeutic alternatives to carbapenems in infections caused by extended-spectrum β-lactamase-producing ... |
Article
Is reduced vancomycin susceptibility a factor associated with poor prognosis in MSSA bacteraemia?
(Oxford University Press, 2015)
Objectives: The known data about the influence of vancomycin MIC on Staphylococcus aureus bacteraemia are contradictory. ... |
Article
The global threat of antimicrobial resistance: science for intervention
(2015)
In the last decade we have witnessed a dramatic increase in the proportion and absolute number of bacterial pathogens ... |
PhD Thesis
Caracterización de aislados de Escherichia coli de origen clínico y alimentario productores de batalactamasas de espectro extendido
(2014)
Escherichia coli, perteneciente a la familia Enterobacteriaceae, es el comensal más prevalente en el tracto gastrointestinal ... |
PhD Thesis
Estudio multicéntrico de bacteriemias por escherichia coli productor de betalactamasas de espectro extendido: factores de riesgo, características microbiológicas de impacto clínico
(2014)
Esta tesis es el resultado de un estudio de investigación multicéntrico en el que participaron 13 hospitales y un centro ... |
Article
Global dissemination of a multidrug resistant Escherichia coli clone
(National Academy of Sciences, 2014)
Escherichia coli sequence type 131 (ST131) is a globally disseminated, multidrug resistant (MDR) clone responsible for a ... |
Article
Predictors of early mortality in very elderly patients with bacteremia: a prospective multicenter cohort
(Elsevier, 2014)
Objectives: The proportion of very elderly people in the population is increasing, and infectious diseases in this patient ... |
Article
Epidemiologic and Clinical Impact of Acinetobacter baumannii Colonization and Infection: A Reappraisal
(Lippincott Williams & Wilkins, 2014)
Acinetobacter baumannii is one of the most important antibiotic-resistant nosocomial bacteria. We investigated changes in ... |
Article
Staphylococcus aureus bloodstream infection: A pooled analysis of five prospective, observational studies
(W.B. Saunders Co. Ltd., 2014)
Objectives: Staphylococcus aureus bacteraemia is a common, often fatal infection. Our aim was to describe how its clinical ... |
Article
Contribution of Efflux Pumps, Porins, and B-Lactamases to Multidrug Resistance in Clinical Isolates of Acinetobacter baumannii
(American Society for Microbiology, 2013)
Weinvestigated the mechanisms of resistance to carbapenems, aminoglycosides, glycylcyclines, tetracyclines, and quinolones ... |
Article
Four main virotypes among extended-spectrum-β-lactamase-producing isolates of Escherichia coli O25b:H4-B2-ST131: bacterial, epidemiological, and clinical characteristics
(American Society for Microbiology, 2013)
A total of 1,021 extended-spectrum- -lactamase-producing Escherichia coli (ESBLEC) isolates obtained in 2006 during a ... |
Article
Impact of the MIC of Piperacillin-Tazobactam on the Outcome of Patients with Bacteremia Due to Extended-Spectrum-B-Lactamase- Producing Escherichia coli
(American Society for Microbiology, 2013)
We investigated the impact of the piperacillin-tazobactam MIC in the outcome of 39 bloodstream infections due to ... |
Article
Epidemiological and Clinical Complexity of Amoxicillin-Clavulanate- Resistant Escherichia coli
(American Society for Microbiology, 2013)
Two hundred twelve patients with colonization/infection due to amoxicillin-clavulanate (AMC)-resistant Escherichia coli ... |
Article
Inoculum Effect on the Efficacies of Amoxicillin-Clavulanate, Piperacillin-Tazobactam, and Imipenem against Extended-Spectrum -Lactamase (ESBL)-Producing and Non-ESBL-Producing Escherichia coli in an Experimental Murine Sepsis Model
(American Society for Microbiology, 2013)
Escherichia coli is commonly involved in infections with a heavy bacterial burden. Piperacillin-tazobactam and carbapenems ... |
Article
Prevalence of and Risk Factors for Biliary Carriage of Bacteria Showing Worrisome and Unexpected Resistance Traits
(American Society for Microbiology, 2013)
Data on biliary carriage of bacteria and, specifically, of bacteria with worrisome and unexpected resistance traits (URB) ... |
Article
First Report of an OXA-23 Carbapenemase-Producing Acinetobacter baumannii Clinical Isolate Related to Tn2006 in Spain
(American Society for Microbiology, 2013)
A carbapenem-resistant Acinetobacter baumannii clinical isolate belonging to European clone II and sequence type 2 was ... |
Article
