Perfil del autor: Muñiz Guinea, Manuel
Datos institucionales
| Nombre | Muñiz Guinea, Manuel |
| Departamento | Biología Celular |
| Área de conocimiento | Biología Celular |
| Categoría profesional | Catedrático de Universidad |
| Correo electrónico | Solicitar |
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Estadísticas
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Nº publicaciones
33
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Nº visitas
5838
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Nº descargas
10532
| Publicaciones |
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Artículo
 GPI anchors: Regulated as needed
(Rockefeller University Press, 2023)
GPI anchoring is an essential post-translational modification in eukaryotes that links proteins to the plasma membrane. ... |
Artículo
The P4-ATPase Drs2 Interacts with and Stabilizes the Multisubunit Tethering Complex TRAPPIII in Yeast
(John Wiley & Sons, 2023)
Multisubunit Tethering Complexes (MTCs) are a set of conserved protein complexes that tether vesicles at the acceptor ... |
Artículo
Impact of Sphingolipids on Protein Membrane Trafficking
(Elsevier, 2023)
Membrane trafficking is essential to maintain the spatiotemporal control of protein and lipid distribution within membrane ... |
Tesis Doctoral
Control de calidad de la exportación selectiva del retículo endoplásmico mediada por lípidos
(2022)
El transporte selectivo de proteínas a lo largo de la ruta secretora (sorting) es un proceso esencial para mantener la ... |
Artículo
 The ceramide synthase subunit lac1 regulates cell growth and size in fission yeast
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Cell division produces two viable cells of a defined size. Thus, all cells require mechanisms to measure growth and trigger ... |
Artículo
Crosslinking assay to study a specific cargo-coat interaction through a transmembrane receptor in the secretory pathway
(Public Library of Science, 2022)
Intracellular trafficking through the secretory organelles depends on transient interactions between cargo proteins and ... |
Artículo
CD4+ and CD8+ T-cell responses in bone marrow to fatty acids in high-fat diets
(Elsevier, 2022)
Obesity is associated with disruptions in the adaptive immune system; however, dietary fatty acids in high-fat diets (HFDs) ... |
Artículo
Quality-controlled ceramide-based GPI-anchored protein sorting into selective ER exit sites
(Elsevier, 2022)
Glycosylphosphatidylinositol-anchored proteins (GPI-APs) exit the endoplasmic reticulum (ER) through a specialized export ... |
Tesis Doctoral
Role of Lipids in Protein Sorting From the Endoplasmic Reticulum
(2021)
Protein sorting in the secretory pathway is crucial to maintain cellular compartmentalization and homeostasis. In addition ... |
Artículo
Determination of the lipid composition of the GPI anchor
(PLOS, 2021)
In eukaryotic cells, a subset of cell surface proteins is attached by the glycolipid glycosylphosphatidylinositol (GPI) ... |
Artículo
A Role for Lipids in Protein Sorting?
(Swiss Chemical Society, 2021)
Lipid and protein diversity provides structural and functional identity to the membrane compartments that define the ... |
Artículo
Structural analysis of the GPI glycan
(PLOS, 2021)
Glycosylphosphatidylinositol (GPI) anchoring of proteins is an essential post-translational modification in all eukaryotes ... |
Artículo
The p24 Complex Contributes to Specify Arf1 for COPI Coat Selection
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Golgi trafficking depends on the small GTPase Arf1 which, upon activation, drives the assembly of different coats onto ... |
Artículo
Ceramide chain length–dependent protein sorting into selective endoplasmic reticulum exit sites
(American Association for the Advancement of Science, 2020)
Protein sorting in the secretory pathway is crucial to maintain cellular compartmentalization and homeostasis. In addition ... |
Artículo
Dual Independent Roles of the p24 Complex in Selectivity of Secretory Cargo Export from the Endoplasmic Reticulum
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)
The cellular mechanisms that ensure the selectivity and fidelity of secretory cargo protein transport from the endoplasmic ... |
Artículo
Endoplasmic Reticulum Export of GPI-Anchored Proteins
(MDPI, 2019)
