Artículo
Synthesis and cancer growth inhibitory activities of 2-fatty-alkylated pyrrolidine-3,4-diol derivatives
Autor/es | Elías Rodríguez, María del Pilar
Moreno Clavijo, Elena Carrión Jiménez, Sebastián Carmona Asenjo, Ana Teresa Moreno Vargas, Antonio José Caffa, I. Montecucco, F. Cea, M. Nencioni, A. Robina Ramírez, Inmaculada |
Departamento | Universidad de Sevilla. Departamento de Química orgánica |
Fecha de publicación | 2014 |
Fecha de depósito | 2020-06-02 |
Publicado en |
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Resumen | A series of new amphiphilic pyrrolidines containing dodecyl and oleyl apolar side chains were prepared and evaluated for their ability to inhibit the growth of pancreatic ductal adenocarcinoma cells in vitro. The new ... A series of new amphiphilic pyrrolidines containing dodecyl and oleyl apolar side chains were prepared and evaluated for their ability to inhibit the growth of pancreatic ductal adenocarcinoma cells in vitro. The new compounds are shown to exhibit anticancer activity at concentrations in the μM range. |
Cita | Elías Rodríguez, M.d.P., Moreno Clavijo, E., Carrión Jiménez, S., Carmona Asenjo, A.T., Moreno Vargas, A.J., Caffa, I.,...,Robina Ramírez, I. (2014). Synthesis and cancer growth inhibitory activities of 2-fatty-alkylated pyrrolidine-3,4-diol derivatives. Arkivoc, 3, 197-214. |
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