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Artículo
miR-7 Modulates hESC Differentiation into Insulin-Producing Beta-like Cells and Contributes to Cell Maturation
(The American Society of Gene and Cell Therapy, 2018-09-07)
Human pluripotent stem cells retain the extraordinary capacity to differentiate into pancreatic beta cells. For this particular lineage, more effort is still required to stress the importance of developing an efficient, ...
Artículo
Human Mesenchymal Stem Cells Prevent Neurological Complications of Radiotherapy
(Frontiers Media S.A., 2019-05-16)
Radiotherapy is a highly effective tool for the treatment of brain cancer. However, radiation also causes detrimental effects in the healthy tissue, leading to neurocognitive sequelae that compromise the quality of life ...
Artículo
Impact of transient down-regulation of DREAM in human embryonic stem cell pluripotency: The role of DREAM in the maintenance of hESCs
(Elsevier, 2016)
Little is knownabout the functions of downstreamregulatory element antagonist modulator (DREAM) inembryonic stem cells (ESCs). However, DREAM interacts with cAMP response element-binding protein (CREB) in a Ca2+-dependent ...
Artículo
Therapeutic Potential of Mesenchymal Stem Cells for Cancer Therapy
(Frontiers Media S.A., 2020)
Mesenchymal stem cells (MSCs) are among the most frequently used cell type for regenerative medicine. A large number of studies have shown the beneficial effects of MSC-based therapies to treat different pathologies, ...