Protein export from the endoplasmic reticulum (ER) is an essential process in all eukaryotes driven by the cytosolic coat ... |
Tesis Doctoral
Papel de los receptores de carga en la organización funcional de la ruta secretora temprana
(2016)
Introducción La organización estructural y funcional de la célula eucariota depende, en gran medida, de la actividad de ... |
Artículo
Trafficking of glycosylphosphatidylinositol anchored proteins from the endoplasmic reticulum to the cell surface
(Elsevier, 2016)
In eukaryotes, many cell surface proteins are attached to the plasma membrane via a glycolipid glycosylphosphatidylinositol ... |
Artículo
Limited ER quality control for GPI-anchored proteins
(Rockefeller University Press, 2016)
Endoplasmic reticulum (ER) quality control mechanisms target terminally misfolded proteins for ER-associated degradation ... |
| Tesis Doctoral |
Artículo
Manganese Redistribution by Calcium-stimulated Vesicle Trafficking Bypasses the Need for P-type ATPase Function
(American Society for Biochemistry and Molecular Biology, 2015)
Regulation of intracellular ion homeostasis is essential for eukaryotic cell physiology. An example is provided by loss ... |
Artículo
Osh proteins regulate COPII-mediated vesicular transport of ceramide from the endoplasmic reticulum in budding yeast
(Company of Biologists Ltd, 2014)
Lipids synthesized at the endoplasmic reticulum (ER) are delivered to the Golgi by vesicular and non-vesicular pathways. ... |
Tesis Doctoral
Análisis funcional de mecanismos de selección molecular que operan en la ruta secretora temprana
(2013)
Introducción La organización estructural y funcional de la célula eucariota depende, en gran medida, de la actividad de ... |
Artículo
Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells
(Elsevier, 2012)
Sphingolipids are not only important components of membranes but also have functions in protein trafficking and intracellular ... |
Artículo
The yeast p24 complex regulates gpi-anchored protein Transport and quality control by monitoring anchor remodeling
(American Society for Cell Biology, 2011)
Glycosylphosphatidylinositol (GPI)-anchored proteins are secretory proteins that are attached to the cell surface of ... |
Tesis Doctoral
Análisis funcional del complejo p24 en Saccharomyces cerevisiae
(2010)
El propósito general de esta tesis es el análisis molecular de la función del complejo p24 en los procesos selectivos de ... |
Artículo
The yeast p24 complex is required for the formation of COPI retrograde transport vesicles from the Golgi apparatus
(Rockefeller University Press, 2008)
The p24 family members are transmembrane proteins assembled into heteromeric complexes that continuously cycle between the ... |
Artículo
The retrieval function of the KDEL receptor requires PKA phosphorylation of its C-terminus
(American Society for Cell Biology, 2003)
The KDEL receptor is a Golgi/intermediate compartment-located integral membrane protein that carries out the retrieval of ... |
Artículo
The Emp24 complex recruits a specific cargo molecule into endoplasmic reticulum-derived vesicles
(Rockefeller University Press, 2000)
Members of the yeast p24 family, including Emp24p and Erv25p, form a heteromeric complex re- quired for the efficient ... |
Artículo
Protein kinase A activity is required for the budding of constitutive transport vesicles from the trans-Golgi network
(National Academy of Sciences of the USA, 1997)
We have examined the role played by protein kinase A (PKA) in vesicle-mediated protein transport from the trans-Golgi ... |
Tesis Doctoral
Regulación de la estructura y función del complejo de Golgi por factores citosólicos y proteínas G heterotriméricas
(1996)
Las células eucariotas están organizadas en una serie de compartimentos delimitados por membranas lipídicas. En cada ... |
Artículo
A Regulatory Role for cAMP-dependent Protein Kinase in Protein Traffic along the Exocytic Route
(The American Society for Biochemistry and Molecular Biology, 1996)
The influence of protein kinase A activity on transport of newly synthesized vesicular stomatitis virus G glycoprotein along ... |
Artículo
Trimeric G proteins regulate the cytosol-induced redistribution of Golgi enzymes into the endoplasmic reticulum
(Company of Biologists Ltd, 1995)
Streptolysin O-permeabilized cells incubated with a high concentration (5-10 mg/ml) of cytosolic proteins and ATPgenerating system ... |