Data

NameRobina Ramírez, Inmaculada
DepartmentQuímica Orgánica
Knowledge areaQuímica Orgánica
Professional categoryCatedrática de Universidad
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    1209

  Publications

 

PhD Thesis
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Síntesis y reactividad de sistemas [2.2.1]bicíclicos. Estudio de la bioconjugación de proteínas con azanorbornadienos

Robina Ramírez, Inmaculada; Moreno Vargas, Antonio José; Gil de Montes Rojas, Enrique (2020-05-24)
En esta Tesis Doctoral se presentan los resultados más relevantes obtenidos del estudio de reactividad llevado a cabo sobre ...
PhD Thesis
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Diseño y síntesis de derivados mono- y multivalentes de 1,4-iminociclitoles: estudio de sus propiedades como inhibidores de glicosidasas.

Carmona Asenjo, Ana Teresa; Moreno Vargas, Antonio José; Robina Ramírez, Inmaculada; Martínez Bailen, Macarena (2019-04-05)
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Azabicyclic vinyl sulfones for residue-specific dual protein labelling

Gil de Montes Rojas, Enrique; Jiménez Moreno, Ester; Oliveira, Bruno L.; Navo, Claudio D.; Robina Ramírez, Inmaculada; Moreno Vargas, Antonio José (Royal Society of Chemistry, 2019-01-01)
We have developed [2.2.1]azabicyclic vinyl sulfone reagents that simultaneously enable cysteine-selective protein modification ...
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Discovery of a Potent α ‑ Galactosidase Inhibitor by in Situ Analysis of a Library of Pyrrolizidine − (Thio)urea Hybrid Molecules Generated via Click Chemistry

Elías Rodríguez, María del Pilar; Pingitore, Valeria; Carmona Asenjo, Ana Teresa; Moreno Vargas, Antonio José; Ide, Daisuke; Miyawaki, Shota; Kato, Atsushi; Álvarez González, Eleuterio; Robina Ramírez, Inmaculada (American Chemical Society, 2018-01-01)
The parallel synthesis of a 26-membered-library of aromatic/aliphatic-(thio)urea-linked pyrrolizidines followed by in ...
PhD Thesis
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Preparación, aplicaciones y reactividad de nuevos derivados de iminoazúcares. Síntesis de análogos del FK866 con propiedades anticáncer

Carmona Asenjo, Ana Teresa; Moreno Vargas, Antonio José; Robina Ramírez, Inmaculada; Elías Rodríguez, María del Pilar (2017-05-23)
En esta Tesis Doctoral se ha desarrollado la síntesis de nuevos (pirrolidín-2-il)-Ctriazoles con configuración L-fuco ...
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Exploring architectures displaying multimeric presentations of a trihydroxypiperidine iminosugar

Matassini, Camilla; Mirabella, Stefania; Goti, Andrea; Robina Ramírez, Inmaculada; Moreno Vargas, Antonio José; Cardona, Francesca (Beilstein-Institut Zur Forderung der Chemischen Wissenschaften, 2015-01-01)
The synthesis of new multivalent architectures based on a trihydroxypiperidine α -fucosidase inhibitor is reported herein. ...
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Gold nanoparticles are suitable cores for building tunable iminosugar multivalency

Matassini, Camilla; Marradi, M.; Cardona, F.; Parmeggiani, C.; Robina Ramírez, Inmaculada; Moreno Vargas, Antonio José; Penadés, S.; Goti, A. (Royal Society of Chemistry: Open Access, 2015-01-01)
The first example of iminosugars multimerization based on gold nanoparticle cores was achieved by a straightforward synthetic ...
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Synthesis and cancer growth inhibitory activities of 2-fatty-alkylated pyrrolidine-3,4-diol derivatives

Elías Rodríguez, María del Pilar; Moreno Clavijo, Elena; Carrión Jiménez, Sebastián; Carmona Asenjo, Ana Teresa; Moreno Vargas, Antonio José; Caffa, I.; Montecucco, F.; Cea, M.; Nencioni, A.; Robina Ramírez, Inmaculada (Arkat USA, 2014-01-01)
A series of new amphiphilic pyrrolidines containing dodecyl and oleyl apolar side chains were prepared and evaluated for ...
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Amine-linked diglycosides: synthesis facilitated by the enhanced reactivity of allylic electrophiles, and glycosidase inhibition assays

Moreno Clavijo, Elena; Cumpstey, Ian; Frigell, Jens; Pershagen, Elias; Akhtar, Tashfeen; Alonzi, Dominic S.; Butters, Terry D.; Robina Ramírez, Inmaculada (2011-01-01)
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Synthesis and Biological Evaluation of Modified 2-Deoxystreptamine Dimers

