Listar Artículos (Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER)) por título
Mostrando ítems 105-124 de 179
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Nuclear Envelope Integrity in Health and Disease: Consequences on Genome Instability and Inflammation
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)The dynamic nature of the nuclear envelope (NE) is often underestimated. The NE protects, regulates, and organizes the ...
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Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair
(Oxford University Press, 2018)The DNA damage response (DDR) is an extensive signaling network that is robustly mobilized by DNA double-strand breaks ...
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Nucleus-translocated mitochondrial cytochrome c liberates nucleophosmin-sequestered ARF tumor suppressor by changing nucleolar liquid-liquid phase separation.
(Nature Research, 2022-10-11)The regular functioning of the nucleolus and nucleus-mitochondria crosstalk are considered unrelated processes, yet ...
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Oestrogen receptor β mediates the actions of bisphenol-A on ion channel expression in mouse pancreatic beta cells
(Springer Nature, 2019-09)Aims/hypothesis: Bisphenol-A (BPA) is a widespread endocrine-disrupting chemical that has been associated with type 2 ...
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Oncogenic p95HER2/611CTF primes human breast epithelial cells for metabolic stress-induced down-regulation of FLIP and activation of TRAIL-R/Caspase-8-dependent apoptosis
(Impact Journals, 2017)Oncogenic transformation triggers reprogramming of cell metabolism, as part of the tumorigenic process. However, metabolic ...
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PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus
(Springer Nature, 2016)[Aims/hypothesis]: A strategy to enhance pancreatic islet functional beta cell mass (BCM) while restraining inflammation, ...
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PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks
(Oxford University Press, 2020)Post-translational histone modifications and chromatin remodelling play a critical role controlling the integrity of the ...
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Physical Forces and Transient Nuclear Envelope Rupture During Metastasis: The Key for Success?
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)During metastasis, invading tumor cells and circulating tumor cells (CTC) face multiple mechanical challenges during ...
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Physical interactions between specifically regulated subpopulations of the MCM and RNR complexes prevent genetic instability
(Public Library of Science, 2024-05-22)The helicase MCM and the ribonucleotide reductase RNR are the complexes that provide the substrates (ssDNA templates and ...
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Population Genetic Structure of the Grasshopper Eyprepocnemis plorans in the South and East of the Iberian Peninsula
(Public Library of Science, 2013)The grasshopper Eyprepocnemis plorans subsp. plorans harbors a very widespread polymorphism for supernumerary (B) chromosomes ...
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Potential use of adipose tissue stem cells in the control of aging
(Federation of Anti-Aging Medicine Societies, 2012)Cell therapy with adult stem cells is a new battle front for the control of aging. Before being used for this purpose, we ...
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Prevalence of dens invaginatus assessed by cbct: systematic review and meta-analysis
(Medicina Oral S.L, 2022)Background: Dens invaginatus is a developmental dental anomaly resulting from an invagination of dental tissues folding ...
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Prevalence of root canal treatments among diabetic patients: systematic review and meta-analysis
(Mdpi, 2023)(1) Apical periodontitis (AP) is the inflammatory response of the periapical tissue to bacterial antigens and toxins ...
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Programming Skeletal Muscle Metabolic Flexibility in Offspring of Male Rats in Response to Maternal Consumption of Slow Digesting Carbohydrates during Pregnancy
(MDPI, 2020)Skeletal muscle plays a relevant role in metabolic flexibility and fuel usage and the associated muscle metabolic inflexibility ...
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PS Integrins and Laminins: Key Regulators of Cell Migration during Drosophila Embryogenesis
(Public Library of Science, 2011)During embryonic development, there are numerous cases where organ or tissue formation depends upon the migration of ...
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PTTG2 silencing results in induction of epithelial-to-mesenchymal transition and apoptosis
(Nature Publishing Group, 2013)Human securin, also known as human pituitary tumor-transforming gene 1 (pttg1), plays a key role in cell-cycle regulation. ...
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R Loops: From Physiologicalto Pathological Roles
(Elsevier, 2019-10-17)DNA-RNA hybrids play a physiological role in cellular processes, but often, they represent non-scheduled co-transcriptional ...
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Rat1p maintains RNA polymerase II CTD phosphorylation balance
(Cold Spring Harbor Laboratory Press, 2014)In S. cerevisiae, the 5′-3′ exonuclease Rat1p partakes in transcription termination. Although Rat1p-mediated RNA degradation ...
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Regulation of replication fork advance and stability by nucleosome assembly
(Multidisciplinary Digital Publishing Institute (MDPI), 2017)he advance of replication forks to duplicate chromosomes in dividing cells requires the disassembly of nucleosomes ahead ...