Farmacología
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New Eunicellin-Type Diterpenes from the Panamanian Octocoral Briareum Asbestinum [Article]
(MDPI, 2020)Gorgonian octocorals are considered a prolific source of secondary metabolites with a wide range of biological activities, including anti-inflammatory activity. In particular, the genus Briareum is known for producing a ...
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Potential Protective Role Exerted by Secoiridoids from Olea europaea L. in Cancer, Cardiovascular, Neurodegenerative, Aging-Related, and Immunoinflammatory Diseases [Article]
(MDPI, 2020)Iridoids, which have beneficial health properties, include a wide group of cyclopentane [c] pyran monoterpenoids present in plants and insects. The cleavage of the cyclopentane ring leads to secoiridoids. Mainly, secoiridoids ...
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Pomace Olive Oil Concentrated in Triterpenic Acids Restores Vascular Function, Glucose Tolerance and Obesity Progression in Mice [Article]
(MDPI, 2020)Pomace olive oil, an olive oil sub-product, is a promising source of bioactive triterpenoids such as oleanolic acid and maslinic acid. Considering the vascular actions of pomace olive oil and the potential effects of the ...
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Virgin Olive Oil and Health: Summary of the III International Conference on Virgin Olive Oil and Health Consensus Report, JAEN (Spain) 2018 [Article]
(MDPI, 2019-09-01)The Mediterranean diet is considered as the foremost dietary regimen and its adoption is associated with the prevention of degenerative diseases and an extended longevity. The preeminent features of the Mediterranean diet ...
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Antioxidant, antitumor, and anti-inflammatory activity of natural products obtained from the brown alga Cystoseira usneoides [PhD Thesis]
(2019-11-26)Macroalgae are an inexhaustible source of natural products that display a variety of pharmacological and biological activities. Among marine algae, the genus Cystoseira has proven to produce a wide variety of secondary ...
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Evaluación económica y análisis de impacto presupuestario de mepolizumab en asma eosinofílica refractaria grave [Article]
(Grupo Aula Médica S.L., 2019)Objetivo: Mepolizumab está indicado como tratamiento adicional del asma eosinofílica refractaria grave. Las diferencias observadas en subgrupos poblacionales según recuento eosinofílico plasmático, existencia de pacientes ...
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Deciphering GRINA/Lifeguard1: Nuclear Location, Ca2+ Homeostasis and Vesicle Transport [Article]
(MDPI, 2019)The Glutamate Receptor Ionotropic NMDA-Associated Protein 1 (GRINA) belongs to the Lifeguard family and is involved in calcium homeostasis, which governs key processes, such as cell survival or the release of neurotransmitters. ...
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Fucoxanthin and Rosmarinic Acid Combination Has Anti-Inflammatory Effects through Regulation of NLRP3 Inflammasome in UVB-Exposed HaCaT Keratinocytes [Article]
(MDPI, 2019)Excessive exposure to ultraviolet (UV) radiation is the main risk factor to develop skin pathologies or cancer because it encourages oxidative condition and skin inflammation. In this sense, strategies for its prevention ...
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Interacciones potenciales entre productos fitoterápicos con laxantes antracénicos y otros fármacos. Detección en farmacias comunitarias de Sevilla [Article]
(Sociedad Española de Farmacia Comunitaria (SEFAC), 2018-12-28)Introducción: Los productos fitoterápicos más dispensados en España son los laxantes. Los laxantes antracénicos como el acíbar de aloe (Aloe spp.) o la corteza de cáscara sagrada (Rhamnus purshianus), entre otros, podrían ...
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Historia y actualidad de productos para la piel, cosméticos y fragancias. Especialmente los derivados de las plantas [Article]
(Facultad de Farmacia de la Universidad de Granada, 2017)Objetivo: aportar notas históricas sobre el empleo de los recursos vegetales en la elaboración de productos para el cuidado de la piel y recoger hechos científicos que nos definen la actualidad del tema. Método: búsqueda ...
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Estudio botánico y farmacéutico de productos con aplicación en cosmética y cuidado de la piel [Article]
(Facultad de Farmacia, Universidad de Granada, 2017)Objetivos: revisar productos comerciales con ingredientes vegetales que se emplean en higiene personal y cosmética de uso diario. Reunir, en forma de catálogo, consideraciones botánicas y farmacéuticas de estos ...
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Characterization of Ferrofluid-Based Stimuli-Responsive Elastomers [Article]
(Frontiers Media, 2016-12)Stimuli-responsive materials undergo physicochemical and/or structural changes when a specific actuation is applied. They are heterogeneous composites, consisting of a non-responsive matrix where functionality is provided ...
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Estrategia de desprescripción en pacientes pluripatológicos. [PhD Thesis]
(2019-02-22)A causa del envejecimiento poblacional, la prevalencia de los pacientes con enfermedades crónicas ha aumentado considerablemente en los últimos años, siendo un colectivo que requiere especial atención aquellos pacientes ...
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Fucoxanthin-Containing Cream Prevents Epidermal Hyperplasia and UVB-Induced Skin Erythema in Mice [Article]
(MDPI, 2018-10-10)Microalgae represent a source of bio-active compounds such as carotenoids with potent anti-inflammatory and antioxidant properties. We aimed to investigate the effects of fucoxanthin (FX) in both in vitro and in vivo skin ...
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Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility [Article]
(American Heart Association, 2015)Background Leukocyte migration is critical for the infiltration of monocytes and accumulation of monocyte derived macrophages in inflammation. Considering that Hck and Fgr are instrumental in this process, their impact ...
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Thymus carnosus boiss [PhD Thesis]
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The Cockayne syndrome protein B is involved in the repair of 5-AZA-2′-deoxycytidine-induced DNA lesions [Article]
(Impact Journals, 2018)The Cockayne Syndrome Protein B (CSB) plays an essential role in Transcription-Coupled Nucleotide Excision Repair (TC-NER) by recruiting repair proteins once transcription is blocked with a DNA lesion. In fact, CSB-deficient ...
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Mecanismos implicados en la gastroprotección mediada por ibuprofeno/L-arginina [PhD Thesis]
(1999-10-22)Sería casi excepcional encontrar hoy en día a un paciente afectado de dolor articular e inflamación que no consuma o haya consumido antiinflamatorios no esteroideos (AINE). Sin embargo, con las dosis habituales de cualquiera ...