idUS - Author profile: López Barneo, José

Name	López Barneo, José
Department	Fisiología Médica y Biofísica
Knowledge area	Fisiología
Professional category	Profesor Emérito
E-mail	Request

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97
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Article Transgenic NADH dehydrogenase restores oxygen regulation of breathing in mitochondrial complex I-deficient miceTransgenic NADH dehydrogenase restores oxygen regulation of breathing in mitochondrial complex I-deficient mice Jiménez Gómez, Blanca; Jiménez Gómez, Blanca; Ortega Sáenz, Patricia; Ortega Sáenz, Patricia; Gao Chen, Lin; Gao Chen, Lin; González Rodríguez, Patricia; González Rodríguez, Patricia; García-Flores, Paula; García-Flores, Paula; Chandel, Navdeep; Chandel, Navdeep; López Barneo, José; López Barneo, José (NATURE PUBLISHING GROUP, 2023-01-01) The hypoxic ventilatory response (HVR) is a life-saving reflex, triggered by the activation of chemoreceptor glomus cells ...
PhD Thesis Participación de la mitocondria en la biología de los progenitores neurales y la sensibilidad al oxígeno en los quimiorreceptores arterialesParticipación de la mitocondria en la biología de los progenitores neurales y la sensibilidad al oxígeno en los quimiorreceptores arteriales López Barneo, José; López Barneo, José; Muñoz Cabello, Ana María; Muñoz Cabello, Ana María; Cabello Rivera, Daniel; Cabello Rivera, Daniel (2022-01-14) Las mitocondrias son orgánulos que asumen tareas muy diversas y de gran relevancia para la célula eucariota y la homeostasis ...
Article Reduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in miceReduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in mice McElroy, Gregory S.; McElroy, Gregory S.; Chakrabarty, Ram P.; Chakrabarty, Ram P.; D’Alessandro, Karis B.; D’Alessandro, Karis B.; Vasan, Karthik; Vasan, Karthik; Tan, Jerica; Tan, Jerica; Stoolman, Joshua S.; Stoolman, Joshua S.; Gao Chen, Lin; Gao Chen, Lin; López Barneo, José; López Barneo, José; Navdeep S.; Navdeep S. (Nature Publishing Group, 2022-01-01) Aging in mammals leads to reduction in genes encoding the 45-subunit mitochondrial electron transport chain complex I. ...
Article Editorial: Hypoxia and Cardiorespiratory ControlEditorial: Hypoxia and Cardiorespiratory Control Okada, Yasumasa; Okada, Yasumasa; Paton, Julian F.R.; Paton, Julian F.R.; López Barneo, José; López Barneo, José; Wilson, Richard J.A.; Wilson, Richard J.A.; Marina, Nephtali; Marina, Nephtali; Pokorski, Mieczyslaw; Pokorski, Mieczyslaw (Frontiers Media, 2021-12-22) To maintain adequate oxygen levels in the body, which is essential for a healthy life, the respiratory and cardiovascular ...
Article Lactate sensing mechanisms in arterial chemoreceptor cellsLactate sensing mechanisms in arterial chemoreceptor cells Torres-Torrelo, Hortensia; Torres-Torrelo, Hortensia; Ortega Sáenz, Patricia; Ortega Sáenz, Patricia; López Barneo, José; López Barneo, José (2021-01-01) Classically considered a by-product of anaerobic metabolism, lactate is now viewed as a fundamental fuel for oxidative ...
Article Hypoxia compromises the mitochondrial metabolism of Alzheimer’s disease microglia via HIF1Hypoxia compromises the mitochondrial metabolism of Alzheimer’s disease microglia via HIF1 March Diaz, Rosana; March Diaz, Rosana; Lara Ureña, Nieves; Lara Ureña, Nieves; Romero Molina, Carmen; Romero Molina, Carmen; Heras Garvin, Antonio; Heras Garvin, Antonio; Ortega de San Luis, Clara; Ortega de San Luis, Clara; Alvarez Vergara, Maria I.; Alvarez Vergara, Maria I.; Navarro Garrido, Victoria; Navarro Garrido, Victoria; Sánchez Mico, María Victoria; Sánchez Mico, María Victoria; Vizuete Chacón, María Luisa; Vizuete Chacón, María Luisa; López Barneo, José; López Barneo, José; Vitorica Ferrández, Francisco Javier; Vitorica Ferrández, Francisco Javier; Pascual, Alberto; Pascual, Alberto (Springer, 2021-01-01) Genetic Alzheimer’s disease (AD) risk factors associate with reduced defensive amyloid β plaque-associated microglia (AβAM), ...
Article Unexpected obesity, rather than tumorigenesis, in a conditional mouse model of mitochondrial complex II deficiencyUnexpected obesity, rather than tumorigenesis, in a conditional mouse model of mitochondrial complex II deficiency Al Khazal, Fatimah; Al Khazal, Fatimah; Seungwoo, Kang; Seungwoo, Kang; Holte, Molly Nelson; Holte, Molly Nelson; Choi, Doo-Sup; Choi, Doo-Sup; Singh, Ravinder; Singh, Ravinder; Ortega Sáenz, Patricia; Ortega Sáenz, Patricia; López Barneo, José; López Barneo, José; Maher III, James L.; Maher III, James L. (Federation amer soc exp biol, 2021-01-01) Mutations in any of the genes encoding the four subunits of succinate dehydrogenase (SDH), a mitochondrial membrane-bound ...
Article Is Carotid Body Infection Responsible for Silent Hypoxemia in COVID-19 Patients?Is Carotid Body Infection Responsible for Silent Hypoxemia in COVID-19 Patients? Villadiego Luque, Francisco Javier; Villadiego Luque, Francisco Javier; Ramírez Lorca, Reposo; Ramírez Lorca, Reposo; Cala, Fernando; Cala, Fernando; Labandeira-García, José L.; Labandeira-García, José L.; Esteban, Mariano; Esteban, Mariano; Toledo Aral, Juan José; Toledo Aral, Juan José; López Barneo, José; López Barneo, José (Oxford University Press (OUP), 2021-01-01)
Article Using redox-sensitive fluorescent probes to record real-time reactive oxygen species production in cells from mouse carotid body slicesUsing redox-sensitive fluorescent probes to record real-time reactive oxygen species production in cells from mouse carotid body slices Gao Chen, Lin; Gao Chen, Lin; Arias-Mayenco, Ignacio; Arias-Mayenco, Ignacio; Ortega Sáenz, Patricia; Ortega Sáenz, Patricia; López Barneo, José; López Barneo, José (Cell Press, 2021-01-01) Reactive oxygen species (ROS) are important signaling molecules for physiologic processes such as acute response to hypoxia. ...
Article Neurotransmitter Modulation of Carotid Body Germinal NicheNeurotransmitter Modulation of Carotid Body Germinal Niche Sobrino, Verónica; Sobrino, Verónica; Platero-Luengo, Aida; Platero-Luengo, Aida; Annese, Valentina; Annese, Valentina; Navarro Guerrero, Elena; Navarro Guerrero, Elena; González Rodríguez, Patricia; González Rodríguez, Patricia; López Barneo, José; López Barneo, José; Pardal Redondo, Ricardo; Pardal Redondo, Ricardo (MDPI AG, 2020-11-03) The carotid body (CB), a neural-crest-derived organ and the main arterial chemoreceptor in mammals, is composed of clusters ...
