Perfil del autor: Sánchez Fernández, Elena Matilde
Datos institucionales
Nombre | Sánchez Fernández, Elena Matilde |
Departamento | Química Orgánica |
Área de conocimiento | Química Orgánica |
Categoría profesional | Profesora Titular de Universidad |
Correo electrónico | Solicitar |
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Estadísticas
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Nº publicaciones
21
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Nº visitas
2290
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Nº descargas
2554
Publicaciones |
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Artículo
![]() Speeding-up the Determination of Protein-Ligand Affinities by STD NMR: The Reduced Data Set STD NMR Approach (rd-STD NMR)
(American Chemical Society, 2024)
STD NMR spectroscopy is a powerful ligand-observed NMR tool for screening and characterizing the interactions of small ... |
Artículo
![]() A selenoureido-iminoglycolipid transported by zeolitic-imidazolate framework nanoparticles: a novel antioxidant therapeutic approach
(Royal Society of Chemistry, 2023)
A selenium-containing metal–organic framework with remarkable antioxidant capacity and ROS-scavenging activity was constructed ... |
Artículo
![]() Fluoro-labelled sp2-iminoglycolipids with immunomodulatory properties
(Elsevier, 2023)
The unique electronic properties of the fluorine atom make its strategic incorporation into a bioactive compound a very ... |
Capítulo de Libro
![]() La implicación del alumnado como fuerza motriz en el desarrollo de la asignatura Experimentación en Química II
(Universidad de Sevilla, 2023)
El ciclo de mejora aplicado en la asignatura Experimentación en Química II del Grado en Ingeniería Química Industrial ... |
Capítulo de Libro
![]() Exploración de la combinación de diferentes herramientas didácticas sobre el aprendizaje activo del alumnado
(Universidad de Sevilla, 2023)
El Ciclo de Mejora en el Aula planteado para el curso académico 2022-2023 se ha llevado a cabo en la asignatura obligatoria ... |
Artículo
![]() Unravelling the Inflammatory Processes in the Early Stages of Diabetic Nephropathy and the Potential Effect of (Ss)-DS-ONJ
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Inflammatory processes play a central role in the pathogenesis of diabetic nephropathy (DN) in the early stages of the ... |
Artículo
![]() Synthesis of sp2-Iminosugar Selenoglycolipids as Multitarget Drug Candidates with Antiproliferative, Leishmanicidal and Anti-Inflammatory Properties
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
sp2-Iminosugar glycolipids (sp2-IGLs) represent a consolidated family of glycoconjugate mimetics encompassing a ... |
Artículo
![]() Anti-Inflammatory (M2) Response Is Induced by a sp2-Iminosugar Glycolipid Sulfoxide in Diabetic Retinopathy
(Frontiers, 2021)
Diabetic retinopathy (DR) is one of the most common complications of Diabetes Mellitus (DM) and is directly associated ... |
Artículo
![]() Stereoselective Synthesis of Iminosugar 2-Deoxy(thio)glycosides from Bicyclic Iminoglycal Carbamates Promoted by Cerium(IV) Ammonium Nitrate and Cooperative Brønsted Acid-Type Organocatalysis
(American Chemical Society, 2020)
The first examples of iminosugar-type 2-deoxy(thio)glycoside mimetics are reported. The key step is the activation of a ... |
Artículo
![]() Synthesis, conformational analysis and: In vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment
(Royal Society of Chemistry, 2020)
The Tn antigen (GalNAc-α-1-O-Thr/Ser) is a well-known tumor-associated carbohydrate determinant. The use of glycopeptides ... |
Artículo
![]() sp2-Iminosugar Glycolipids as Inhibitors of Lipopolysaccharide-mediated Human Dendritic Cell Activation in Vitro and of Acute Inflammation in Mice in Vivo
(Elsevier, 2019)
Glycolipid mimetics consisting of a bicyclic polyhydroxypiperidine-cyclic carbamate core and a pseudoanomeric hydrophobic ... |
Artículo
![]() Thiol-ene "Click" Synthesis and Pharmacological Evaluation of C-Glycoside sp2-Iminosugar Glycolipids
(MDPI, 2019)
The unique stereoelectronic properties of sp2-iminosugars enable their participation in glycosylation reactions, thereby ... |
Artículo
![]() Nuevas estrategias en el proceso de enseñanza-aprendizaje de la asignatura Experimentación Química II del Grado en Ingeniería Química Industrial
(Universidad de Sevilla, 2018)
El trabajo realizado durante el desarrollo del ciclo de mejora experimentado en la asignatura Experimentación en Química ... |
Artículo
![]() Fluorinated chaperone-ß-cyclodextrin formulations for ß-glucocerebrosidase activity enhancement in neuronopathic Gaucher disease
(American Chemical Society, 2017)
Amphiphilic glycomimetics encompassing a rigid, undistortable nor-tropane skeleton based on 1,6-anhydro-L-idonojirimycin ... |
Tesis Doctoral |
Artículo
![]() Conformationally-Locked C-Glycosides: Tuning Aglycone Interactions for Optimal Cheperone Behaviour in Gaucher Fibroblasts
(Royal Society of Chemistry, 2016)
A series of conformationally locked C-glycosides based on the 3-aminopyrano[3,2-b]pyrrol-2(1H)-one (APP) scaffold has been ... |
Artículo
![]() Glycomimetic-based pharmacological chaperones for lysosomal storage disorders: lessons from Gaucher, GM1-gangliosidosis and Fabry diseases
(Royal Society of Chemistry, 2016)
Lysosomal storage disorders (LSDs) are often caused by mutations that destabilize native folding and impair the trafficking ... |
Trabajo Fin de Máster
![]() Iminoazúcares sp2 en inmunoterapias contra el cáncer
(2016)
En la actualidad, los tratamientos más utilizados para combatir el cáncer se basan en el uso de quimioterapia, radioterapia ... |
Artículo
![]() Antileishmanial activity of sp2-iminosugar derivatives
(Royal Society of Chemistry, 2015)
A series of sp2-iminosugar-type glycomimetics bearing S-linked pseudoglycoside substituents (sulfide, sulfoxide and sulfone ... |
Artículo
![]() New Castanospermine Glycoside Analogues Inhibit Breast Cancer Cell Proliferation and Induce Apoptosis without Affecting Normal Cells
(Public Library of Science, 2013)
sp2-Iminosugar-type castanospermine analogues have been shown to exhibit anti-tumor activity. However, their effects on ... |
Patente
![]() Derivados sp2, imnoazúcar como inhibidores de las alfa-glicosidasas.
(Oficina Española de Patentes y Marcas , 2011)
Derivados sp2 imnoazúcar como inhibidores de las ?-glicosidasas.Derivados glicosilados de fórmula I, donde los significados ... |