Perfil del autor: Jimeno González, Sonia
Datos institucionales
Nombre | Jimeno González, Sonia |
Departamento | Genética |
Área de conocimiento | Genética |
Categoría profesional | Profesora Titular de Universidad |
Correo electrónico | Solicitar |
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Estadísticas
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Nº publicaciones
19
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Nº visitas
3998
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Nº descargas
3195
Publicaciones |
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Tesis Doctoral
![]() Molecular basis of Aicardi-Goutières syndrome
(2023)
DNA is an essential molecule for the proper functioning of the cell that is constantly exposed to exogenous and endogenous ... |
Tesis Doctoral
![]() Non-canonical DNA structures in Double Strand Break repair
(2023)
DNA double-strand breaks (DSBs) pose a serious threat to genome stability, so their proper repair is crucial for cell ... |
Artículo
![]() N7-methylguanosine methylation of tRNAs regulates survival to stress in cancer
(Springer Nature, 2023)
Tumour progression and therapy tolerance are highly regulated and complex processes largely dependent on the plasticity ... |
Artículo
![]() ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair
(Nature Publishing Group, 2021)
The maintenance of genomic stability requires the coordination of multiple cellular tasks upon the appearance of DNA ... |
Artículo
![]() The effect of atypical nucleic acids structures in DNA double strand break repair: a tale of R-loops and G-quadruplexes
(Frontiers Media S.A., 2021)
The fine tuning of the DNA double strand break repair pathway choice relies on different regulatory layers that respond ... |
Artículo
![]() The Emerging Role of RNA Modifications in DNA Double-Strand Break Repair
(Frontiers Media S.A., 2021)
The correct repair of DNA double-strand breaks is essential for maintaining the stability of the genome, thus ensuring the ... |
Artículo
![]() EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks
(Nature Research, 2019)
The exosome is a ribonucleolytic complex that plays important roles in RNA metabolism. Here we show that the exosome is ... |
Artículo
![]() The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures
(Elsevier, 2018)
DNA breaks are complex lesions that can be repaired either by non-homologous end joining (NHEJ) or by homologous recombination ... |
Artículo
![]() A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination
(Public Library of Science, 2017)
Replication forks stall at different DNA obstacles such as those originated by transcription. Fork stalling can lead to ... |
Tesis Doctoral
![]() Regulación de la reparación de los cortes de doble cadena en el ADN: papel de la nedilación de proteínas
(2016)
Las roturas de doble cadena del ADN son las lesiones más citotóxicas que pueden ocurrir en el ADN. Pueden ser reparadas ... |
Artículo
![]() Neddylation inhibits CtIP-mediated resection and regulates DNA double strand break repair pathway choice
(Oxford University Press, 2015)
DNA double strand breaks are the most cytotoxic lesions that can occur on the DNA. They can be repaired by different ... |
Artículo
![]() Histone H3K56 Acetylation, Rad52, and Non-DNA Repair Factors Control Double-Strand Break Repair Choice with the Sister Chromatid
(Public Library of Science, 2013)
DNA double-strand breaks (DSBs) are harmful lesions that arise mainly during replication. The choice of the sister chromatid ... |
Artículo |
Artículo
![]() New suppressors of THO mutations identify Thp3 (Ypr045c)-Csn12 as a protein complex involved in transcription elongation
(American Society for Microbiology, 2011)
Formation of a ribonucleoprotein particle (mRNP) competent for export requires the coupling of transcription with mRNA ... |
Artículo
![]() CtIP Mutations Cause Seckel and Jawad Syndromes
(Public Library of Science, 2011)
Seckel syndrome is a recessively inherited dwarfism disorder characterized by microcephaly and a unique head profile. ... |
Artículo
![]() The THO complex as a key mRNP biogenesis factor in development and cell differentiation
(BioMed Central, 2010)
The THO complex is a key component in the co-transcriptional formation of messenger ribonucleoparticles that are competent ... |
Artículo
![]() Sem1 is a functional component of the nuclear pore complex–associated messenger RNA export machinery
(Rockefeller University Press, 2009)
The evolutionarily conserved protein Sem1/Dss1 is a subunit of the regulatory particle (RP) of the proteasome, and, in ... |
Artículo
![]() Tho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutants
(American Society for Microbiology, 2006)
THO is a protein complex that functions in cotranscriptional mRNP formation. Yeast THO1 and SUB2 (Saccharomyces cerevisiae) ... |
Artículo
![]() Molecular evidence that the eukaryotic THO/TREX complex is required for efficient transcription elongation
(American Society for Biochemistry and Molecular Biology Inc., 2003)
THO/TREX is a conserved eukaryotic complex formed by the core THO complex plus proteins involved in mRNA metabolism and ... |