Effect of Statin Therapy in the Outcome of Bloodstream Infections Due to Staphylococcus aureus: A Prospective Cohort Study
(Public Library of Science (PLoS), 2013)
Introduction: Statins have pleiotropic effects that could influence the prevention and outcome of some infectious ... |
Article
Reappraisal of the outcome of healthcare-associated and community-acquired bacteramia: a prospective cohort study
(BioMed Central, 2013)
Background: Healthcare-associated (HCA) bloodstream infections (BSI) have been associated with worse outcomes, in terms ... |
Article
‘‘The 3/3 Strategy’’: A Successful Multifaceted Hospital Wide Hand Hygiene Intervention Based on WHO and Continuous Quality Improvement Methodology
(PLoS, 2012)
Abstract Background: Only multifaceted hospital wide interventions have been successful in achieving sustained improvements ... |
Article
Spanish Multicenter Study of the Epidemiology and Mechanisms of Amoxicillin-Clavulanate Resistance in Escherichia coli
(American Society for Microbiology, 2012)
We conducted a prospective multicenter study in Spain to characterize the mechanisms of resistance to amoxicillin-clavu-lanate ... |
PhD Thesis
Epidemiología clínica, microbiológica y molecular de la bacteriemia por staphylococcus aureus. Impacto de un programa de mejora en el manejo clínico
(2012)
La bacteriemia por S. aureus es una entidad infecciosa de gran relevancia debido a su elevada prevalencia y a que se asocia ... |
Article
Long-term outcome of patients after a single interruption of antiretroviral therapy: a cohort study
(BioMed Central, 2012)
Background: To describe the long term outcome of patients who interrupted highly active antiretroviral therapy (HAART) ... |
Article
β-Lactam/β-Lactam Inhibitor Combinations for the Treatment of Bacteremia Due to Extended-Spectrum β-Lactamase-Producing Escherichia coli: A Post Hoc Analysis of Prospective Cohorts
(Oxford University Press, 2012)
Background. Extended-spectrum ß-lactamase–producing Escherichia coli (ESBL-EC) is an important cause of invasive infections. ... |
Article
Prospective Multicenter Study of the Impact of Carbapenem Resistance on Mortality in Pseudomonas aeruginosa Bloodstream Infections
(American Society for Microbiology, 2012)
The impact of antimicrobial resistance on clinical outcomes is the subject of ongoing investigations, although uncertainty ... |
Article
Virulence Profiles of Bacteremic Extended-Spectrum β-Lactamase-Producing Escherichia coli: Association with Epidemiological and Clinical Features
(Public Library of Science, 2012)
There is scarce data about the importance of phylogroups and virulence factors (VF) in bloodstream infections (BSI) caused ... |
Article
Impact of Inadequate Empirical Therapy on the Mortality of Patients with Bloodstream Infections: a Propensity Score-Based Analysis
(American Society for Microbiology, 2012)
The impact of the adequacy of empirical therapy on outcome for patients with bloodstream infections (BSI) is key for ... |
Article
Programas de optimización de uso de antimicrobianos (PROA) en hospitales españoles: documento de consenso GEIH-SEIMC, SEFH y SEMPSPH
(Elsevier, 2012)
Los antimicrobianos son fármacos distintos al resto. Su eficacia en la reducción de la morbilidad y la mor talidad es muy ... |
Patent. Invention
Dispositivo y método para el estudio dinámico de biocapas sobre catéteres de uso médico
(Oficina Española de Patentes y Marcas (OEPM), 2011)
Dispositivo y método para el estudio dinámico de biocapas sobre catéteres de uso médico. El dispositivo permite la ... |
Article
Klebsiella pneumoniae Strains Producing Extended-Spectrum B-Lactamases in Spain: Microbiological and Clinical Features
(American Society for Microbiology, 2011)
Extended-spectrum B-lactamases (ESBL) of the CTX-M, SHV, and TEM families were recognized in 76 (67%), 31 (27%), and 6 ... |
Article
Biofilm formation at the solid-liquid and air-liquid interfaces by Acinetobacter species
(BioMed Central, 2011)
Abstract Background: The members of the genus Acinetobacter are Gram-negative cocobacilli that are frequently found in the ... |
PhD Thesis
Factores pronósticos de la endorcarditis infecciosa izquierda análisis propensivo sobre el impacto del tratamiento quirúrgico
(2011)
CLa endocarditis infecciosa es infrecuente, pero su mortalidad continúa siendo elevada. En los últimos años esta entidad ... |
PhD Thesis
Factores pronósticos de la endocarditis infecciosa izquierda:Análisis propensivo sobre el impacto del tratamiento quirúrgico
(2011)
