Browsing Artículos (Fisiología Médica y Biofísica) by Title
Now showing items 260-279 of 332
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Article
Selective accumulation of biotin in arterial chemoreceptors: requirement for carotid body exocytotic dopamine secretion
(2016-12)Biotin is a water-soluble vitamin required for the function of carboxylases as well asfor the regulation of gene expression. ...
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Article
Selective expression of the neurexin substrate for presenilin in the adult forebrain causes deficits in associative memory and presynaptic plasticity
(Elsevier, 2021-10-15)Presenilins (PS) form the active subunit of the gamma-secretase complex, which mediates the proteolytic clearance of a ...
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Article
Selective Glial Cell Line-Derived Neurotrophic Factor Production in Adult Dopaminergic Carotid Body Cells In Situ and after Intrastriatal Transplantation
(2005)Glial cell line-derived neurotrophic factor (GDNF) exerts a notable protective effect on dopaminergic neurons in rodent ...
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Article
Serum protein halogenation and nitrosylation: trait of maintained overstimulation of blood phagocytes in sporadic Parkinson’s disease
(2013)Introduction: Halogenative and nitrosative stress are two types of oxidative stress that have been proposed as pathogenic ...
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Article
Sexually divergent development of depression-related brain networks during healthy human adolescence.
(American Association for the Advancement of Science, 2022)Sexual differences in human brain development could be relevant to sex differences in the incidence of depres- sion during ...
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Article
Simulación en cirugía cardíaca: ¿el futuro de la docencia en nuestra especialidad?
(Sociedad Española de Cirugía Cardiovascular y Endovascular (SECCE), 2017-04-05)Introducción: La simulación como herramienta docente se está estableciendo como una prioridad en los currículos de nuestra ...
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Article
Simvastatin and metformin inhibit cell growth in hepatitis C virus infected cells via mTOR increasing PTEN and autophagy
(2018-01-31)Hepatitis C virus (HCV) infection has been related to increased risk of development of hepa tocellular carcinoma (HCC) ...
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Article
Single K+ channels in membrane patches of arterial chemoreceptor cells are modulated by 02 tension
(1991)Type I cells of the carotid body are known to participate in the detection of 02 tension in arterial blood but the primary ...
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Presentation
Single restraint stress sensitizes acute chewing movements induced by haloperidol, but not if the 5-HT agonist 8-OH-DPAT is given prior to stress
(Elsevier, 1997)The objective of this study was two-fold: ( i) to analyze behavioral sensitization to haloperidol 2 weeks after single ...
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Article
El sistema endógeno de serotonina no participa en la abstinencia opiácea, aunque su inhibición por estimulación del receptor 5-HT1A incrementa la eficacia antidisfórica de la clonidina en ratas
(2003)El objetivo del estudio fue discernir el papel del sistema endógeno de serotonina en la abstinencia opiácea, tanto en su ...
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Article
SMN Is Physiologically Downregulated at Wild-Type Motor Nerve Terminals but Aggregates Together with Neurofilaments in SMA Mouse Models
(MDPI, 2022-10-20)muscular atrophy (SMA). SMN forms the core of a protein complex localized at the cytoplasm and nuclear gems and that ...
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Article
SMN Requirement for Synaptic Vesicle, Active Zone and Microtubule Postnatal Organization in Motor Nerve Terminals
(2011-10-12)Low levels of the Survival Motor Neuron (SMN) protein produce Spinal Muscular Atrophy (SMA), a severe monogenetic disease ...
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Article
Smn-Deficiency Increases the Intrinsic Excitability of Motoneurons
(2017-09-05)During development, motoneurons experience significant changes in their size and in the number and strength of connections ...
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Article
Sodium and Calcium Currents in Dispersed Mammalian Septal Neurons
(1991)Voltage-gated Na+ and Ca2+ conductances of freshly dissociated septal neurons were studied in the whole-cell configuration ...
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Article
SOS GEFs in health and disease
(Elsevier, 2020)SOS1 and SOS2 are the most universal and widely expressed family of guanine exchange factors (GEFs) capable or activating ...
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Article
SOS2 Comes to the Fore: Differential Functionalities in Physiology and Pathology
(MDPI, 2021-06-21)The SOS family of Ras-GEFs encompasses two highly homologous and widely expressed members, SOS1 and SOS2. Despite their ...
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Article
Spanish Cell Therapy Network (TerCel): 15 years of successful collaborative translational research
(Elsevier, 2020)In the current article we summarize the 15-year experience of the Spanish Cell Therapy Network (TerCel), a successful ...
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Article
Spike protein of SARS-CoV-2 Omicron variant An in-silico study evaluating spike interactions and immune evasion
(Frontiers Media, 2022-11-29)Background: The fundamentals of the infectivity and immune evasion of the SARS-CoV-2 Omicron variant are not yet fully ...
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Article
SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells
(Nature Portfolio, 2020)Glioblastoma cancer-stem like cells (GSCs) display marked resistance to ionizing radiation (IR), a standard of care for ...
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Article
State-Dependent Subnetworks of Parvalbumin-Expressing Interneurons in Neocortex
(Cell Press, 2019-02-26)Brain state determines patterns of spiking output that underlie behavior. In neocortex, brain state is reflected in the ...