PhD Thesis Interneuronas estriatales productoras de GDNF: características moleculares y rol en la neuroprotección catecolaminérgicaInterneuronas estriatales productoras de GDNF: características moleculares y rol en la neuroprotección catecolaminérgica D'Anglemont De Tassigny, Xavier; D'Anglemont De Tassigny, Xavier; López Barneo, José; López Barneo, José; Enterría Morales, Daniel; Enterría Morales, Daniel (2019-05-23)
PhD Thesis Activación de las células glómicas por hipoxia y lactato: el cuerpo carotídeo como sensor metabólico.Activación de las células glómicas por hipoxia y lactato: el cuerpo carotídeo como sensor metabólico. López Barneo, José; López Barneo, José; Ortega Sáenz, Patricia; Ortega Sáenz, Patricia; Torres Torrelo, Hortensia; Torres Torrelo, Hortensia (2019-01-10)
Article HIF-2a is essential for carotid body development and functionHIF-2a is essential for carotid body development and function Macías, David; Macías, David; Cowburn, Andrew S.; Cowburn, Andrew S.; Torres Torrelo, Hortensia; Torres Torrelo, Hortensia; Ortega Sáenz, Patricia; Ortega Sáenz, Patricia; López Barneo, José; López Barneo, José; Johnson, Randall S; Johnson, Randall S (eLife Sciences Publications, 2018-04-19) Mammalian adaptation to oxygen flux occurs at many levels, from shifts in cellular metabolism to physiological adaptations ...
Article Highly efficient neural conversion of human pluripotent stem cells in adherent and animal-free conditionsHighly efficient neural conversion of human pluripotent stem cells in adherent and animal-free conditions Lukovic, Dunja; Lukovic, Dunja; Díez Lloret, Andrea; Díez Lloret, Andrea; Stojkovic, Petra; Stojkovic, Petra; Rodríguez Martínez, Daniel; Rodríguez Martínez, Daniel; Rodríguez Jiménez, Francisco Javier; Rodríguez Jiménez, Francisco Javier; González Rodríguez, P.; González Rodríguez, P.; López Barneo, José; López Barneo, José; Moreno Manzano, Victoria; Moreno Manzano, Victoria; Stojkovic, Miodrag; Stojkovic, Miodrag; Bhattacharya, Shomi S.; Bhattacharya, Shomi S.; Erceg, Slaven; Erceg, Slaven (Wiley, 2017-01-01) Neural differentiation of human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) can produce a ...
Article Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In VivoAcute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In Vivo Serrano Pozo, Alberto; Serrano Pozo, Alberto; Sánchez García, Manuel A.; Sánchez García, Manuel A.; Heras Garvín, Antonio; Heras Garvín, Antonio; March Díaz, Rosana Rocío; March Díaz, Rosana Rocío; Navarro Garrido, Victoria; Navarro Garrido, Victoria; Vizuete Chacón, María Luisa; Vizuete Chacón, María Luisa; López Barneo, José; López Barneo, José; Vitorica Ferrández, Francisco Javier; Vitorica Ferrández, Francisco Javier; Pascual, Alberto; Pascual, Alberto (Public Library of Science, 2017-01-01) Background Recent epidemiological evidence has linked hypoxia with the development of Alzheimer disease (AD). A number ...
Article Striatal GDNF Production Is Independent to Circulating Estradiol Level Despite Pan- Neuronal Activation in the Female Mouse.Striatal GDNF Production Is Independent to Circulating Estradiol Level Despite Pan- Neuronal Activation in the Female Mouse. Enterría Morales, Daniel; Enterría Morales, Daniel; López López, Ivette; López López, Ivette; López Barneo, José; López Barneo, José; D’Anglemont de Tassigny, Xavier; D’Anglemont de Tassigny, Xavier (2016-10-14) Gender difference in Parkinson’s disease (PD) suggests that female sex steroids may promote dopaminergic neuron survival ...
Article Gene expression profiling supports the neural crest origin of adult rodent carotid body stem cells and identifies CD10 as a marker for mesectoderm-committed progenitorsGene expression profiling supports the neural crest origin of adult rodent carotid body stem cells and identifies CD10 as a marker for mesectoderm-committed progenitors Navarro Guerrero, Elena; Navarro Guerrero, Elena; Platero-Luengo, Aida; Platero-Luengo, Aida; Linares Clemente, Pedro; Linares Clemente, Pedro; Cases, Ildefonso; Cases, Ildefonso; López Barneo, José; López Barneo, José; Pardal Redondo, Ricardo; Pardal Redondo, Ricardo (WILEY, 2016-01-01) Neural stem cells (NSCs) are promising tools for understanding nervous system plasticity and repair, but their use is ...
Article Carotid body oxygen sensing and adaptation to hipoxiaCarotid body oxygen sensing and adaptation to hipoxia López Barneo, José; López Barneo, José; Macías, David; Macías, David; Platero-Luengo, Aida; Platero-Luengo, Aida; Ortega Sáenz, Patricia; Ortega Sáenz, Patricia; Pardal Redondo, Ricardo; Pardal Redondo, Ricardo (Springer, 2015-09-01) The carotid body (CB) is the principal arterial chemoreceptor that mediates the hyperventilatory response to hypoxia. Our ...
PhD Thesis Mecanismos moleculares de la sensibilidad aguda al oxígeno en los quimiorreceptores arteriales: función del complejo I mitocondrialMecanismos moleculares de la sensibilidad aguda al oxígeno en los quimiorreceptores arteriales: función del complejo I mitocondrial López Barneo, José; López Barneo, José; Gao Chen, Lin; Gao Chen, Lin; Fernández-Agüera Rodríguez, María del Carmen; Fernández-Agüera Rodríguez, María del Carmen (2015-06-17) El oxígeno (O2) es una molécula esencial para la vida de los animales debido a su metabolismo celular aeróbico, ya que la ...
Article Resistance of subventricular neural stem cells to chronic hypoxemia despite structural disorganization of the germinal center and impairment of neuronal and oligodendrocyte survivalResistance of subventricular neural stem cells to chronic hypoxemia despite structural disorganization of the germinal center and impairment of neuronal and oligodendrocyte survival D'Anglemont De Tassigny, Xavier; D'Anglemont De Tassigny, Xavier; Sirerol-Piquer, M Salomé; Sirerol-Piquer, M Salomé; Gómez-Pinedo, Ulises; Gómez-Pinedo, Ulises; Pardal Redondo, Ricardo; Pardal Redondo, Ricardo; Bonilla, Sonia; Bonilla, Sonia; Capilla González, Vivian; Capilla González, Vivian; López Barneo, José; López Barneo, José (Dove Medical Press Ltd., 2015-01-01) Chronic hypoxemia, as evidenced in de-acclimatized high-altitude residents or in patients with chronic obstructive respiratory ...
