Artículos (Instituto de Biomedicina de Sevilla (IBIS))
Recent Submissions
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Prenatal Management and Outcome of Junctional Ectopic Tachycardia and Hydrops [Article]
(Arquivos Brasileiros de Cardiologia, 2012-04-09)Fetal dysrhythmias are reported in approximately 1-2% of all pregnancies and are a relatively common reason for referral ...
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Prenatal management and perinatal outcome in giant placental chorioangioma complicated with hydrops fetalis, fetal anemia and maternal mirror syndrome [Article]
(BioMed Central, 2012-07-28)Background: Giant placental chorioangiomas have been associated with a number of severe fetal complications and high ...
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A map of human microRNA variation uncovers unexpectedly high levels of variability [Article]
(BMC, 2012-08-24)Background: MicroRNAs (miRNAs) are key components of the gene regulatory network in many species. During the past few ...
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Trabectedin plus radiotherapy for advanced soft-tissue sarcoma: experience in forty patients treated at a sarcoma reference center [Article]
(MDPI, 2020-12-12)Symptomatic control and tumoral shrinkage is an unmet need in advanced soft-tissue sarcoma (STS) patients beyond first-line. ...
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Primary and acquired resistance to immunotherapy in lung cancer: unveiling the mechanisms underlying of immune checkpoint blockade therapy [Article]
(MDPI, 2020-12-11)After several decades without maintained responses or long-term survival of patients with lung cancer, novel therapies ...
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Integrating Comorbidities and Phenotype-Based Medicine in Patient-Centered Medicine in COPD [Article]
(doi:10.3390/jcm9092745, 2020-08-25)Despite recent notable innovations in the management of chronic obstructive pulmonary disease (COPD), no major advances ...
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Influencers on thyroid cancer onset: molecular genetic basis [Article]
(2019-11-08)Thyroid cancer, a cancerous tumor or growth located within the thyroid gland, is the most common endocrine cancer. It is ...
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Combined use of the Ab105-2фΔCI lytic mutant phage and different antibiotics in clinical isolates of multiresistant Acinetobacter baumannii [Article]
(2019)Phage therapy is an abandoned antimicrobial therapy that has been resumed in recent years. In this study, we mutated ...
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Assessing Autophagy in Archived Tissue or How to Capture Autophagic Flux from a Tissue Snapshot [Article]
(MDPI, 2020)Autophagy is a highly conserved degradation mechanism that is essential for maintaining cellular homeostasis. In human ...
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Breakthrough Technologies Reshape the Ewing Sarcoma Molecular Landscape [Article]
(MDPI, 2020)Ewing sarcoma is a highly aggressive round cell mesenchymal neoplasm, most often occurring in children and young adults. ...
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Metallo-Liposomes of Ruthenium Used as Promising Vectors of Genetic Material [Article]
(MDPI, 2020)Gene therapy is a therapeutic process consisting of the transport of genetic material into cells. The design and preparation ...
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RING1B contributes to Ewing sarcoma development by repressing the Na(V)1.6 sodium channel and the NF-kappa B pathway, independently of the fusion oncoprotein [Article]
(Impact Journals, 2016-06-15)Ewing sarcoma (ES) is an aggressive tumor defined by EWSR1 gene fusions that behave as an oncogene. Here we demonstrate ...
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Multidrug resistance transporter profile reveals MDR3 as a marker for stratification of blastemal Wilms tumour patients [Article]
(Impact Journals, 2017)Wilms tumour (WT) is the most common renal tumour in children. Most WT patients respond to chemotherapy, but subsets of ...
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Neural crest derived progenitor cells contribute to tumor stroma and aggressiveness in stage 4/M neuroblastoma [Article]
(Impact Journals, 2017)Pediatric tumors arise upon oncogenic transformation of stem/progenitor cells during embryonic development. Given this ...
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Single nucleotide polymorphisms as prognostic and predictive biomarkers in renal cell carcinoma. [Article]
(Impact Journals, 2017)Despite major advances in the knowledge of the molecular basis of renal cell carcinoma, prognosis is still defined using ...
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Nestin(+) cells direct inflammatory cell migration in atherosclerosis [Article]
(Nature Research, 2016)Atherosclerosis is a leading death cause. Endothelial and smooth muscle cells participate in atherogenesis, but it is ...
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Dnmt3b knock-down in enteric precursors reveals a possible mechanism by which this de novo methyltransferase is involved in the enteric nervous system development and the onset of Hirschsprung disease [Article]
(Impact Journals, 2017)Hirschsprung disease (HSCR, OMIM 142623) is a pathology that shows a lack of enteric ganglia along of the distal ...
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NLRP3-inflammasome inhibition prevents high fat and high sugar diets-induced heart damage through autophagy induction [Article]
(Impact Journals, 2017)The NLRP3-inflammasome complex has emerged as an important component of inflammatory processes in metabolic dysfunction ...
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Role of VHL, HIF1A and SDH on the expression of miR-210: Implications for tumoral pseudo-hypoxic fate [Article]
(Impact Journals, 2016)The hypoxia-inducible factor 1a (HIF-1a) and its microRNA target, miR-210, are candidate tumor-drivers of metabolic ...
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HMGA2 overexpression predicts relapse susceptibility of blastemal Wilms tumor patients [Article]
(Impact Journals, 2017)Wilms tumor (WT) is an embryonal malignant neoplasm of the kidney that accounts for 6–7% of all childhood cancers. WT ...