Browsing Artículos (Fisiología Médica y Biofísica) by Title
Now showing items 311-330 of 332
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Theranostics in boron neutron capture therapy
(MDPI, 2021-04-10)Boron neutron capture therapy (BNCT) has the potential to specifically destroy tumor cells without damaging the tissues ...
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Thyrotropin-releasing-hormone (TRH) and its physiological metabolite TRH-OH inhibit Na+ channel activity in mammalian septal neurons
(1990)The interaction of thyrotropin-releasing hormone (TRH) and its physiological metabolite TRH-OH with Na+ channels was studied ...
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Toward a New Paradigm in Resistance Training by Means of Velocity Monitoring: A Critical and Challenging Narrative
(Springer, 2022-09-16)For more than a century, many concepts and several theories and principles pertaining to the goals, organization, methodology ...
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Transcriptomic analysis reveals an association of FCGBP with Parkinson’s disease
(Nature Research, 2022-11-12)Transcriptomics in Parkinson’s disease (PD) offers new insights into the molecular mechanism of PD pathogenesis. Several ...
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Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders
(Nature Portfolio, 2020)Neurodevelopmental disorders have a heritable component and are associated with region specific alterations in brain ...
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Transcriptomic and connectomic correlates of differential spatial patterning among gliomas
(Oxford University Press, 2022-10-18)Unravelling the complex events driving grade-specific spatial distribution of brain tumour occurrence requires rich datasets ...
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Transgenic NADH dehydrogenase restores oxygen regulation of breathing in mitochondrial complex I-deficient mice
(NATURE PUBLISHING GROUP, 2023)The hypoxic ventilatory response (HVR) is a life-saving reflex, triggered by the activation of chemoreceptor glomus cells ...
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Trasplante de células naturales "dopaminotróficas" nuevo concepto terapeútico antiparkinsoniano
(Viguera, 2003)Aim and method. Parkinson's disease is caused by the degeneration of dopamineric neurons of substantia nigra projecting ...
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Treatment with trkC agonist antibodies delays disease progression in neuromuscular degeneration (nmd) mice
(OXFORD UNIV PRESS, 2005)Spinal muscular atrophy with respiratory distress type 1 (SMARD1) is a fatal autosomal recessive disorder seen in infants. ...
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Trophic restoration of the nigrostriatal dopaminergic pathway in long-term carotid body-grafted parkinsonian rats
(2003)We studied the mechanisms underlying long-term functional recovery of hemiparkinsonian rats grafted intrastriatally with ...
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TRPC and TRPV Channels’ Role in Vascular Remodeling and Disease
(doi:10.3390/ijms21176125, 2020-08-25)Transient receptor potentials (TRPs) are non-selective cation channels that are widely expressed in vascular beds. They ...
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TRPC Channels in the SOCE Scenario
(MDPI, 2020)Transient receptor potential (TRP) proteins form non-selective Ca2+ permeable channels that contribute to the modulation ...
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TRPC6 channels are required for proliferation, migration and invasion of breast cancer cell lines by modulation of Orai1 and Orai3 surface exposure
(MDPI AC, 2018-09-14)Transient receptor potential channels convey signaling information from a number of stimuli to a wide variety of cellular ...
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Two for the Price of One: A Neuroprotective Chaperone Kit within NAD Synthase Protein NMNAT2
(Public Library of Science, 2016-07-25)One of the most fascinating properties of the brain is the ability to function smoothly across decades of a lifespan. ...
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Unexpected obesity, rather than tumorigenesis, in a conditional mouse model of mitochondrial complex II deficiency
(Federation amer soc exp biol, 2021)Mutations in any of the genes encoding the four subunits of succinate dehydrogenase (SDH), a mitochondrial membrane-bound ...
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Upregulation of CD38 expression on multiple myeloma cells by novel HDAC6 inhibitors is a class effect and augments the efficacy of daratumumab
(Nature Publishing Group, 2021)Multiple myeloma (MM) is incurable, so there is a significant unmet need for effective therapy for patients with relapsed ...
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Urocortin Role in Ischemia Cardioprotection and the Adverse Cardiac Remodeling
(MDPI, 2021-11-09)Despite the considerable progress in strategies of myocardial protection, ischemic heart diseases (IHD) and consequent ...
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Urocortin-1 Mediated Cardioprotection Involves XIAP and CD40-Ligand Recovery Role of EPAC2 and ERK12
(Public Library of Science, 2016)Urocortin-1 (Ucn-1) is an endogenous peptide that protects heart from ischemia and reperfusion (I/R) injuries. Ucn-1 is ...
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Urocortin-2 Prevents Dysregulation of Ca2+ Homeostasis and Improves Early Cardiac Remodeling After Ischemia and Reperfusion
(Frontiers Research Foundation, 2018-07-03)Aims: Urocortin-2 (Ucn-2) is a potent cardioprotector against Ischemia and Reperfusion (I/R) injuries. However, little is ...
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Using redox-sensitive fluorescent probes to record real-time reactive oxygen species production in cells from mouse carotid body slices
(Cell Press, 2021)Reactive oxygen species (ROS) are important signaling molecules for physiologic processes such as acute response to ...