PhD Thesis Mecanismos Moleculares de Formación de Tumores en Modelos Genéticos Animales con Defectos Mitocondriales por Deleción del Gen SdhDMecanismos Moleculares de Formación de Tumores en Modelos Genéticos Animales con Defectos Mitocondriales por Deleción del Gen SdhD López Barneo, José; López Barneo, José; Piruat Palomo, José Ignacio; Piruat Palomo, José Ignacio; Millán Uclés, África; Millán Uclés, África (2015-01-01) La disfunción mitocondrial está ampliamente vinculada con la tumorogénesis. Una de las características principales de las ...
Article Glucose sensing by carotid body glomus cells: potential implications in diseaseGlucose sensing by carotid body glomus cells: potential implications in disease Gao Chen, Lin; Gao Chen, Lin; Ortega Sáenz, Patricia; Ortega Sáenz, Patricia; García Fernández, María; García Fernández, María; González Rodríguez, Patricia; González Rodríguez, Patricia; Caballero Eraso, Candela; Caballero Eraso, Candela; López Barneo, José; López Barneo, José (Frontiers Media, 2014-10-15) The carotid body (CB) is a key chemoreceptor organ in which glomus cells sense changes in blood O2, CO2, and pH levels. ...
PhD Thesis Hipertrofia del cuerpo carotídeo en hipoxia crónica: mecanismos de activación, proliferación y diferenciación de los progenitores neurales en el sistema nervioso periféricoHipertrofia del cuerpo carotídeo en hipoxia crónica: mecanismos de activación, proliferación y diferenciación de los progenitores neurales en el sistema nervioso periférico López Barneo, José; López Barneo, José; Pardal Redondo, Ricardo; Pardal Redondo, Ricardo; Platero-Luengo, Aida; Platero-Luengo, Aida (2014-04-25) The goal of this doctoral thesis is to achieve a better understanding of the biology and behavior of the recently discovered ...
Article An O-2-sensitive glomus cell-stem cell synapse induces carotid body growth in chronic hipoxiaAn O-2-sensitive glomus cell-stem cell synapse induces carotid body growth in chronic hipoxia Platero-Luengo, Aida; Platero-Luengo, Aida; González-Granero, Susana; González-Granero, Susana; Durán Romero, Rocío; Durán Romero, Rocío; Díaz Castro, Blanca; Díaz Castro, Blanca; Piruat Palomo, José Ignacio; Piruat Palomo, José Ignacio; García-Verdugo, José Manuel; García-Verdugo, José Manuel; Pardal Redondo, Ricardo; Pardal Redondo, Ricardo; López Barneo, José; López Barneo, José (CELL PRESS, 2014-01-16) Neural stem cells (NSCs) exist in germinal centers of the adult brain and in the carotid body (CB), an oxygen-sensing organ ...
Article A Conditional Mouse Mutant in the Tumor Suppressor SdhD Gene Unveils a Link between p21(WAF1/Cip1) Induction and Mitochondrial DysfunctionA Conditional Mouse Mutant in the Tumor Suppressor SdhD Gene Unveils a Link between p21(WAF1/Cip1) Induction and Mitochondrial Dysfunction Díaz Castro, Blanca; Díaz Castro, Blanca; García Flores, Gloria Paula; García Flores, Gloria Paula; Báez Palomo, Alicia; Báez Palomo, Alicia; Millán Uclés, África; Millán Uclés, África; Pérez Simón, José Antonio; Pérez Simón, José Antonio; Piruat Palomo, José Ignacio; Piruat Palomo, José Ignacio; López Barneo, José; López Barneo, José (2014-01-01)
Article Effect of hypoxia on lung gene expression and proteomic profile: insights into the pulmonary surfactant responseEffect of hypoxia on lung gene expression and proteomic profile: insights into the pulmonary surfactant response Olmeda, Bárbara; Olmeda, Bárbara; Umstead, Todd M.; Umstead, Todd M.; Silveyra, Patricia; Silveyra, Patricia; Pascual Bravo, Alberto; Pascual Bravo, Alberto; López Barneo, José; López Barneo, José; Phelps, David S.; Phelps, David S.; Floros, Joanna; Floros, Joanna; Pérez Gil, Jesús; Pérez Gil, Jesús (Elsevier, 2014-01-01) Exposure of lung to hypoxia has been previously reported to be associated with significant alterations in the protein ...
Article Deletion of the von Hippel-Lindau gene causes sympathoadrenal cell death and impairs chemoreceptor-mediated adaptation to hypoxiaDeletion of the von Hippel-Lindau gene causes sympathoadrenal cell death and impairs chemoreceptor-mediated adaptation to hypoxia Macías, David; Macías, David; Fernández‐Agüera Rodríguez, Mari Carmen; Fernández‐Agüera Rodríguez, Mari Carmen; Bonilla Henao, Victoria; Bonilla Henao, Victoria; López Barneo, José; López Barneo, José (Wiley, 2014-01-01) Mutations of the von Hippel–Lindau (VHL) gene are associated with pheochromocytomas and paragangliomas, but the role of ...
Patent Procedimiento para detectar el precipitado de x-gal u otros precipitados opacos mediante microscopia confocalProcedimiento para detectar el precipitado de x-gal u otros precipitados opacos mediante microscopia confocal Levitsky, Konstantin L.; Levitsky, Konstantin L.; Toledo Aral, Juan José; Toledo Aral, Juan José; López Barneo, José; López Barneo, José (Oficina Española de Patentes y Marcas , 2013-02-27) La presente solicitud de patente se refiere a un procedimiento para la obtención de imágenes confocales de la tinción ...
Article Age-mediated transcriptomic changes in adult mouse substantia nigraAge-mediated transcriptomic changes in adult mouse substantia nigra Gao Chen, Lin; Gao Chen, Lin; Hidalgo-Figueroa, María; Hidalgo-Figueroa, María; Escudero Cuadrado, Luis María; Escudero Cuadrado, Luis María; Díaz Martín, Juan; Díaz Martín, Juan; López Barneo, José; López Barneo, José; Pascual Bravo, Alberto; Pascual Bravo, Alberto (2013-01-01) Substantia nigra pars compacta (SNpc) is highly sensitive to normal aging and selectively degenerates in Parkinson’s disease ...
Article Direct confocal acquisition of fluorescence from X-gal staining on thick tissue sectionsDirect confocal acquisition of fluorescence from X-gal staining on thick tissue sections Levitski, Konstantín; Levitski, Konstantín; Villadiego Luque, Francisco Javier; Villadiego Luque, Francisco Javier; López Barneo, José; López Barneo, José; Toledo Aral, Juan José; Toledo Aral, Juan José (2013-01-01)
Chapter of Book Carotid Body Transplants as a Therapy for Parkinson’s DiseaseCarotid Body Transplants as a Therapy for Parkinson’s Disease Villadiego Luque, Francisco Javier; Villadiego Luque, Francisco Javier; Muñoz Manchado, Ana Belén; Muñoz Manchado, Ana Belén; Méndez Ferrer, Simón; Méndez Ferrer, Simón; Toledo Aral, Juan José; Toledo Aral, Juan José; López Barneo, José; López Barneo, José (The Royal Society of Chemistry, 2013-01-01) Affecting over 1.5 million people across the world, Parkinson's disease is a progressive neurological condition characterized, ...
