Article
The Emerging Role of RNA Modifications in DNA Double-Strand Break Repair
Author/s | Jimeno González, Sonia
Romero Balestra, Fernando Huertas Sánchez, Pablo |
Department | Universidad de Sevilla. Departamento de Genética |
Publication Date | 2021 |
Deposit Date | 2021-06-04 |
Published in |
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Abstract | The correct repair of DNA double-strand breaks is essential for maintaining the stability of the genome, thus ensuring the survival and fitness of any living organism. Indeed, the repair of these lesions is a complicated ... The correct repair of DNA double-strand breaks is essential for maintaining the stability of the genome, thus ensuring the survival and fitness of any living organism. Indeed, the repair of these lesions is a complicated affair, in which several pathways compete for the DNA ends in a complex balance. Thus, the fine-tuning of the DNA double-strand break repair pathway choice relies on the different regulatory layers that respond to environmental cues. Among those different tiers of regulation, RNA modifications have just emerged as a promising field. © Copyright |
Funding agencies | Agencia Estatal de Investigación. España 10.13039/50110001103 |
Project ID. | PID2019-104195G
10.13039/50110001103 |
Citation | Jimeno González, S., Romero Balestra, F. y Huertas Sánchez, P. (2021). The Emerging Role of RNA Modifications in DNA Double-Strand Break Repair. Frontiers in Molecular Biosciences, 8, 664872. |
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