Recent Submissions

  • Article
    Icon

    Analysis of serial neuroblastoma PDX passages in mice allows the identification of new mediators of neuroblastoma aggressiveness 

    Gomez Muñoz, Maria De Los Angeles; Aguilar Morante, Diana; Colmenero-Repiso, Ana; Amador Álvarez, Aida; Ojeda-Puertas, Mónica; Cordero Varela, Juan Antonio; Rodríguez-Prieto, Ismael; Pardal Redondo, Ricardo; Vega Moreno, Francisco Manuel (MDPI, 2023-01-13)
    Neuroblastoma is a neural crest cell-derived pediatric tumor characterized by high interand intra-tumor heterogeneity, and ...
  • Article
    Icon

    GPI anchors: Regulated as needed 

    Aguilera Romero, María Auxiliadora; Muñiz Guinea, Manuel (Rockefeller University Press, 2023)
    GPI anchoring is an essential post-translational modification in eukaryotes that links proteins to the plasma membrane. ...
  • Article
    Icon

    Moderate beer consumption and metabolic health: A comprehensive review from the lipoprotein perspective 

    Grao Cruces, Elena; Montserrat de la Paz, Sergio; Martín Rubio, María Esther (Elsevier Science BV, 2022)
    effects on our health. Regarding cardiovascular disease, research needs to consider the amount consumed but also drinking ...
  • Article
    Icon

    XPC–PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair 

    Blessing, Charlotte; Apelt, Katja; Van Den Heuvel, Diana; González Leal, Claudia; Rother, Magdalena B; Van Der Woude, Melanie; González Prieto, Román; Luijsterburg, Martijn S. (Springer Nature, 2022)
    Cells employ global genome nucleotide excision repair (GGR) to eliminate a broad spectrum of DNA lesions, including those ...
  • Article
    Icon

    In vitro toxicity evaluation of graphene oxide and reduced graphene oxide on Caco-2 cells 

    Cebadero Domínguez, Óscar; Ferrández Gómez, B.; Sánchez Ballester, Soraya; Moreno, J.; Jos Gallego, Ángeles Mencía; Cameán Fernández, Ana María (Elsevier, 2022)
    Graphene derivatives are expected to have a great impact in a wide range of applications, among them as food packaging ...
  • Article
    Icon

    El trabajo por proyectos en Educación Secundaria Obligatoria. Una experiencia desde el Departamento de Inglés: My Experience Abroad 

    Daza Navarro, Manuel; Morón Monge, Hortensia; Daza Navarro, María Paula (Universidad Andina Simón Bolívar, 2020-10-09)
    El Aprendizaje Basado en Proyectos (ABP) en el marco de la Enseñanza Secundaria Obligatoria (ESO) presenta nuevos retos a ...
  • Article
    Icon

    Therapeutic Approach to Alzheimer’s Disease: Current Treatments and New Perspectives 

    Pardo Moreno, Teresa; González Acedo, Anabel; Rivas Domínguez, Antonio; García Morales, Victoria; García Cózar, Francisco José; Ramos Rodríguez, Juan José; Melguizo Rodríguez, Lucía (Multidisciplinary Digital Publishing Institute (MDPI), 2022)
    Alzheimer’s disease (AD) is the most common cause of dementia. The pathophysiology of this disease is characterized by the ...
  • Article
    Icon

    Poor Cognitive Agility Conservation in Obese Aging People 

    Pardo Moreno, Teresa; Mohamed Mohamed, Himan; Rivas Domínguez, Antonio; García Morales, Victoria; García Lara, Rubén A.; Suleiman Martos, Sami; Bermúdez Pulgarín, Beatriz; Ramos Rodríguez, Juan José (Multidisciplinary Digital Publishing Institute (MDPI), 2023)
    Life expectancy has been boosted in recent decades at expenses of increasing the age-associated diseases. Dementia, for ...
  • Article
    Icon

    Role of Chromatin Replication in Transcriptional Plasticity, Cell Differentiation and Disease 

    López Jiménez, Elena; González Aguilera, Cristina (Multidisciplinary Digital Publishing Institute (MDPI), 2022)
    Chromatin organization is essential to maintain a correct regulation of gene expression and establish cell identity. ...
  • Article
    Icon

    From Bioimpedance to Volume Estimation: A Model for Edema Calculus in Human Legs 

    Fernandez Scagliusi, Santiago Joaquín; Giménez, Luis; Pérez García, Pablo; Martín Fernández, Daniel; Olmo Fernández, Alberto; Huertas Sánchez, Gloria; Medrano Ortega, Francisco Javier; Yúfera García, Alberto (MDPI, 2023)
    Heart failure (HF) is a severe disease and one of the most important causes of death in our society nowadays. A significant ...
  • Article
    Icon

    Nutritional composition, ultrastructural characterization, and peptidome profile of antioxidant hemp protein hydrolysates 

