Artículos (Fisiología Médica y Biofísica)
Envíos recientes
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Feedback modulation of orai1alpha and orai1beta protein content mediated by STIM proteins
(Wiley, 2024)Store-operated Ca^2+ entry is a mechanism controlled by the filling state of the intracellular Ca^2+ stores, predominantly ...
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Molecular and micro-architectural mapping of gray matter alterations in psychosis
(Springer Nature, 2024-09-12)The psychosis spectrum encompasses a heterogeneous range of clinical conditions associated with abnormal brain development. ...
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Mecanismos patogénicos en la fibrosis pulmonar idiopática. Implicación de los canales de Aquoporina 1
(Asociación de Neumólogos del Sur, 2019)La fibrosis pulmonar idiopática (FPI) es una enfermedad pulmonar intersticial difusa (EPID) y progresiva. La FPI resulta ...
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Aquaporin-1 plays important role in proliferation by affecting cell cycle progression
(Wiley, 2016-06-16)Aquaporin-1 (AQP1) has been associated with tumor development. Here, we investigated how AQP1 may affect cell proliferation. ...
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Rearrangement of cell types in the rat carotid body neurogenic niche induced by chronic intermittent hypoxia
(Wiley, 2023-01-17)The carotid body (CB) is a prototypical acute oxygen (O2)-sensing organ that mediates reflex hyperventilation and increased ...
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Carotid body function in tyrosine hydroxylase conditional Olfr78 knockout mice
(Oxford University Press, 2024-02-22)The Olfr78 gene encodes a G-protein-coupled olfactory receptor that is expressed in several ectopic sites. Olfr78 is one ...
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Presenilin/γ-Secretase Regulates Neurexin Processing at Synapses
(Public Library of Science, 2011-04-29)Neurexins are a large family of neuronal plasma membrane proteins, which function as trans-synaptic receptors during ...
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Dual-promoter lentiviral vectors for constitutive and regulated gene expression in neurons
(Elsevier, 2008-02-15)Gene transfer methods for efficient co-expression of exogenous proteins in neurons are crucial tools towards the understanding ...
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Rare variants analysis of neurexin-1β in autism reveals a novel start codon mutation affecting protein levels at synapses
(Lippincott, Williams & Wilkins, 2013-08-07)Neurexins are synaptic plasma membrane proteins encoded by three genes (NRXN1, -2, -3) with alternative promoters. Mutations ...
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A truncating mutation in Alzheimer's disease inactivates neuroligin-1 synaptic function
(Elsevier, 2015-09-03)Neuroligins (NLs) are cell-adhesion proteins that regulate synapse formation and function. Neuroligin 1 (NL1) promotes the ...
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Molecular and Cellular Mechanisms of Synaptopathies
(Wiley Open Access, 2017-04-30)Synapses, contact points between neurons, are essential elements supporting the ability of neurons to communicate and to ...
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Proteolytic Processing of Neurexins by Presenilins Sustains Synaptic Vesicle Release
(Society for Neuroscience, 2018-01-24)Proteolytic processing of synaptic adhesion components can accommodate the function of synapses to activity-dependent ...
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A Neuroligin-1 mutation associated with Alzheimer’s disease produces memory and age-dependent impairments in hippocampal plasticity
(Cell Press, 2023-05-13)Alzheimer’s disease (AD) is characterized by memory impairments and age-dependent synapse loss. Experimental and clinical ...
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Microglia mitochondrial complex I deficiency during development induces glial dysfunction and early lethality
(Nature, 2024-07-24)Primary mitochondrial diseases (PMDs) are associated with pediatric neurological disorders and are traditionally related ...
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The Complex Role of Store Operated Calcium Entry Pathways and Related Proteins in the Function of Cardiac, Skeletal and Vascular Smooth Muscle Cells
(Frontiers Media, 2018-03-21)Cardiac, skeletal, and smooth muscle cells shared the common feature of contraction in response to different stimuli. ...
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Valor pronóstico de la bioimpedancia eléctrica medida con el dispositivo IVOL en la insuficiencia cardiaca aguda
(Elsevier, 2024)Introducción y objetivos: La evaluación actual de la insuficiencia cardiaca (IC) aguda no permite predecir adecuadamente ...
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Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells
(2016-08-07)Systemic treatments for hepatocellular carcinoma (HCC) have been largely unsuccessful. This study investigated the ...
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An Indocyanine Green-Based Nanoprobe for In Vivo Detection of Cellular Senescence
(Wiley, 2024)Abstract: There is an urgent need to improve conventional cancer-treatments by preventing detrimental side effects, cancer ...
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Redox signaling in acute oxygen sensing
(Elsevier, 2017-04-26)Acute oxygen (O2) sensing is essential for individuals to survive under hypoxic conditions. The carotid body (CB) is the ...
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NLRP3-inflammasome inhibition prevents high fat and high sugar diets-induced heart damage through autophagy induction
(Impact Journals LLC, 2017-09-08)The NLRP3-inflammasome complex has emerged as an important component of inflammatory processes in metabolic dysfunction ...