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New Castanospermine Glycoside Analogues Inhibit Breast Cancer Cell Proliferation and Induce Apoptosis without Affecting Normal Cells

 

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Opened Access New Castanospermine Glycoside Analogues Inhibit Breast Cancer Cell Proliferation and Induce Apoptosis without Affecting Normal Cells
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Author: Allan, Ghada
Ouadid-Ahidouch, Halima
Sánchez Fernández, Elena Matilde
Risquez Cuadrado, Rocío
García Fernández, José Manuel
Ortiz Mellet, Carmen
Ahidouch, Ahmed
Department: Universidad de Sevilla. Departamento de Química orgánica
Date: 2013
Published in: Plos One, 8 (10), e76411-.
Document type: Article
Abstract: sp2-Iminosugar-type castanospermine analogues have been shown to exhibit anti-tumor activity. However, their effects on cell proliferation and apoptosis and the molecular mechanism at play are not fully understood. Here, we investigated the effect o...
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Cite: Allan, G., Ouadid-Ahidouch, H., Sánchez Fernández, E.M., Risquez Cuadrado, R., García Fernández, J.M., Ortiz Mellet, C. y Ahidouch, A. (2013). New Castanospermine Glycoside Analogues Inhibit Breast Cancer Cell Proliferation and Induce Apoptosis without Affecting Normal Cells. Plos One, 8 (10), e76411-.
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Format: PDF

URI: http://hdl.handle.net/11441/57348

DOI: http://dx.doi.org/10.1371/journal.pone.0076411

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