Article ¿Qué nos enseñan los modelos animales y celulares sobre la enfermedad de Parkinson?¿Qué nos enseñan los modelos animales y celulares sobre la enfermedad de Parkinson? López Barneo, José; López Barneo, José (2013-01-01)
Article Prolyl Hydroxylase-dependent Modulation of Eukaryotic Elongation Factor 2 Activity and Protein Translation under Acute HypoxiaProlyl Hydroxylase-dependent Modulation of Eukaryotic Elongation Factor 2 Activity and Protein Translation under Acute Hypoxia Romero-Ruiz, Antonio; Romero-Ruiz, Antonio; Bautista, Lucía; Bautista, Lucía; Navarro, Virginia; Navarro, Virginia; Heras Garvín, Antonio; Heras Garvín, Antonio; Castellano Orozco, Antonio Gonzalo; Castellano Orozco, Antonio Gonzalo; López Barneo, José; López Barneo, José; Pascual, Alberto; Pascual, Alberto (American Society for Biochemistry and Molecular Biology, 2012-02-03) Early adaptive responses to hypoxia are essential for cell survival, but their nature and underlying mechanisms are poorly ...
PhD Thesis Generación y análisis del ratón mutante condicional en la subunidad D del complejo II mitocondrial: efecto sobre el sistema nervioso central y el periféricoGeneración y análisis del ratón mutante condicional en la subunidad D del complejo II mitocondrial: efecto sobre el sistema nervioso central y el periférico López Barneo, José; López Barneo, José; Piruat Palomo, José Ignacio; Piruat Palomo, José Ignacio; Díaz Castro, Blanca; Díaz Castro, Blanca (2012-01-01) SDHD es un gen supresor de tumores en humanos. Este gen codifica para una (SDHD) de las cuatro proteínas que forman parte ...
Article Differential impairment of catecholaminergic cell maturation and survival by genetic mitochondrial complex II dysfunctionDifferential impairment of catecholaminergic cell maturation and survival by genetic mitochondrial complex II dysfunction Díaz Castro, Blanca; Díaz Castro, Blanca; Pintado, Carmelo Oscar; Pintado, Carmelo Oscar; García Flores, Gloria Paula; García Flores, Gloria Paula; López Barneo, José; López Barneo, José; Piruat Palomo, José Ignacio; Piruat Palomo, José Ignacio (2012-01-01) The SDHD gene (subunit D of succinate dehydrogenase) has been shown to be involved in the generation of paragangliomas and ...
Article T-type Ca2+ channels in mouse embryonic stem cells: modulation during cell cycle and contribution to self-renewalT-type Ca2+ channels in mouse embryonic stem cells: modulation during cell cycle and contribution to self-renewal Rodríguez Gómez, José Antonio; Rodríguez Gómez, José Antonio; Levitski, Konstantín; Levitski, Konstantín; López Barneo, José; López Barneo, José (2012-01-01)
Article GDNF Is predominantly expressed in the PV+ neostriatal interneuronal ensemble in normal mouse and after Injury of the nigrostriatal pathwayGDNF Is predominantly expressed in the PV+ neostriatal interneuronal ensemble in normal mouse and after Injury of the nigrostriatal pathway Hidalgo-Figueroa, María; Hidalgo-Figueroa, María; Bonilla Jiménez, Sonia; Bonilla Jiménez, Sonia; Gutiérrez, Francisco; Gutiérrez, Francisco; Pascual Bravo, Alberto; Pascual Bravo, Alberto; López Barneo, José; López Barneo, José (2012-01-01) Glial cell line-derived neurotrophic factor (GDNF) is absolutely required for survival of dopaminergic (DA) nigrostriatal ...
PhD Thesis Participación de hemoproteínas en la función uimiosensora de células neurosecretorasParticipación de hemoproteínas en la función uimiosensora de células neurosecretoras López Barneo, José; López Barneo, José; Pascual Bravo, Alberto; Pascual Bravo, Alberto; Marcos Almaraz, María Teresa; Marcos Almaraz, María Teresa (2011-09-26) En los mamíferos existe un sistema homeostático de tejidos con células sensibles a las variaciones en los niveles sanguíneos ...
Chapter of Book Neuroprotection in Parkinson’s DiseaseNeuroprotection in Parkinson’s Disease Pascual Bravo, Alberto; Pascual Bravo, Alberto; Villadiego Luque, Francisco Javier; Villadiego Luque, Francisco Javier; Hidalgo-Figueroa, María; Hidalgo-Figueroa, María; Méndez Ferrer, Simón; Méndez Ferrer, Simón; Gómez Díaz, Raquel; Gómez Díaz, Raquel; Toledo Aral, Juan José; Toledo Aral, Juan José; López Barneo, José; López Barneo, José (Royal Society of Chemistry, 2011-01-01)
Article Functional and transcriptional induction of Aquaporin-1 gene by hypoxia; analysis of promoter and role of Hif-1αFunctional and transcriptional induction of Aquaporin-1 gene by hypoxia; analysis of promoter and role of Hif-1α Abreu Rodríguez, Irene; Abreu Rodríguez, Irene; Sánchez Silva, Rocío; Sánchez Silva, Rocío; Martins, Ana Paula; Martins, Ana Paula; Soveral, Graça; Soveral, Graça; Toledo Aral, Juan José; Toledo Aral, Juan José; López Barneo, José; López Barneo, José; Echevarría Irusta, Miriam; Echevarría Irusta, Miriam (2011-01-01) Aquaporin-1 (AQP1) is a water channel that is highly expressed in tissues with rapid O2 transport. It has been reported ...
Chapter of Book La fisiología celular, los canales iónicos y la creación de una biofísica españolaLa fisiología celular, los canales iónicos y la creación de una biofísica española López Barneo, José; López Barneo, José (Manuel Cortijo Mérida, 2011-01-01)
Chapter of Book Clinical applications of cell therapyClinical applications of cell therapy López Barneo, José; López Barneo, José (Edikamed, 2010-01-01)
Article Carotid body chemosensory responses in mice deficient of TASK channelsCarotid body chemosensory responses in mice deficient of TASK channels Ortega Sáenz, Patricia; Ortega Sáenz, Patricia; Levitski, Konstantín; Levitski, Konstantín; Marcos Almaraz, María Teresa; Marcos Almaraz, María Teresa; Bonilla Henao, Victoria; Bonilla Henao, Victoria; Pascual Bravo, Alberto; Pascual Bravo, Alberto; López Barneo, José; López Barneo, José (2010-01-01) Background K+ channels of the TASK family are believed to participate in sensory transduction by chemoreceptor (glomus) ...
Article First aid kit for hypoxic survival: sensors and strategiesFirst aid kit for hypoxic survival: sensors and strategies López Barneo, José; López Barneo, José; Nurse, C.A.; Nurse, C.A.; Nilsson, G.E.; Nilsson, G.E.; Buck, L.T.; Buck, L.T.; Gassmann, M.; Gassmann, M.; Bogdanova, A. Yu.; Bogdanova, A. Yu. (University of Chicago Press, 2010-01-01) Survival success under conditions of acute oxygen deprivation depends on efficiency of the central and peripheral ...