Introducción: La endocarditis infecciosa es una enfermedad infecciosa infrecuente pero su mortalidad continua siendo hoy ... |
Article
Clinical Features of Infections and Colonization by Acinetobacter Genospecies 3
(American Society for Microbiology, 2010)
Two hundred twenty-one isolates of Acinetobacter baumannii and 15 of Acinetobacter genospecies 3 (AG3) were consecutively ... |
Article
Epidemiology and clinical features of community-acquired, healthcare-associated and nosocomial bloodstream infections in tertiary-care and community hospitals
(Elsevier, 2010)
Classification of bloodstream infections (BSIs) as community-acquired (CA), healthcare-associated (HCA) and hospital-acquired ... |
Article
Long-Term Control of Endemic Hospital-Wide Methicillin-Resistant Staphylococcus aureus (MRSA): The Impact of Targeted Active Surveillance for MRSA in Patients and Healthcare Workers
(Cambridge University Press, 2010)
To evaluate the long-term impact of successive interventions on rates of methicillin-resistant Staphylococcus aureus (MRSA) ... |
Article
Diversity of Escherichia coli Strains Producing Extended-Spectrum B-Lactamases in Spain: Second Nationwide Study
(American Society for Microbiology, 2010)
The prevalence of extended-spectrum -lactamase (ESBL)-producing Escherichia coli (ESBLEC) in Spain increased 8-fold from ... |
Article
Risk Factors and Prognosis of Nosocomial Bloodstream Infections Caused by Extended-Spectrum-B-Lactamase-Producing Escherichia coli
(American Society for Microbiology, 2010)
Extended-spectrum-B-lactamase (ESBL)-producing Escherichia coli (ESBLEC) is an increasing cause of community and nosocomial ... |
PhD Thesis
Bacteriemias por Escherichia coli productor de beta-lactamasas de espectro extendido epidemiología clínica y molecular
(2010)
Hasta hace poco las infecciones por Escherichia coli productor de BLEE eran infrecuentes, pero en los últimos años estamos ... |
PhD Thesis
Estudio pronóstico de una cohorte de Bacteriemias en función de su adquisición Morbilidad, Mortalidad y Factores Asociados
(2010)
Entre un 0,5% y un 1,3% de los pacientes ingresados en nuestro medio desarrollan un episodio de bacteriemia durante su ... |
Article
Genetic Variability among ampC Genes from Acinetobacter Genomic Species 3
(American Society for Microbiology, 2009)
As a part of a nationwide study in Spain, 15 clinical isolates of Acinetobacter genomic species 3 (AG3) were analyzed. The ... |
| PhD Thesis |
Article
Nosocomial Bacteremia Due to an As Yet Unclassified Acinetobacter Genomic Species 17-Like Strain
(American Society for Microbiology, 2006)
We describe a case of bacteremia due to an as yet unclassified Acinetobacter genomic species 17-like strain. The recognition ... |
Article
Clinical features and epidemiology of acinetobacter baumanni colonization and infection in spanish hospitals
(SLACK, 2004)
OBJECTIVE: To investigate the clinical features and the epidemiology of Acinetobacter baumannii in Spanish hospitals. DESIGN: ... |
Article
Antimicrobial Susceptibility and Mechanisms of Resistance to Quinolones and b-Lactams in Acinetobacter Genospecies 3
(American Society for Microbiology, 2004)
Antimicrobial susceptibility was determined in 15 epidemiologically unrelated clinical isolates of Acinetobacter genospecies ... |
Article
Epidemiology and Clinical Features of Infections Caused by Extended-Spectrum Beta-Lactamase-Producing Escherichia coli in Nonhospitalized Patients
(American Society for Microbiology, 2004)
Infections due to extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli (ESBLEC) in nonhospitalize patients ... |
Article
Type 1 Integrons in Epidemiologically Unrelated Acinetobacter baumannii Isolates Collected at Spanish Hospitals
(American Society for Microbiology, 2004)
|
PhD Thesis
Stenotrophomonas maltophilia: estudio clínico, epidemiológico y pronóstico
(2002)
Stenotrophomonas maltophilia es un patógeno emergente oportunista. Con este trabajo se pretende conocer las características ... |
Article
Genotypic identification of an undescribed spotted fever group rickettsia in ixodes ricinus from southwestern Spain
(American Society of Tropical Medicine and Hygiene, 1998)
An undescribed rickettsia was directly analyzed with specific rickettsial molecular biology tools on Ixodes ricinus L. ... |
PhD Thesis
Interacción de los macrólidos con la actividad de los leucocitos polimorfonucleares humanos
(1996)
Los antimicrobianos, además de su acción antibacteriana directa, pueden tener, en su interacción con las células fagocíticas, ... |