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  Furin prodomain ppfurin enhances ca2+ entry through orai and trpc6 channels’ activation in breast cancer cells 

  López, Jose J.; Siegfried, Geraldine; Cantonero, Carlos; Soulet, Fabienne; Descarpentrie, Jean; Smani Hajami, Tarik (MDPI, 2021-04-01)

  Furin, a proprotein convertase that belongs to a family of Ca2+-dependent serine peptidases, is involved in the maturation ...

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  Las drogas impactan en los circuitos de recompensa cerebrales y originan depen dencia y adicción, lo que se define actualmente ...

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  Platelet-activating Factor Receptor Initiates Contact of Acinetobacter baumannii Expressing Phosphorylcholine with Host Cells 

  Smani, Younes; Docobo Pérez, Fernando; López Rojas, Rafael; Domínguez Herrera, Juan; Ibáñez Martínez, José; Pachón Díaz, Jerónimo (2012-06)

  Adhesion is an initial and important step in Acinetobacter baumannii causing infections. However, the exact molecular ...

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  The Active and Periactive Zone Organization and the Functional Properties of Small and Large Synapses 

  Cano, Raquel; Tabares Domínguez, Lucía (2016-05-24)

  The arrival of an action potential (AP) at a synaptic terminal elicits highly synchronized quanta release. Repetitive APs ...

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  Fast motor axon loss in SMARD1 does not correspond to morphological and functional alterations of the NMJ 

  Krieger, Frank; Elflein, Nicole; Ruiz Laza, Rocío; Guerra, Joana; Serrano, Antonio L.; Asan, Esther; Tabares, Lucia; Jablonka, Sibylle (Elsevier, 2013-06)

  Spinal muscular atrophy with respiratory distress type 1 (SMARD1) is a childhood motoneuron disease caused by mutations ...

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  In-stent restenosis (ISR) is one of the main limitations of percutaneous coronary intervention (PCI) therapy with drug-eluting ...

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  All living beings undergo systemic physiological decline after ontogeny, characterized as aging. Modern medicine has ...

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  The carotid body: a physiologically relevant germinal niche in the adult peripheral nervous system 

  Sobrino, Verónica; Annese, Valentina; Navarro Guerrero, Elena; Platero-Luengo, Aida; Pardal, Ricardo (Springer, 2018-11-29)

  Oxygen constitutes a vital element for the survival of every single cell in multicellular aerobic organisms like mammals. ...

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  An O-2-sensitive glomus cell-stem cell synapse induces carotid body growth in chronic hipoxia 

  Platero-Luengo, Aida; González-Granero, Susana; Durán Romero, Rocío; Díaz Castro, Blanca; Piruat Palomo, José Ignacio; García-Verdugo, José Manuel; Pardal Redondo, Ricardo; López Barneo, José (CELL PRESS, 2014-01-16)

  Neural stem cells (NSCs) exist in germinal centers of the adult brain and in the carotid body (CB), an oxygen-sensing organ ...

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  Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations 

  Kang, Eunju; Wu, Jun; Martí Gutiérrez, Nuria; Koski, Amy; Tippner-Hedges, Rebecca; Agaronyan, Karen; Platero-Luengo, Aida (Nature Publishing Group, 2016)

  Maternally inherited mitochondrial (mt)DNA mutations can cause fatal or severely debilitating syndromes in children1,2,3, ...

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  More than eighteen years have passed since the first derivation of human embryonic stem cells (ESCs), but their clinical ...

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  Background/Aims: Protein kinase C (PKC)- and RhoA/Rho-associated kinase (ROCK) play important roles in arterial sustained ...

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  Neural stem cells (NSCs) are promising tools for understanding nervous system plasticity and repair, but their use is ...

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  SMN Requirement for Synaptic Vesicle, Active Zone and Microtubule Postnatal Organization in Motor Nerve Terminals 

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  Low levels of the Survival Motor Neuron (SMN) protein produce Spinal Muscular Atrophy (SMA), a severe monogenetic disease ...

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  Hepatitis C virus (HCV) infection has been related to increased risk of development of hepa tocellular carcinoma (HCC) ...

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  Interspecies chimerism with mammalian pluripotent stem cells 

  Wu, Jun; Platero-Luengo, Aida; Sakurai, Masahiro; Sugawara, Atsushi; Gil, María Antonia; Yamauchi, Takayoshi (CELL PRESS, 2017)

  Interspecies blastocyst complementation enables organ-specific enrichment of xenogenic pluripotent stem cell (PSC) ...

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  Neurotransmitter Modulation of Carotid Body Germinal Niche 

  Sobrino, Verónica; Platero-Luengo, Aida; Annese, Valentina; Navarro Guerrero, Elena; González Rodríguez, Patricia; López Barneo, José; Pardal Redondo, Ricardo (MDPI AG, 2020-11-03)

  The carotid body (CB), a neural-crest-derived organ and the main arterial chemoreceptor in mammals, is composed of clusters ...

• Article
  

  Carotid body oxygen sensing and adaptation to hipoxia 

  López Barneo, José; Macías, David; Platero-Luengo, Aida; Ortega Sáenz, Patricia; Pardal Redondo, Ricardo (Springer, 2015-09)

  The carotid body (CB) is the principal arterial chemoreceptor that mediates the hyperventilatory response to hypoxia. Our ...

• Article
  

  Rapamycin restores BDNF-LTP and the persistence of long-term memory in a model of Down's syndrome 

  Andrade-Talavera, Yuniesky; Benito, Itziar; Casañas, Juan José; Rodríguez Moreno, Antonio; Montesinos Gutiérrez, María Luz (Elsevier, 2015)

  Down's syndrome (DS) is the most prevalent genetic intellectual disability. Memory deficits significantly contribute to ...

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