Patent Células madre derivadas del cuerpo carotideo y usos de las mismasCélulas madre derivadas del cuerpo carotideo y usos de las mismas Durán, Rocío; Durán, Rocío; López Barneo, José; López Barneo, José; Pardal, Ricardo; Pardal, Ricardo; Ortega Sáenz, Patricia; Ortega Sáenz, Patricia (Oficina Española de Patentes y Marcas , 2009-09-30) Células madre derivadas del cuerpo carotídeo y usos de las mismas caracterizadas porque son positivas para el marcador ...
PhD Thesis Hipoxia en cardiomiocitos; regulación de la expresión de la subunidad b1 del canal maxi-k y participación en el precondicionamiento cardíacoHipoxia en cardiomiocitos; regulación de la expresión de la subunidad b1 del canal maxi-k y participación en el precondicionamiento cardíaco Castellano Orozco, Antonio Gonzalo; Castellano Orozco, Antonio Gonzalo; López Barneo, José; López Barneo, José; Bautista Borrego, Lucía; Bautista Borrego, Lucía (2009-03-09) The presence of maxi-K channels has been reported in the mitochondria of the cardiac myocytes where it plays a cytoprotective ...
Article Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- miceAbnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice Bishop, Tammie; Bishop, Tammie; Gallagher, Denis; Gallagher, Denis; Pascual Bravo, Alberto; Pascual Bravo, Alberto; Lygate, Craig A.; Lygate, Craig A.; Bono, Joseph P. de; Bono, Joseph P. de; Nicholls, Lynn G.; Nicholls, Lynn G.; Ortega Sáenz, Patricia; Ortega Sáenz, Patricia; Oster, Henrik; Oster, Henrik; Wijeyekoon, Bhathiya; Wijeyekoon, Bhathiya; Sutherland, Andrew I.; Sutherland, Andrew I.; Grosfeld, Alexandra; Grosfeld, Alexandra; Aragones, Julian; Aragones, Julian; Schneider, Martin; Schneider, Martin; Geyte, Katie van; Geyte, Katie van; Teixeira, Dania; Teixeira, Dania; Diez Juan, Antonio; Diez Juan, Antonio; López Barneo, José; López Barneo, José; Channon, Keith M.; Channon, Keith M.; Maxwell, Patrick H.; Maxwell, Patrick H.; Pugh, Christopher W.; Pugh, Christopher W.; Davies, Alun M.; Davies, Alun M.; Carmeliet, Peter; Carmeliet, Peter; Ratcliffe, Peter J.; Ratcliffe, Peter J. (2008-01-01) Cell culture studies have implicated the oxygen-sensitive hypoxia-inducible factor (HIF) prolyl hydroxylase PHD3 in the ...
PhD Thesis GDNF y cuerpo carotídeo: implicaciones funcionales y uso en terapia celularGDNF y cuerpo carotídeo: implicaciones funcionales y uso en terapia celular López Barneo, José; López Barneo, José; Toledo Aral, Juan José; Toledo Aral, Juan José; Villadiego Luque, Francisco Javier; Villadiego Luque, Francisco Javier (2007-04-19) El proyecto que se desarrolla en esta Tesis Doctoral se ha centrado en el estudio de los mecanismos celulares y moleculares ...
PhD Thesis Quimiorrecepción del CO2 en la médula adrenal y facilitación de la permeabilidad a O2 por la acuaporina-1Quimiorrecepción del CO2 en la médula adrenal y facilitación de la permeabilidad a O2 por la acuaporina-1 Echevarría Irusta, Miriam; Echevarría Irusta, Miriam; López Barneo, José; López Barneo, José; Toledo Aral, Juan José; Toledo Aral, Juan José; Muñoz Cabello, Ana María; Muñoz Cabello, Ana María (2007-02-02) El desarrollo de esta Tesis se ha centrado en el estudio de los mecanismos celulares que permiten la quimiotransducción ...
PhD Thesis Neuroprotección en un nuevo modelo de animal transgénicoNeuroprotección en un nuevo modelo de animal transgénico Echevarría Irusta, Miriam; Echevarría Irusta, Miriam; López Barneo, José; López Barneo, José; Mejías Estévez, Rebeca María; Mejías Estévez, Rebeca María (2006-06-20) El objetivo general de este proyecto fue analizar en un modelo de parkinsonismo experimental en ratones, si el aumento del ...
PhD Thesis Acoplamiento excitación-contracción en músculo liso: nuevo papel metabotrópico de los canales de calcio en la regulación del tono vascularAcoplamiento excitación-contracción en músculo liso: nuevo papel metabotrópico de los canales de calcio en la regulación del tono vascular López Barneo, José; López Barneo, José; Ureña López, Juan; Ureña López, Juan; Valle Rodríguez, Alberto del; Valle Rodríguez, Alberto del (2006-01-17) El músculo liso es un tejido que se encuentra generalmente recubriendo órganos (músculo liso visceral: tubo digestivo, ...
Article Acute oxygen sensing in heme oxygenase-2 null miceAcute oxygen sensing in heme oxygenase-2 null mice Ortega Sáenz, Patricia; Ortega Sáenz, Patricia; López Barneo, José; López Barneo, José; Pascual Bravo, Alberto; Pascual Bravo, Alberto; Gómez Díaz, Raquel; Gómez Díaz, Raquel (2006-01-01) Hemeoxygenase-2 (HO-2) is an antioxidant enzyme that can modulate recombinant maxi-K+ channels and has been proposed to ...
Article Metabotropic Ca2+ channel-induced Ca2+ release and ATP-dependent facilitation of arterial myocyte contractionMetabotropic Ca2+ channel-induced Ca2+ release and ATP-dependent facilitation of arterial myocyte contraction Valle Rodríguez, Alberto del; Valle Rodríguez, Alberto del; Calderón Sánchez, Eva María; Calderón Sánchez, Eva María; Ruiz Pérez, Myriam; Ruiz Pérez, Myriam; Ordóñez Guerrero, Antonio; Ordóñez Guerrero, Antonio; López Barneo, José; López Barneo, José; Ureña López, Juan; Ureña López, Juan (2006-01-01) Voltage-gated Ca2_ channels in arterial myocytes can mediate Ca2_ release from the sarcoplasmic reticulum and, thus, induce ...
Presentation Oxygen-sensing by ion channels and mitochondrial function in carotid body glomus cellsOxygen-sensing by ion channels and mitochondrial function in carotid body glomus cells López Barneo, José; López Barneo, José; Ortega Sáenz, Patricia; Ortega Sáenz, Patricia; Piruat Palomo, José Ignacio; Piruat Palomo, José Ignacio; García Fernández, María; García Fernández, María (John Wiley & Sons, 2006-01-01) Carotid body glomus cells release transmitters in response to hypoxia due to the increase of excitability resulting from ...
PhD Thesis Regulación de la expresión génica de canales iónicos por hipoxia crónica en células cromafinesRegulación de la expresión génica de canales iónicos por hipoxia crónica en células cromafines Chiara, María D.; Chiara, María D.; López Barneo, José; López Barneo, José; Toro Estévez, Raquel del; Toro Estévez, Raquel del (2005-12-12) El objetivo general de este proyecto fue el estudio de la regulación por hipoxia de la expresión de genes que codifican ...
