Listar Artículos (Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER)) por título
Mostrando ítems 42-61 de 181
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Editorial: Molecular chaperones and neurodegeneration
(Frontiers Media, 2017) -
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EGF-induced adipose tissue mesothelial cells undergo functional vascular smooth muscle differentiation
(Nature Publishing Group, 2014)Recent studies suggested that the post-natal mesothelium retain differentiative potential of the embryonic mesothelium, ...
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Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability
(Elsevier, 2019)Although correlations between RNA polymerase II (RNAPII) transcription stress, R-loops, and genome instability have been ...
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Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency
(Springer Nature, 2020)The ATM kinase is a master regulator of the DNA damage response to double-strand breaks (DSBs) and a well-established ...
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Enzyme-Responsive Zr-Based Metal-Organic Frameworks for Controlled Drug Delivery: Taking Advantage of Clickable PEG-Phosphate Ligands
(American Chemical Society, 2023)We report for the first time the controlled drug release from a nanoscale Zr-based metal-organic framework (MOF), UiO-66, ...
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Epigenetic features of human telomeres
(Oxford University Press, 2018)Although subtelomeric regions in humans are heterochromatic, the epigenetic nature of human telomeres remains controversial. ...
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EXO1 and DNA2-mediated ssDNA gap expansion is essential for ATR activation and to maintain viability in BRCA1-deficient cells
(Oxford University Press, 2024-06-24)DNA replication faces challenges from DNA lesions originated from endogenous or exogenous sources of stress, leading to ...
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Expression of human RECQL5 in Saccharomyces cerevisiae causes transcription defects and transcription-associated genome instability
(Springer Nature, 2024-05-26)RECQL5 is a member of the conserved RecQ family of DNA helicases involved in the maintenance of genome stability that is ...
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Expression of TDRD9 in a subset of lung carcinomas by CpG island hypomethylation protects from DNA damage
(Impact Journals, 2018)Tudor domain containing protein 9 (TDRD9) is a RNA helicase normally expressed in the germline, where it is involved in ...
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FANCD2 facilitates replication through common fragile sites
(Elsevier, 2016)Common fragile sites (CFSs) are genomic regions that are unstable under conditions of replicative stress. Although the ...
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FANCD2 maintains replication fork stability during misincorporation of the DNA demethylation products 5-hydroxymethyl-2’-deoxycytidine and 5-hydroxymethyl-2’-deoxyuridine
(Springer Nature, 2022)Fanconi anemia (FA) is a rare hereditary disorder caused by mutations in any one of the FANC genes. FA cells are mainly ...
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Gene gating at nuclear pores prevents the formation of R loops
(Taylor and Francis Ltd., 2018)Transcription is an important source of genetic variability. A large amount of transcription-associated genome variation ...
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Gene-Diet Interactions in Type 2 Diabetes: The Chicken and Egg Debate
(MDPI, 2017)Consistent evidence from both experimental and human studies indicates that Type 2 diabetes mellitus (T2DM) is a complex ...
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Generation of a human iPS cell line from a patient with retinitis pigmentosa due to EYS mutation
(Elsevier, 2018-11-16)Retinitis pigmentosa (RP) is an inherited retinal degenerative disease. Mutations in EYS have been associated with autosomal ...
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Generation of a Vero-Based Packaging Cell Line to Produce SV40 Gene Delivery Vectors for Use in Clinical Gene Therapy Studies
(Elsevier, 2017)Replication-defective (RD) recombinant simian virus 40 (SV40)-based gene delivery vectors hold a great potential for ...
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Glutamine, MTOR and autophagy: a multiconnection relationship
(Taylor & Francis, 2022)Cancer cells metabolize glutamine mostly through glutaminolysis, a metabolic pathway that activates MTORC1. The AMPK-MTORC1 ...
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Golgi localisation of GMAP210 requires two distinct cis-membrane binding mechanisms
(BMC, 2009)Background The Golgi apparatus in mammals appears as a ribbon made up of interconnected stacks of flattened cisternae ...
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Guidelines and recommendations on yeast cell death nomenclature
(Shared Science Publishers, 2018)Elucidating the biology of yeast in its full complexity has major implications for science, medicine and industry. One of ...
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Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways
(Shared Science Publishers OG, 2019)Understanding the plasticity of genomes has been greatly aided by assays for recombination, repair and mutagenesis. These ...
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Harmful DNA:RNA hybrids are formed in cis and in a Rad51-independent manner
(eLife Sciences Publications, 2020)DNA:RNA hybrids constitute a well-known source of recombinogenic DNA damage. The current literature is in agreement with ...