Browsing Artículos (Fisiología Médica y Biofísica) by Title
Now showing items 216-235 of 332
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Oxygen sensing by ion channels and chemotransduction in single glomus cells
(1996)We have monitored cytosolic [Ca2+] and dopamine release in intact fura-2-loaded glomus cells with microfluoroimetry and a ...
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Oxygen-sensitive calcium channels in vascular smooth muscle and their possible role in hypoxic arterial relaxation
(1995)We have investigated the modifications of cytosolic [Ca2+] and the activity of Ca2+ channels in freshly dispersed arterial ...
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Parkinson’s disease patient-specific neuronal networks carrying the LRRK2 G2019S mutation unveil early functional alterations that predate neurodegeneration
(Springer Nature, 2021)A deeper understanding of early disease mechanisms occurring in Parkinson’s disease (PD) is needed to reveal restorative ...
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Peripheral Organ Equivalent Dose Estimation Procedure in Proton Therapy
(Frontiers Research Foundation, 2022)The aim of this work is to present a reproducible methodology for the evaluation of total equivalent doses in organs ...
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Physiological Plasticity of Neural-Crest-Derived Stem Cells in the Adult Mammalian Carotid Body
(Cell Press, 2017)Adult stem cell plasticity, or the ability of somatic stem cells to cross boundaries and differentiate into unrelated ...
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PKCα-Mediated Downregulation of RhoA Activity in Depolarized Vascular Smooth Muscle: Synergistic Vasorelaxant Effect of PKCα and ROCK Inhibition
(2019-02-18)Background/Aims: Protein kinase C (PKC)- and RhoA/Rho-associated kinase (ROCK) play important roles in arterial sustained ...
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La plasticidad sináptica mediada por endocannabinoides y «trastornos por consumo de drogas»
(Elsevier, 2019)Las drogas impactan en los circuitos de recompensa cerebrales y originan depen dencia y adicción, lo que se define actualmente ...
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Platelet-activating Factor Receptor Initiates Contact of Acinetobacter baumannii Expressing Phosphorylcholine with Host Cells
(2012-06)Adhesion is an initial and important step in Acinetobacter baumannii causing infections. However, the exact molecular ...
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Podoplanin Gene Disruption in Mice Promotes in vivo Neural Progenitor Cells Proliferation, Selectively Impairs Dentate Gyrus Synaptic Depression and Induces Anxiety-Like Behaviors.
(2020-01-15)Podoplanin (Pdpn), a brain-tumor-related glycoprotein identified in humans and animals, is endogenously expressed in ...
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Potassium Channel Types in Arterial Chemoreceptor Cells and Their Selective Modulation by Oxygen
(1992)Single K+ channel currents were recorded in excised membrane patches from dispersed chemoreceptor cells of the rabbit ...
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Practical Application of Networks in Neurosurgery: Combined 3-Dimensional Printing, Neuronavigation, and Preoperative Surgical Planning
(Elsevier, 2020)BACKGROUND: A plethora of cutting-edge neuroimaging analyses have been developed and published, yet they have not hitherto ...
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Preclinical [18F]tetrafluoroborate-PET/CT imaging of pituitary gland hyperplasia
(Oxford, 2018)By blocking of sodium–iodide symporter (NIS) in thyroid gland with potassium perchlorate administered in drinking water ...
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Predicted Value of MicroRNAs, Vascular Endothelial Growth Factor, and Intermediate Monocytes in the Left Adverse Ventricular Remodeling in Revascularized ST-Segment Elevation Myocardial Infarction Patients
(Frontiers Media S.A, 2022)Background: Primary percutaneous coronary intervention (PPCI) in patients with ST-segment elevation myocardial infarction ...
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Preferred Sites of Exocytosis and Endocytosis Colocalize during High- But Not Lower-Frequency Stimulation in Mouse Motor Nerve Terminals
(SOC NEUROSCIENCE, 2009)The spatial relationship of exocytosis and endocytosis in motor nerve terminals has been explored, with varied results, ...
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Prenatal treatment with rapamycin restores enhanced hippocampal mGluR‑LTD and mushroom spine size in a Down’s syndrome mouse model
(BioMed Central Ltd, 2021)Down syndrome (DS) is the most frequent genetic cause of intellectual disability including hippocampal-dependent memory ...
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Presenilin/gamma-secretase regulates neurexin processing at synapses
(2011)Neurexins are a large family of neuronal plasma membrane proteins, which function as trans-synaptic receptors during ...
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Presynaptic Mitochondria Communicate With Release Sites for Spatio-Temporal Regulation of Exocytosis at the Motor Nerve Terminal
(Frontiers Research Foundation, 2022)Presynaptic Ca2+ regulation is critical for accurate neurotransmitter release, vesicle reloading of release sites, and ...
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Prolyl Hydroxylase-dependent Modulation of Eukaryotic Elongation Factor 2 Activity and Protein Translation under Acute Hypoxia
(American Society for Biochemistry and Molecular Biology, 2012-02-03)Early adaptive responses to hypoxia are essential for cell survival, but their nature and underlying mechanisms are poorly ...
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Properties of Calcium and Potassium Currents of Clonal Adrenocortical Cells
(1989)The ionic currents of clonal Y-1 adrenocortical cells were studied using the whole-cell variant of the patch-clamp technique. ...
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Protection and repair of the nigrostriatal pathway with stem-cell-derived carotid body glomus cell transplants in chronic MPTP Parkinsonian model
(MDPI, 2023-03-14)Antiparkinsonian carotid body (CB) cell therapy has been proven to be effective in rodent and nonhuman primate models of ...