PhD Thesis Células neurosecretoras sensoras de oxígeno y glucosaCélulas neurosecretoras sensoras de oxígeno y glucosa López Barneo, José; López Barneo, José; Ortega Sáenz, Patricia; Ortega Sáenz, Patricia; García Fernández, María; García Fernández, María (2005-04-20) El mantenimiento de un medio interno estable, u homesotasia, es especial para los seres vivos. Por ello existen sistemas ...
Article Selective Glial Cell Line-Derived Neurotrophic Factor Production in Adult Dopaminergic Carotid Body Cells In Situ and after Intrastriatal TransplantationSelective Glial Cell Line-Derived Neurotrophic Factor Production in Adult Dopaminergic Carotid Body Cells In Situ and after Intrastriatal Transplantation Villadiego Luque, Francisco Javier; Villadiego Luque, Francisco Javier; Méndez Ferrer, Simón; Méndez Ferrer, Simón; Valdés Sánchez, Teresa; Valdés Sánchez, Teresa; Silos Santiago, Inmaculada; Silos Santiago, Inmaculada; Fariñas, Isabel; Fariñas, Isabel; López Barneo, José; López Barneo, José; Toledo Aral, Juan José; Toledo Aral, Juan José (2005-01-01) Glial cell line-derived neurotrophic factor (GDNF) exerts a notable protective effect on dopaminergic neurons in rodent ...
Article Rat Adrenal Chromaffin Cells Are Neonatal CO2 SensorsRat Adrenal Chromaffin Cells Are Neonatal CO2 Sensors Muñoz Cabello, Ana María; Muñoz Cabello, Ana María; Toledo Aral, Juan José; Toledo Aral, Juan José; López Barneo, José; López Barneo, José; Echevarría Irusta, Miriam; Echevarría Irusta, Miriam (2005-01-01) We studied the participation of adrenal medulla (AM) chromaffin cells in hypercapnic chemotransduction. Using amperometric ...
Article Acute Oxygen-Sensing MechanismsAcute Oxygen-Sensing Mechanisms Kenneth E., Weir; Kenneth E., Weir; López Barneo, José; López Barneo, José; Buckler, Keith J.; Buckler, Keith J.; Archer, Stephen L.; Archer, Stephen L. (2005-01-01)
Article MECHANISMS OF DISEASE Acute Oxygen-Sensing MechanismsMECHANISMS OF DISEASE Acute Oxygen-Sensing Mechanisms E. Kenneth Weir, M.D.; E. Kenneth Weir, M.D.; López Barneo, José; López Barneo, José; Buckler, Keith J.; Buckler, Keith J.; Stephen L. Archer, M.D; Stephen L. Archer, M.D (Massachusetts Medical Society, 2005-01-01) JOSEPH PRIESTLEY, ONE OF THE THREE SCIENTISTS CREDITED WITH THE discovery of oxygen, described the death of mice that were ...
Article Multiple Facets of Maxi-K Channels: The Heme ConnectionMultiple Facets of Maxi-K Channels: The Heme Connection López Barneo, José; López Barneo, José; Castellano Orozco, Antonio Gonzalo; Castellano Orozco, Antonio Gonzalo (2005-01-01)
Article Regulation of oxygen sensing by ion channelsRegulation of oxygen sensing by ion channels López Barneo, José; López Barneo, José; Toro Estévez, Raquel del; Toro Estévez, Raquel del; Levitski, Konstantín; Levitski, Konstantín; Chiara, María D.; Chiara, María D.; Ortega Sáenz, Patricia; Ortega Sáenz, Patricia (2004-01-01) O2 sensing is of critical importance for cell survival and adaptation of living organisms to changing environments or ...
Article The Mitochondrial SDHD Gene Is Required for Early Embryogenesis, and Its Partial Deficiency Results in Persistent Carotid Body Glomus Cell Activation with Full Responsiveness to HypoxiaThe Mitochondrial SDHD Gene Is Required for Early Embryogenesis, and Its Partial Deficiency Results in Persistent Carotid Body Glomus Cell Activation with Full Responsiveness to Hypoxia Piruat Palomo, José Ignacio; Piruat Palomo, José Ignacio; Óscar Pintado, Carmelo; Óscar Pintado, Carmelo; Ortega Sáenz, Patricia; Ortega Sáenz, Patricia; Roche Molina, Marta; Roche Molina, Marta; López Barneo, José; López Barneo, José (2004-01-01) The SDHD gene encodes one of the two membrane-anchoring proteins of the succinate dehydrogenase (complex II) of the ...
Article Rotenone selectively occludes sensitivity to hypoxia in rat carotid body glomus cellsRotenone selectively occludes sensitivity to hypoxia in rat carotid body glomus cells Ortega Sáenz, Patricia; Ortega Sáenz, Patricia; Pardal Redondo, Ricardo; Pardal Redondo, Ricardo; García Fernández, María; García Fernández, María; López Barneo, José; López Barneo, José (Wiley-Blackwell Publishing Ltd., 2003-01-01) Carotid body glomus cells release transmitters in response to hypoxia due to the increase of excitability resulting from ...
Article Trophic restoration of the nigrostriatal dopaminergic pathway in long-term carotid body-grafted parkinsonian ratsTrophic restoration of the nigrostriatal dopaminergic pathway in long-term carotid body-grafted parkinsonian rats Toledo Aral, Juan José; Toledo Aral, Juan José; Méndez Ferrer, Simón; Méndez Ferrer, Simón; Pardal Redondo, Ricardo; Pardal Redondo, Ricardo; Echevarría Irusta, Miriam; Echevarría Irusta, Miriam; López Barneo, José; López Barneo, José (2003-01-01) We studied the mechanisms underlying long-term functional recovery of hemiparkinsonian rats grafted intrastriatally with ...
PhD Thesis Sensibilidad a hipoxia e hipoglucemia de células glómicas en rodajas de cuerpo carotídeoSensibilidad a hipoxia e hipoglucemia de células glómicas en rodajas de cuerpo carotídeo López Barneo, José; López Barneo, José; Pardal Redondo, Ricardo; Pardal Redondo, Ricardo (2000-12-04) Los objetivos generales del presente trabajo fueron los siguientes: 1. Puesta a punto de la preparación de rodajas finas ...
PhD Thesis Homeostasis del calcio en miocitos del árbol arterial pulmonarHomeostasis del calcio en miocitos del árbol arterial pulmonar López Barneo, José; López Barneo, José; Ureña López, Juan; Ureña López, Juan; Smani Hajami, Tarik; Smani Hajami, Tarik (2000-07-24) En el presente trabajo se ha estudiado la homeostasis de la (Ca2+) i en miocitos aislados de la arteria pulmonar y el ...
Article Collapse of conductance Is prevented by a Glutamate residue conserved in voltage-dependent K+ channelsCollapse of conductance Is prevented by a Glutamate residue conserved in voltage-dependent K+ channels Ortega Sáenz, Patricia; Ortega Sáenz, Patricia; Pardal Redondo, Ricardo; Pardal Redondo, Ricardo; Castellano Orozco, Antonio Gonzalo; Castellano Orozco, Antonio Gonzalo; López Barneo, José; López Barneo, José (2000-01-01) Voltage-dependent K 1 channel gating is influenced by the permeating ions. Extracellular K 1 determines the occupation of ...