Coste, G.; Horlacher, T.; Molina Sanz, Lidia; Moreno Vargas, Antonio José; Carmona Asenjo, Ana Teresa; Robina Ramírez, Inmaculada; Seeberger, P.H.; Gerber-Lemaire, S. (Thieme Publishing; Georg Thieme Verlag, 2011-01-01)
Aminoglycosides are powerful antibiotics, but the emergence of resistant bacterial strains has prompted the search for ...
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Monosaccharides and Analogues from Simple Achiral Unsaturated Compounds

Moreno Vargas, Antonio José; Carmona Asenjo, Ana Teresa; Moreno Clavijo, Elena; Robina Ramírez, Inmaculada (Schweizerische Chemische Gesellschaft, 2011-01-01)
We present herein a selection of ingenious methods that have been developed to convert inexpensive furan, pyrrole and unsaturated hydrocarbons into enantiomerically enriched monosaccharides and analogues of biological interest.
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Total asymmetric synthesis of monosaccharides and analogues

Robina Ramírez, Inmaculada; Carmona Asenjo, Ana Teresa; Moreno Vargas, Antonio José; Moreno Clavijo, Elena (Schweizerische Chemische Gesellschaft (Swiss Chemistry Society), 2011-01-01)
Since the discovery of the 'formose reaction' by Butlerow,[1] total synthesis of carbohydrates has undergone rapid ...
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Syntheses and biological activities of 1,4-iminoalditol derivatives as α-L-fucosidase inhibitors

Moreno Clavijo, Elena; Carmona Asenjo, Ana Teresa; Moreno Vargas, Antonio José; Molina Sanz, Lidia; Robina Ramírez, Inmaculada (Schweizerische Chemische Gesellschaft (Swiss Chemistry Society), 2011-01-01)
A review dealing with 1,4-iminoalditol (hydroxylated pyrrolidine) derivatives as inhibitors of α-l-fucosidases including the different synthetic approaches for their preparation as well as their inhibitory properties is presented.
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Synthesis of Novel 3-Amino(Hydroxy)methyl-l-fuco-Azafagomines as Leads for Selective Inhibitors of α-l-Fucosidases

Moreno Clavijo, Elena; Carmona Asenjo, Ana Teresa; Moreno Vargas, Antonio José; Álvarez González, Eleuterio; Robina Ramírez, Inmaculada (2010-01-01)
The synthesis of 3-substituted l-fuco-azafagomines from d-lyxose is reported. They represent the first example of ...
PhD Thesis
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Síntesis estereoselectiva de nuevos furil-aminoácidos y su uso en la preparación de plataformas moleculares y de ligando de biomoléculas

Robina Ramírez, Inmaculada; Moreno Vargas, Antonio José; Carmona Asenjo, Ana Teresa; Molina Sanz, Lidia (2009-03-27)
Los polihidroxialquil-heterociclos son intermedios sintéticos muy interesantes para la preparación de productos de interés ...
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Stereoselective synthesis of chiral furan amino acid analogues of D- and L-serine from D-sugars

Molina, Lidia; Moreno Vargas, Antonio José; Carmona Asenjo, Ana Teresa; Robina Ramírez, Inmaculada (Georg Thieme Verlag, 2006-01-01)
The synthesis of chiral furan amino acid analogues of D - and L -serine is reported. The developed methodology starting ...
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Synthesis of tri- and tetramines containing two 2,3-dihydroxypyrrolidine moieties and their inhibitory activity toward α-mannosidases

Gerber-Lemaire, S.; Popowycz, Florence; Rodríguez García, Eliazar; Schütz, Catherine; Carmona Asenjo, Ana Teresa; Robina Ramírez, Inmaculada; Vogel, Pierre (Arkat USA, 2002-01-01)
Through the reductive amination of N-[(tert-butoxy)carbonyl]-2,5-dideoxy-2, 5-imino-3,4-O-isopropylidene-L-ribose with ...
PhD Thesis
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Sulfoazúcares, sulfoglicolípidos y taurinas N-sustituidas

Fuentes Mota, José; Fernández-Bolaños Guzmán, José María; Robina Ramírez, Inmaculada; Ulgar Ruiz, Víctor Manuel (2001-04-01)
En esta Tesis Doctoral se han preparado C-sulfoazúcares y C-sulfopolioles que contienen un grupo sulfonato (SO3M) en ...
PhD Thesis
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Feniltio y fenilsulfinil glicósidos: síntesis de análogos de factoes Nod y de y de C-sulfocelobiosas

Robina Ramírez, Inmaculada; Fernández-Bolaños Guzmán, José María; Fuentes Mota, José; Gómez Bujedo, Silvia (1999-01-01)
La presente Tesis Doctoral se encuadra dentro de los proyectos de investigación sobre Isotiocianato, tioamnio- y ...
PhD Thesis
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Aminooligosacaridos. Síntesis de glicosilaminas de disacaridos y de lipooligosacaridos

Robina Ramírez, Inmaculada; Fuentes Mota, José; López Barba, Eugenia (1995-10-02)
La presente tesis se ha dividido en dos partes: -reacciones regioselectivas en aminoazucares.En esta parte se han preparado ...