Article
The carotid body, a neurogenic niche in the adult peripheral nervous system
Author/s | Pardal Redondo, Ricardo
![]() ![]() ![]() ![]() ![]() ![]() ![]() Ortega Sáenz, Patricia ![]() ![]() ![]() ![]() ![]() ![]() ![]() Durán, Rocío Platero-Luengo, Aida ![]() ![]() ![]() ![]() ![]() ![]() ![]() López Barneo, José ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
Department | Universidad de Sevilla. Departamento de Fisiología Médica y Biofísica Instituto de Biomedicina de Sevilla (IBIS) |
Publication Date | 2010 |
Deposit Date | 2024-04-04 |
Published in |
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Abstract | We have described a new population of adult neural stem cells residing in the carotid body, a chemoreceptor organ
in the peripheral nervous system. These progenitor cells support neurogenesis in vivo in response to ... We have described a new population of adult neural stem cells residing in the carotid body, a chemoreceptor organ in the peripheral nervous system. These progenitor cells support neurogenesis in vivo in response to physiological stimuli like hypoxemia, and give rise to multipotent neurospheres in culture. Studying the biology of CB stem cells helps to understand the physiological adaptations of the organ, and might shed light on the pathogenesis of CB tumors. Understanding proliferation and differentiation of these cells will enable their use for cell therapy against neurodegenerative diseases. |
Funding agencies | Instituto de Salud Carlos III Marcelino Botin Foundation Spanish Ministry of Science |
Citation | Pardal Redondo, R., Ortega Sáenz, P., Durán, R., Platero-Luengo, A. y López Barneo, J. (2010). The carotid body, a neurogenic niche in the adult peripheral nervous system. Archives italiennes de biologie, 148 (2), 95-105. https://doi.org/10.4449/aib.v148i2.1160. |
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