Article Secretory responses of intact glomus cells in thin slices of rat carotid body to hypoxia and tetraethylammoniumSecretory responses of intact glomus cells in thin slices of rat carotid body to hypoxia and tetraethylammonium Pardal Redondo, Ricardo; Pardal Redondo, Ricardo; Ludewig, Uwe; Ludewig, Uwe; García Hirschfeld, Julia; García Hirschfeld, Julia; López Barneo, José; López Barneo, José (2000-01-01) We have developed a thin-slice preparation of whole rat carotid body that allows us to perform patch-clamp recording of ...
PhD Thesis Subunidades α-reguladoras de canales K+; determinantes moleculares de la función Kv2.3Subunidades α-reguladoras de canales K+; determinantes moleculares de la función Kv2.3 López Barneo, José; López Barneo, José; Chiara, María D.; Chiara, María D.; Monje Quiroga, Francisco; Monje Quiroga, Francisco (1999-05-10)
Article Evolución a largo plazo de trasplantes de cuerpo carotídeo en el estriado de ratas hemiparkinsonianas [Reseñas]Evolución a largo plazo de trasplantes de cuerpo carotídeo en el estriado de ratas hemiparkinsonianas [Reseñas] Pardal Redondo, Ricardo; Pardal Redondo, Ricardo; Toledo Aral, Juan José; Toledo Aral, Juan José; Montoro, R.J.; Montoro, R.J.; Méndez Ferrer, Simón; Méndez Ferrer, Simón; Fernández-Espejo, Emilio; Fernández-Espejo, Emilio; Armengol Butrón de Mújica, José Ángel; Armengol Butrón de Mújica, José Ángel; Herrero, M.T.; Herrero, M.T.; Nieto, M.A.; Nieto, M.A.; López Barneo, José; López Barneo, José (1999-01-01)
Article A Small Domain in the N Terminus of the Regulatory a-Subunit Kv2.3 Modulates Kv2.1 Potassium Channel GatingA Small Domain in the N Terminus of the Regulatory a-Subunit Kv2.3 Modulates Kv2.1 Potassium Channel Gating Chiara, María D.; Chiara, María D.; Monje Quiroga, Francisco; Monje Quiroga, Francisco; Castellano Orozco, Antonio Gonzalo; Castellano Orozco, Antonio Gonzalo; López Barneo, José; López Barneo, José (1999-01-01) Recent work has demonstrated the existence of regulatory K1 channel a-subunits that are electrically silent but capable ...
PhD Thesis Regulación estructural y funcional de canales de K+ por mutaciones en el poro y una subunidad alfa reguladoraRegulación estructural y funcional de canales de K+ por mutaciones en el poro y una subunidad alfa reguladora López Barneo, José; López Barneo, José; Molina Pachón, Antonio; Molina Pachón, Antonio (1997-02-07)
Article Identification and Functional Characterization of a K1 Channel a- Subunit with Regulatory Properties Specific to BrainIdentification and Functional Characterization of a K1 Channel a- Subunit with Regulatory Properties Specific to Brain Castellano Orozco, Antonio Gonzalo; Castellano Orozco, Antonio Gonzalo; Chiara, María D.; Chiara, María D.; Mellström, Britt; Mellström, Britt; Molina, Antonio; Molina, Antonio; Monje Quiroga, Francisco; Monje Quiroga, Francisco; Naranjo, José R.; Naranjo, José R.; López Barneo, José; López Barneo, José (1997-01-01) The physiological diversity of K1 channels mainly depends on the expression of several genes encoding different a-subunits. ...
Article Oxygen sensing by ion channels and chemotransduction in single glomus cellsOxygen sensing by ion channels and chemotransduction in single glomus cells López Barneo, José; López Barneo, José; Montoro Laseca, Rafael Jesús; Montoro Laseca, Rafael Jesús; Ureña López, Juan; Ureña López, Juan; Fernández-Chacón, Rafael; Fernández-Chacón, Rafael; Álvarez de Toledo Naranjo, Guillermo; Álvarez de Toledo Naranjo, Guillermo (1996-01-01) We have monitored cytosolic [Ca2+] and dopamine release in intact fura-2-loaded glomus cells with microfluoroimetry and a ...
Article Oxygen-sensitive calcium channels in vascular smooth muscle and their possible role in hypoxic arterial relaxationOxygen-sensitive calcium channels in vascular smooth muscle and their possible role in hypoxic arterial relaxation Franco Obregón, Alfredo; Franco Obregón, Alfredo; Ureña López, Juan; Ureña López, Juan; López Barneo, José; López Barneo, José (1995-01-01) We have investigated the modifications of cytosolic [Ca2+] and the activity of Ca2+ channels in freshly dispersed arterial ...
Article Hypoxia induces voltage-dependent Ca2+ entry and quantal dopamine secretion in carotid body glomus cellsHypoxia induces voltage-dependent Ca2+ entry and quantal dopamine secretion in carotid body glomus cells Ureña López, Juan; Ureña López, Juan; Fernández-Chacón, Rafael; Fernández-Chacón, Rafael; Rodríguez Benot, Alberto; Rodríguez Benot, Alberto; Álvarez de Toledo Naranjo, Guillermo; Álvarez de Toledo Naranjo, Guillermo; López Barneo, José; López Barneo, José (1994-01-01) We have investigated the changes of cytosolic [Ca2+1 and the secretory -activity in single glomus cells dispersed from ...
PhD Thesis Adaptación y modificaciones de corta y larga duración en la actividad eléctrica de neuronas de la corteza cerebral in vitroAdaptación y modificaciones de corta y larga duración en la actividad eléctrica de neuronas de la corteza cerebral in vitro López Barneo, José; López Barneo, José; Montoro Laseca, Rafael Jesús; Montoro Laseca, Rafael Jesús (1993-03-04) El sistema nervioso central lleva a cabo sus complejas funciones gracias a la actividad armónica de sus unidades básicas, ...
Article Gating of O2-sensitive K + Channels of Arterial Chemoreceptor Cells and Kinetic Modifications Induced by Low PO2Gating of O2-sensitive K + Channels of Arterial Chemoreceptor Cells and Kinetic Modifications Induced by Low PO2 Ganfornina, María Dolores; Ganfornina, María Dolores; López Barneo, José; López Barneo, José (1992-01-01) We have studied the kinetic properties of the O2-sensitive K+ channels (KO2 channels) of dissociated glomus cells from ...
Article Potassium Channel Types in Arterial Chemoreceptor Cells and Their Selective Modulation by OxygenPotassium Channel Types in Arterial Chemoreceptor Cells and Their Selective Modulation by Oxygen Ganfornina, María Dolores; Ganfornina, María Dolores; López Barneo, José; López Barneo, José (1992-01-01) Single K+ channel currents were recorded in excised membrane patches from dispersed chemoreceptor cells of the rabbit ...
PhD Thesis Canales de calcio de las células glómicas y su modulación por dopaminaCanales de calcio de las células glómicas y su modulación por dopamina López Barneo, José; López Barneo, José; Rodríguez Benot, Alberto; Rodríguez Benot, Alberto (1991-07-16) El presente trabajo se centra en el estudio de los canales de Ca2+ de alto umbral y de su modulación metabólica y por ...
