Listar Artículos (Fisiología Médica y Biofísica) por título
Mostrando ítems 120-139 de 345
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Fast motor axon loss in SMARD1 does not correspond to morphological and functional alterations of the NMJ
(Elsevier, 2013-06)Spinal muscular atrophy with respiratory distress type 1 (SMARD1) is a childhood motoneuron disease caused by mutations ...
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First aid kit for hypoxic survival: sensors and strategies
(University of Chicago Press, 2010)Survival success under conditions of acute oxygen deprivation depends on efficiency of the central and peripheral ...
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Full protection from SARS-CoV-2 brain infection and damage in susceptible transgenic mice conferred by MVA-CoV2-S vaccine candidate
(Nature Publishing Group, 2023)Vaccines against SARS-CoV-2 have been shown to be safe and effective but their protective efficacy against infection in ...
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Functional and transcriptional induction of Aquaporin-1 gene by hypoxia; analysis of promoter and role of Hif-1α
(2011)Aquaporin-1 (AQP1) is a water channel that is highly expressed in tissues with rapid O2 transport. It has been reported ...
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Functional regeneration of the murine neuromuscular synapse relies on long‑lasting morphological adaptations
(BMC, 2022)Background: In a broad variety of species, muscle contraction is controlled at the neuromuscular junction (NMJ), the ...
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Functional Specificity of the Members of the Sos Family of Ras-GEF Activators: Novel Role of Sos2 in Control of Epidermal Stem Cell Homeostasis
(MDPI, 2021-04-29)Prior reports showed the critical requirement of Sos1 for epithelial carcinogenesis, but the specific functionalities of ...
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Furin prodomain ppfurin enhances ca2+ entry through orai and trpc6 channels’ activation in breast cancer cells
(MDPI, 2021-04-01)Furin, a proprotein convertase that belongs to a family of Ca2+-dependent serine peptidases, is involved in the maturation ...
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Galacto-conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity
(Wiley Open Access, 2020)Pharmacologically active compounds with preferential cytotoxic activity for senescent cells, known as senolytics, can ...
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Gating of O2-sensitive K + Channels of Arterial Chemoreceptor Cells and Kinetic Modifications Induced by Low PO2
(1992)We have studied the kinetic properties of the O2-sensitive K+ channels (KO2 channels) of dissociated glomus cells from ...
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Gene expression analyses reveal metabolic specifications in acute O-2-sensing chemoreceptor cells
(Wiley, 2017-09)Acute O2sensing is a fundamental property of cells in the peripheral chemoreceptors,e.g. glomus cells in the carotid body ...
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Gene expression profiling supports the neural crest origin of adult rodent carotid body stem cells and identifies CD10 as a marker for mesectoderm-committed progenitors
(WILEY, 2016)Neural stem cells (NSCs) are promising tools for understanding nervous system plasticity and repair, but their use is ...
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Generation of human organs in pigs via interspecies blastocyst complementation
(Wiley-Blackwell Verlag GmbH, 2016-10-19)More than eighteen years have passed since the first derivation of human embryonic stem cells (ESCs), but their clinical ...
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Generation of Periventricular Reactive Astrocytes Overexpressing Aquaporin 4 Is Stimulated by Mesenchymal Stem Cell Therapy
(MDPI AG, 2023-03-15)Aquaporin-4 (AQP4) plays a crucial role in brain water circulation and is considered a therapeutic target in hydrocephalus. ...
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Genetic divergence and demography of pudu deer (Pudu puda) in five provinces of southern Chile, analyzed through latitudinal and longitudinal ranges
(Pensoft Publishers, 2022)Pudu deer (Pudu puda) is endemic to the temperate rainforests of Chile. Genetic studies at different geographic scales for ...
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Genetic, cellular, and connectomic characterization of the brain regions commonly plagued by glioma
(Oxford University Press, 2020)For decades, it has been known that gliomas follow a non-random spatial distribution, appearing more often in some brain ...
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Global Evolution of Pathogenic Bacteria With Extensive Use of Fluoroquinolone Agents
(Frontiers Media, 2020)It is well-established that the spread of many multidrug-resistant (MDR) bacteria is predominantly clonal. Interestingly ...
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Glucose sensing by carotid body glomus cells: potential implications in disease
(Frontiers Media, 2014-10-15)The carotid body (CB) is a key chemoreceptor organ in which glomus cells sense changes in blood O2, CO2, and pH levels. ...
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Grey and white matter microstructure is associated with polygenic risk for schizophrenia
(Nature Publishing Group, 2021-08-30)Recent discovery of approximately 270 common genetic variants associated with schizophrenia has enabled polygenic risk ...
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Hepatocellular carcinoma risk-stratification based on ASGR1 in circulating epithelial cells for cancer interception
(Frontiers, 2022-11-28)Purpose: Lack of diagnostic and prognostic biomarkers in hepatocellular carcinoma impedes stratifying patients based on ...
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Heterotopic ossification in mice overexpressing Bmp2 in Tie2+ lineages
(NATURE PUBLISHING GROUP, 2021-07-22)Bone morphogenetic protein (Bmp) signaling is critical for organismal development and homeostasis. To elucidate Bmp2 ...