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      Saponin Profile of Wild Asparagus Species 

      Jaramillo Carmona, Sara; Rodríguez Arcos, Rocío; Jiménez Araujo, Ana José; López Martín, Sergio; Gil, Juan; Moreno, Roberto; Guillén Bejarano, Rafael (Wiley, 2017)
      The aim of this work was to study the saponin profiles from spears of different wild asparagus species inthe context of ...
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      Scutoids are a geometrical solution to three-dimensional packing of epithelia 

      Gómez Gálvez, Pedro; Vicente Munuera, Pablo; Tagua Jáñez, Antonio; Forja Barbosa, Cristina; Castro Rodríguez, Ana María; Letrán, Marta; Grima Ruiz, Clara Isabel; Bermúdez Gallardo, Marina; Serrano Pérez-Higueras, Óscar; Márquez Pérez, Alberto; Escudero Cuadrado, Luis María (Nature Publishing Group, 2018)
      As animals develop, tissue bending contributes to shape the organs into complex three-dimensional structures. However, the ...
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      Selective cytotoxic activity and DNA damage by an epoxyalkyl galactopyranoside 

      Burgos Morón, Estefanía; Pastor Carrillo, Nuria María; Orta Vázquez, Manuel Luis; Jiménez Alonso, Julio José; Vega Holm, Margarita; Vega Pérez, José Manuel; Iglesias Guerra, Fernando; Mateos Cordero, Santiago; López Lázaro, Miguel; Calderón Montaño, José Manuel (Wiley, 2018)
      Several clinically useful anticancer drugs selectively kill cancer cells by inducing DNA damage; the genomic instability ...
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      Sensing Cell-Culture Assays with Low-Cost Circuitry 

      Pérez García, Pablo; Huertas Sánchez, Gloria; Maldonado Jacobi, Andrés; Martín Rubio, María Esther; Serrano Viseas, Juan Alfonso; Olmo Fernández, Alberto; Daza Navarro, María Paula; Yúfera García, Alberto (Nature Publishing Group, 2018)
      An alternative approach for cell-culture end-point protocols is proposed herein. This new technique is suitable for real-time ...
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      Sinorhizobium fredii HH103 RirA is required for oxidative stress resistance and efficient symbiosis with Soybean 

      Crespo Rivas, Juan Carlos; Navarro Gómez, Pilar; Alías Villegas, Cynthia; Moreno Onorato, Francisco Javier; Cubo Sánchez, María Teresa; Vinardell González, José María; Ruiz Sainz, José Enrique; Acosta Jurado, Sebastián (MDPI, 2019-02-12)
      Members of Rhizobiaceae contain a homologue of the iron-responsive regulatory protein RirA. In different bacteria, RirA ...
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      Sinorhizobium fredii Strains HH103 and NGR234 Form Nitrogen Fixing Nodules With Diverse Wild Soybeans (Glycine soja) From Central China but Are Ineffective on Northern China Accessions 

      Temprano Vera, Francisco Jesús; Rodríguez Navarro, Dulce Nombre; Acosta Jurado, Sebastián; Navarro Gómez, Pilar; Buendía Clavería, Ana María; Moreno Onorato, Francisco Javier; López Baena, Francisco Javier; Ruiz Sainz, José Enrique; Vinardell González, José María (Frontiers Media, 2018)
      Sinorhizobium fredii indigenous populations are prevalent in provinces of Central China whereas Bradyrhizobium species ...
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      Squalene targets pro- and anti-inflammatory mediators and pathways to modulate over-activation of neutrophils, monocytes and macrophages 

      Cárdeno Galván, Ana; Aparicio Soto, Marina; Montserrat de la Paz, Sergio; Bermúdez Pulgarín, Beatriz; García Muriana, Francisco José; Alarcón de la Lastra Romero, Catalina (Elsevier, 2015)
      Squalene is a natural triterpene consumed as an integral part of the human diet. Increasing evidence demonstrates that ...
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      Structural analysis of the GPI glycan 

      Nakano, Miyako; Sabido Bozo, Susana; Okazaki, Kouta; Aguilera Romero, María Auxiliadora; Rodríguez Gallardo, Sofía; Cortés Gómez, Alejandro; López Martín, Sergio; Ikeda, Atsuko; Funato, Kouichi; Muñiz Guinea, Manuel (PLOS, 2021)
      Glycosylphosphatidylinositol (GPI) anchoring of proteins is an essential post-translational modification in all eukaryotes ...
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      Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy 

      Nguyen, Binh An; Singh, Virender; Afrin, Shumaila; Yakubovska, Anna; Wang, Lanie; Ahmed, Yasmin; González Prieto, Román; Saelices, Lorena (Nature Research, 2024-01-17)
      ATTR amyloidosis is caused by the deposition of transthyretin in the form of amyloid fibrils in virtually every organ of ...
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      SUMO-activated Target Traps (SATTs) Enable the Identification of a Comprehensive E3-specific SUMO Proteome 

      Salas Lloret, Daniel; Jansen, Nicolette S.; Nagamalleswari, Easa; van der Meulen, Coen; Gracheva, Ekaterina; de Ru, Arnoud H.; Otte, H. Anne Marie; van Veelen, Peter A.; Pichler, Andrea; Goedhart, Joachim; Vertegaal, Alfred C.O.; González Prieto, Román (American Association for the Advancement of Science, 2023)
      Ubiquitin and ubiquitin-like conjugation cascades consist of dedicated E1, E2, and E3 enzymes with E3s providing substrate ...
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      The ceramide synthase subunit lac1 regulates cell growth and size in fission yeast 