Article Single K+ channels in membrane patches of arterial chemoreceptor cells are modulated by 02 tensionSingle K+ channels in membrane patches of arterial chemoreceptor cells are modulated by 02 tension Ganfornina, María Dolores; Ganfornina, María Dolores; López Barneo, José; López Barneo, José (1991-01-01) Type I cells of the carotid body are known to participate in the detection of 02 tension in arterial blood but the primary ...
Article Sodium and Calcium Currents in Dispersed Mammalian Septal NeuronsSodium and Calcium Currents in Dispersed Mammalian Septal Neurons López Barneo, José; López Barneo, José; Castellano Orozco, Antonio Gonzalo; Castellano Orozco, Antonio Gonzalo (1991-01-01) Voltage-gated Na+ and Ca2+ conductances of freshly dissociated septal neurons were studied in the whole-cell configuration ...
PhD Thesis Efecto de la estimulación eléctrica periférica sobre la evolución del dolor lumbarEfecto de la estimulación eléctrica periférica sobre la evolución del dolor lumbar López Barneo, José; López Barneo, José; Escribano Zafra, Antonio; Escribano Zafra, Antonio (1990-06-29) El presente trabajo trata sobre la evolución del dolor lumbar al ser tratado con estimulación eléctrica periférica ...
Article Thyrotropin-releasing-hormone (TRH) and its physiological metabolite TRH-OH inhibit Na+ channel activity in mammalian septal neuronsThyrotropin-releasing-hormone (TRH) and its physiological metabolite TRH-OH inhibit Na+ channel activity in mammalian septal neurons López Barneo, José; López Barneo, José; Castellano Orozco, Antonio Gonzalo; Castellano Orozco, Antonio Gonzalo; Toledo Aral, Juan José; Toledo Aral, Juan José (1990-01-01) The interaction of thyrotropin-releasing hormone (TRH) and its physiological metabolite TRH-OH with Na+ channels was studied ...
PhD Thesis Canales iónicos de neuronas septales aisladas: Caracterización electrofisiológica y modulación por TRH y LHRHCanales iónicos de neuronas septales aisladas: Caracterización electrofisiológica y modulación por TRH y LHRH López Barneo, José; López Barneo, José; Castellano Orozco, Antonio Gonzalo; Castellano Orozco, Antonio Gonzalo (1989-10-02) El presente trabajo continua con una de las líneas de investigación de nuestro grupo que trata del estudio de las propiedades ...
PhD Thesis Adaptación morfofuncional renal tras nefrectomía unilateral en el adultoAdaptación morfofuncional renal tras nefrectomía unilateral en el adulto López Barneo, José; López Barneo, José; Torrubia Romero, Francisco Javier; Torrubia Romero, Francisco Javier (1989-01-30) En el presente estudio se analizaron los cambios morfológicos y funcionales del riñón remanente tras la nefrectomía de ...
Article Properties of Calcium and Potassium Currents of Clonal Adrenocortical CellsProperties of Calcium and Potassium Currents of Clonal Adrenocortical Cells López Barneo, José; López Barneo, José; Tabares, Lucía; Tabares, Lucía; Ureña López, Juan; Ureña López, Juan (1989-01-01) The ionic currents of clonal Y-1 adrenocortical cells were studied using the whole-cell variant of the patch-clamp technique. ...
Article Ionic currents in dispersed chemoreceptor cells of the mammalian carotid bodyIonic currents in dispersed chemoreceptor cells of the mammalian carotid body Ureña López, Juan; Ureña López, Juan; López López, J.; López López, J.; González Montelongo, M. Carmen; González Montelongo, M. Carmen; López Barneo, José; López Barneo, José (1989-01-01) Ionic currents of enzymatically dispersed type I and type II cells of the carotid body have been studied using the whole ...
Article Low pO2 selectively inhibits K channel activity in chemoreceptor cells of the mammalian carotid bodyLow pO2 selectively inhibits K channel activity in chemoreceptor cells of the mammalian carotid body López López, J.; López López, J.; González Montelongo, M. Carmen; González Montelongo, M. Carmen; Ureña López, Juan; Ureña López, Juan; López Barneo, José; López Barneo, José (1989-01-01) The hypothesis that changes in environmental O2 tension (pO2) could affect the ionic conductances of dissociated type I ...
PhD Thesis Repercusión de las alteraciones en la función respiratoria sobre el síndrome de apnea del sueñoRepercusión de las alteraciones en la función respiratoria sobre el síndrome de apnea del sueño López Barneo, José; López Barneo, José; Rodríguez Becerra, Eulogio; Rodríguez Becerra, Eulogio; Castillo Gómez, José; Castillo Gómez, José; León Jiménez, Antonio; León Jiménez, Antonio (1988-10-04) El síndrome de apnea del sueño (SAS), provoca episodios de desaturación nocturna que a la larga provoca hipertensión ...
PhD Thesis Complicaciones pielo-ureterales en el homotransplante renal heterotrópicoComplicaciones pielo-ureterales en el homotransplante renal heterotrópico López Barneo, José; López Barneo, José; Mármol Navarro, Salvador; Mármol Navarro, Salvador (1988-01-01)
PhD Thesis Sistema para la adquisición, almacenamiento y análisis de corrientes iónicas transmembranaSistema para la adquisición, almacenamiento y análisis de corrientes iónicas transmembrana López Barneo, José; López Barneo, José; Mateos Pérez, Juan Carlos; Mateos Pérez, Juan Carlos; Ureña López, Juan; Ureña López, Juan (1987-07-04) El objetivo general del presente trabajo ha sido el diseño e implementación de un sistema automatizado para el control del ...
PhD Thesis Electrofisiología de células adrenocorticales: Estudio mediante el registro intracelular y la técnica de “patch clamp”Electrofisiología de células adrenocorticales: Estudio mediante el registro intracelular y la técnica de “patch clamp” López Barneo, José; López Barneo, José; Tabares, Lucía; Tabares, Lucía (1985-12-16) El presente trabajo se centra en el estudio de las características electrofisiológicas de células adrenocorticales en ...
Article Depolarizing response of rat parathyroid cells to divalent cationsDepolarizing response of rat parathyroid cells to divalent cations López Barneo, José; López Barneo, José; Armstrong, Clay M.; Armstrong, Clay M. (1983-01-01) Membrane potentials were recorded from rat parathyroid glands continuously perfused in vitro. At 1 .5 mM external Ca", the ...
Article Currents recorded through small areas of squid axon membrane with an internal virtual ground voltage clampCurrents recorded through small areas of squid axon membrane with an internal virtual ground voltage clamp López Barneo, José; López Barneo, José; Matteson, Donald R.; Matteson, Donald R.; Armstrong, Clay M.; Armstrong, Clay M. (1981-01-01) A new voltage-clamp apparatus for the squid axon has been implemented to enable recording of currents through small areas ...
PhD Thesis Movimientos oculares y actividad unitaria del cerebelo y del tronco del encéfalo en animales despiertos: Tesis presentada para optar al grado de doctor por la Facultad de Medicina de SevillaMovimientos oculares y actividad unitaria del cerebelo y del tronco del encéfalo en animales despiertos: Tesis presentada para optar al grado de doctor por la Facultad de Medicina de Sevilla Mir Jordano, Diego; Mir Jordano, Diego; López Barneo, José; López Barneo, José (1977-01-01)

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