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Artículo
Nutritional composition, ultrastructural characterization, and peptidome profile of antioxidant hemp protein hydrolysates
(Elsevier, 2023)
Hemp is the term commonly used to refer to the variety of Cannabis sativa L. cultivated for industrial purposes. The seeds have gained interest in recent years as functional foods due to their nutritional composition and ...
Artículo
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy
(Nature Research, 2024-01-17)
ATTR amyloidosis is caused by the deposition of transthyretin in the form of amyloid fibrils in virtually every organ of the body, including the heart. This systemic deposition leads to a phenotypic variability that has ...
Artículo
Metabolic Disturbance of High-Saturated Fatty Acid Diet in Cognitive Preservation
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
Aging continues to be the main cause of the development of Alzheimer’s, although it has been described that certain chronic inflammatory pathologies can negatively influence the progress of dementia, including obesity and ...
Artículo
Arginine deprivation alters microglial polarity and synergizes with radiation to eradicate non-arginine-auxotrophic glioblastoma tumors
(American Society for Clinical Investigation, 2022)
New approaches for the management of glioblastoma (GBM) are an urgent and unmet clinical need. Here, we illustrate that the efficacy of radiotherapy for GBM is strikingly potentiated by concomitant therapy with the ...
Artículo
Poor Cognitive Agility Conservation in Obese Aging People
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
Life expectancy has been boosted in recent decades at expenses of increasing the age-associated diseases. Dementia, for its incidence, stands out among the pathologies associated with aging. The exacerbated cognitive ...
Artículo
High-Density Lipoproteins and Mediterranean Diet: A Systematic Review
(MDPI, 2021)
Cardiovascular disease (CVD) is the leading cause of global mortality and the study of high-density lipoproteins (HDL) particle composition and functionality has become a matter of high interest, particularly in light to ...
Artículo
Identification of the Bioavailable Peptidome of Chia Protein Hydrolysate and the In Silico Evaluation of Its Antioxidant and ACE Inhibitory Potential
(American Chemical Society, 2024)
The incorporation of novel, functional, and sustainable foods in human diets is increasing because of their beneficial effects and environmental-friendly nature. Chia (Salvia hispanica L.) has proved to be a suitable ...
Artículo
CartoCell, a high-content pipeline for 3D image analysis, unveils cell morphology patterns in epithelia
(Elsevier, 2023)
Decades of research have not yet fully explained the mechanisms of epithelial self-organization and 3D packing. Single-cell analysis of large 3D epithelial libraries is crucial for understanding the assembly and function ...
Artículo
Impact of Gastrointestinal Digestion In Vitro Procedure on the Characterization and Cytotoxicity of Reduced Graphene Oxide
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
The growing interest in graphene derivatives is a result of their variety of applications in many fields. Due to their use, the oral route could be a potential way of entrance for the general population. This work assesses ...
Artículo
Immediate-release Niacin and a Monounsaturated Fatty Acid-rich Meal on Postprandial Inflammation and Monocyte Characteristics in Men with Metabolic Syndrome
(Elsevier, 2023)
Background & aim: When considered separately, long-term immediate-release niacin and fatty meals enriched in monounsaturated fatty acids (MUFA) decrease postprandial triglycerides, but their effects on postprandial ...