      Flor Parra, Ignacio; Sabido Bozo, Susana; Ikeda, Atsuko; Hanaoka, Kazuki; Aguilera Romero, María Auxiliadora; Funato, Kouichi; Muñiz Guinea, Manuel; Lucena Hernández, Rafael (Multidisciplinary Digital Publishing Institute (MDPI), 2022)
      Cell division produces two viable cells of a defined size. Thus, all cells require mechanisms to measure growth and trigger ...
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      The Cockayne syndrome protein B is involved in the repair of 5-AZA-2′-deoxycytidine-induced DNA lesions 

      Burgos Morón, Estefanía; Calderón Montaño, José Manuel; Pastor Carrillo, Nuria María; Ruiz Castizo, Ángel; Domínguez García, Inmaculada; López Lázaro, Miguel; Mateos Cordero, Santiago; Orta Vázquez, Manuel Luis (Impact Journals, 2018)
      The Cockayne Syndrome Protein B (CSB) plays an essential role in Transcription-Coupled Nucleotide Excision Repair (TC-NER) ...
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      The complex three-dimensional organization of epithelial tissues 

      Gómez Gálvez, Pedro; Vicente Munuera, Pablo; Anbari, Samira; Buceta, Javier; Escudero Cuadrado, Luis María (The Company of Biologists Ltd., 2021)
      Understanding the cellular organization of tissues is key to developmental biology. In order to deal with this complex ...
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      The effects of exogenous fatty acids and niacin on human monocyte-macrophage plasticity 

      Montserrat de la Paz, Sergio; Rodríguez, Dolores; Cardelo, Magdalena P.; Naranjo, María C.; Bermúdez Pulgarín, Beatriz; Abia González, María del Rocío; García Muriana, Francisco José; López Martín, Sergio (Wiley-Blackwell, 2017)
      Scope: Macrophage plasticity allows adapting to different environments, having a dual activity in inflammatory-related ...
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      The Emp24 complex recruits a specific cargo molecule into endoplasmic reticulum-derived vesicles 

      Muñiz Guinea, Manuel; Nuoffer, Claude; Hauri, Hans Peter; Riezman, Howard (Rockefeller University Press, 2000)
      Members of the yeast p24 family, including Emp24p and Erv25p, form a heteromeric complex re- quired for the efficient ...
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      The p24 Complex Contributes to Specify Arf1 for COPI Coat Selection 

      Sabido Bozo, Susana; Pérez Linero, Ana María; Manzano López, Javier; Rodríguez Gallardo, Sofía; Aguilera Romero, María Auxiliadora; Cortés Gómez, Alejandro; López Martín, Sergio; Wellinger, Ralf Erik; Muñiz Guinea, Manuel (Multidisciplinary Digital Publishing Institute (MDPI), 2021)
      Golgi trafficking depends on the small GTPase Arf1 which, upon activation, drives the assembly of different coats onto ...
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      The P4-ATPase Drs2 Interacts with and Stabilizes the Multisubunit Tethering Complex TRAPPIII in Yeast 

      Pazos, Irene; Puig Tinto, Marta; Betancur, Laura; Cordero, Jorge; Jiménez Menéndez, Nereida; Abella, Marc; Hernandez, Altair C.; Sabido Bozo, Susana; Muñiz Guinea, Manuel; Gallego, Oriol (John Wiley & Sons, 2023)
      Multisubunit Tethering Complexes (MTCs) are a set of conserved protein complexes that tether vesicles at the acceptor ...
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      The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2′-deoxycytidine lesions 

      Orta Vázquez, Manuel Luis; Calderón Montaño, José Manuel; Domínguez García, Inmaculada; Burgos Morón, Estefanía; Pastor Carrillo, Nuria María; López Lázaro, Miguel; Helleday, Thomas (Oxford University Press, 2014)
      Decitabine (5-aza-21-deoxycytidine, 5-azadC) is used in the treatment of Myelodysplatic syndrome (MDS) and Acute Myeloid ...
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      The retrieval function of the KDEL receptor requires PKA phosphorylation of its C-terminus 

      Cabrera Sánchez, Margarita; Muñiz Guinea, Manuel; Hidalgo Jiménez, Josefina; Vega, Lucía; Martín Rubio, María Esther; Velasco López, Ángel (American Society for Cell Biology, 2003)
      The KDEL receptor is a Golgi/intermediate compartment-located integral membrane protein that carries out the retrieval of ...
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      The rkpU gene of Sinorhizobium fredii HH103 is required for bacterial K-antigen polysaccharide production and for efficient nodulation with soybean but not with cowpea 

      Hidalgo Perea, Ángeles; Margaret Oliver, Isabel María; Crespo Rivas, Juan Carlos; Parada Ibáñez, Maribel Eugenia; Murdoch, Piedad del Socorro; López, Abigail; Buendía Clavería, Ana María; Moreno Onorato, Francisco Javier; Gil Serrano, Antonio Miguel; Rodríguez Carvajal, Miguel Ángel; Ruiz Sainz, José Enrique; Vinardell González, José María (Society for General Microbiology, 2010)
      In this work, the role of the rkpU and rkpJ genes in the production of the K-antigen polysaccharides (KPS) and in the ...