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Mostrando ítems 1-10 de 53
Artículo
Lack of biochemical correlation between the protective effect of prostaglandins and nitric oxide pathway on NSAID-induced gastric injury
(Publishing House Zaslavsky, 1998-04)
Artículo
Effects of Oleacein, a New Epinutraceutical Bioproduct from Extra Virgin Olive Oil, in LPS-Activated Murine Immune Cells
(MDPI, 2022)
The present study was designed to evaluate the immunomodulatory effects of the secoiridoid from extra virgin olive oil, oleacein (OLA), deepening into the possible signaling pathways involved in LPS-activated murine ...
Tesis Doctoral
Mecanismos patogénicos de las lesiones gastrointestinales inducidas por meloxicam y piroxicam.
(2001-04-03)
Los antiinflamatorios no esteroides (AINE) se encuentran entre los fármacos más consumidos en todo el mundo. Su amplia utilización está avalada por sus propiedades analgésicas, antiinflamatorias y antipiréticas. Sin embargo, ...
Tesis Doctoral
Consecuencias de la inhibición de la ciclooxigenasa-2 en modelos experimentales de inflamación intestinal: Mecanismos moleculares implicados
(2005-07-14)
El término de EII, se utiliza desde hace años para designar a las enfermedades inflamatorias del intestino, grueso principalmente, de etiología desconocida y de evolución crónica. Si bien las causas de la EII permanecen ...
Artículo
Polyphenolic Extract (PE) from Olive Oil Exerts a Potent Immunomodulatory Effect and Prevents Graft-versus-Host Disease in a Mouse Model
(Elsevier, 2020)
Polyphenols are a group of chemical substances found in plants, with immunomodulatory, antiproliferative, and anti-inflammatory properties that might be useful in the prophylaxis and treatment of graft-versus-host disease ...
Artículo
Potential Protective Role Exerted by Secoiridoids from Olea europaea L. in Cancer, Cardiovascular, Neurodegenerative, Aging-Related, and Immunoinflammatory Diseases
(MDPI, 2020)
Iridoids, which have beneficial health properties, include a wide group of cyclopentane [c] pyran monoterpenoids present in plants and insects. The cleavage of the cyclopentane ring leads to secoiridoids. Mainly, secoiridoids ...
Artículo
(R)-8-Methylsulfinyloctyl isothiocyanate from Nasturtium officinale inhibits LPS-induced immunoinflammatory responses in mouse peritoneal macrophages: chemical synthesis and molecular signaling pathways involved
(Royal Society of Chemistry, 2023-07-20)
The aim of this study was to develop an optimal synthetic route to obtain natural (R)-8-methylsulfinyloctyl isothiocyanate ((R)-8-OITC), present in watercress, based on the “DAG methodology” as well as to evaluate its ...
Artículo
Extra virgin olive oil polyphenolic extracts downregulate inflammatory responses in LPS-activated murine peritoneal macrophages suppressing NFκB and MAPK signalling pathways
(2014)
Extra virgin olive oil (EVOO) is obtained from the fruit of the olive tree Olea europaea L. Phenolic compounds present in EVOO have recognized anti-oxidant and anti-inflammatory properties. However, the activity of the ...
Artículo
Remdesivir and mortality reduction in COVID-19 patients: a systematized subgroup analysis of clinical trials
(Sociedad Española de Farmacia Hospitalaria, 2021)
Objective: Remdesivir has not shown survival benefit for patients with severe COVID-19. However, subgroup analysis of ACTT-1 Study Group showed an apparent reduction in mortality for patients who required non-high-flow ...