    Montserrat de la Paz, Sergio; Rivero Pino, Fernando; Villanueva, Álvaro; Toscano Sánchez, María del Rocío; Martín Rubio, María Esther; Millán, Francisco; Millán-Linares, María del Carmen (Elsevier, 2023)
    Hemp is the term commonly used to refer to the variety of Cannabis sativa L. cultivated for industrial purposes. The seeds ...
  • Article
    Icon

    The P4-ATPase Drs2 Interacts with and Stabilizes the Multisubunit Tethering Complex TRAPPIII in Yeast 

    Pazos, Irene; Puig Tinto, Marta; Betancur, Laura; Cordero, Jorge; Jiménez Menéndez, Nereida; Abella, Marc; Hernandez, Altair C.; Sabido Bozo, Susana; Muñiz Guinea, Manuel; Gallego, Oriol (John Wiley & Sons, 2023)
    Multisubunit Tethering Complexes (MTCs) are a set of conserved protein complexes that tether vesicles at the acceptor ...
  • Article
    Icon

    Repeat RNAs associate with replication forks and post-replicative DNA 

    Gylling, Helene M.; González Aguilera, Cristina; Smith, Martin A.; Kaczorowski, Dominik C.; Groth, Anja; Lund, Anders H. (Cold Spring Harbor Laboratory Press, 2020)
    Noncoding RNA has a proven ability to direct and regulate chromatin modifications by acting as scaffolds between DNA and ...
  • Article
    Icon

    MDC1 maintains active elongation complexes of RNA polymerase II 

    Pappas, George; Munk, Sebastian Howen Nesgaard; Watanabe, Kenji; Thomas, Quentin; Gal, Zita; Gram, Helena Hagner; Lee, MyungHee; Gómez Cabello, Daniel; Bartek, Jiri (Elsevier, 2023)
    The role of MDC1 in the DNA damage response has been extensively studied; however, its impact on other cellular processes ...
  • Article
    Icon

    Saponin Profile of Wild Asparagus Species 

    Jaramillo Carmona, Sara; Rodríguez Arcos, Rocío; Jiménez Araujo, Ana José; López Martín, Sergio; Gil, Juan; Moreno, Roberto; Guillén Bejarano, Rafael (Wiley, 2017)
    The aim of this work was to study the saponin profiles from spears of different wild asparagus species inthe context of ...
  • Article
    Icon

    Exogenous fatty acids and niacin on acute prostaglandin D-2 production in human myeloid cells 

    Montserrat de la Paz, Sergio; Bermúdez Pulgarín, Beatriz; López Martín, Sergio; Naranjo, Maria C.; Romero, Yolanda; Bando Hidalgo, María J.; Abia González, María del Rocío; Muriana, Francisco J. G. (Elsevier, 2017)
    Niacin activates HCA2 receptor that results in the release of PGD2. However, little is known on PGD2-producing cells and ...
  • Article
    Icon

    CD4+ and CD8+ T-cell responses in bone marrow to fatty acids in high-fat diets 

    Medrano, Mayte; Lemus Conejo, Ana; López Martín, Sergio; Millán-Linares, María del Carmen; Rosillo Ramírez, María de los Ángeles; Muñiz Guinea, Manuel; Calderón Ruíz, Rocío; Pérez Simón, José Antonio; Abia González, María del Rocío (Elsevier, 2022)
    Obesity is associated with disruptions in the adaptive immune system; however, dietary fatty acids in high-fat diets (HFDs) ...
  • Article
    Icon

    Efficacy of Eribulin Plus Gemcitabine Combination in L-Sarcomas 

    López Álvarez, María; González Aguilera, Cristina; Moura, David S.; Sánchez Bustos, Paloma; Mondaza Hernández, José L.; Martín Ruiz, Marta; Renshaw, Marta; Ramos, Rafael; Castilla, Carolina; Blanco Alcaina, Elena; Hindi, Nadia; Martín Broto, Javier (Multidisciplinary Digital Publishing Institute (MDPI), 2023)
    Although the overall survival of advanced soft-tissue sarcoma (STS) patients has increased in recent years, the median ...
  • Article
    Icon

    RENEB Inter-Laboratory comparison 2017: limits and pitfalls of ILCs 

    Gregoire, Eric; Barquinero, Joan Francesc; Gruel, Gaetan; Benadjaoud, Mohamedamine; Martínez, Juan S.; Beinke, Christina; Domínguez García, Inmaculada; Kulka, Ulrike (Taylor and Francis Group, 2021)
    Abstract Purpose In case of a mass-casualty radiological event, there would be a need for networking to overcome surge ...
  • Article
    Icon

    VCAM-1–targeted MRI Enables Detection of Brain Micrometastases from Different Primary Tumors 

    Cheng, Vinton W.T.; Sarmiento Soto, Manuel; Khrapitchev, Alexandre A.; Pérez Balderas, Francisco; Zakaria, Rasheed; Jenkinson, Michael D.; Middleton, Mark R.; Sibson, Nicola R. (American Association for Cancer Research, 2019)
    Purpose: A major issue for the effective treatment of brain metastasis is the late stage of diagnosis with existing ...

View more