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Mostrando ítems 1-10 de 29
Artículo
Effects of Oleacein, a New Epinutraceutical Bioproduct from Extra Virgin Olive Oil, in LPS-Activated Murine Immune Cells
(MDPI, 2022)
The present study was designed to evaluate the immunomodulatory effects of the secoiridoid from extra virgin olive oil, oleacein (OLA), deepening into the possible signaling pathways involved in LPS-activated murine ...
Artículo
Polyphenolic Extract (PE) from Olive Oil Exerts a Potent Immunomodulatory Effect and Prevents Graft-versus-Host Disease in a Mouse Model
(Elsevier, 2020)
Polyphenols are a group of chemical substances found in plants, with immunomodulatory, antiproliferative, and anti-inflammatory properties that might be useful in the prophylaxis and treatment of graft-versus-host disease ...
Artículo
Potential Protective Role Exerted by Secoiridoids from Olea europaea L. in Cancer, Cardiovascular, Neurodegenerative, Aging-Related, and Immunoinflammatory Diseases
(MDPI, 2020)
Iridoids, which have beneficial health properties, include a wide group of cyclopentane [c] pyran monoterpenoids present in plants and insects. The cleavage of the cyclopentane ring leads to secoiridoids. Mainly, secoiridoids ...
Artículo
Extra virgin olive oil polyphenolic extracts downregulate inflammatory responses in LPS-activated murine peritoneal macrophages suppressing NFκB and MAPK signalling pathways
(2014)
Extra virgin olive oil (EVOO) is obtained from the fruit of the olive tree Olea europaea L. Phenolic compounds present in EVOO have recognized anti-oxidant and anti-inflammatory properties. However, the activity of the ...
Artículo
Remdesivir and mortality reduction in COVID-19 patients: a systematized subgroup analysis of clinical trials
(Sociedad Española de Farmacia Hospitalaria, 2021)
Objective: Remdesivir has not shown survival benefit for patients with severe COVID-19. However, subgroup analysis of ACTT-1 Study Group showed an apparent reduction in mortality for patients who required non-high-flow ...
Artículo
Functional Features of the Exopolysaccharide Extracts Produced by Lactiplantibacillus Strains Isolated from Table Olives
(Royal Society of Chemistry, 2024)
This study evaluates the functional characteristics of the exopolysaccharide (EPS) extracts produced by various strains of Lactiplantibacillus pentosus (LPG1, 119, 13B4, and Lp13) and Lactiplantibacillus plantarum (Lp15) ...
Artículo
Extra-virgin olive oil and its phenolic extract prevent inflammatory response and joint damage in murine experimental arthritis
(Instituto de la Grasa, 2016)
he consumption of EVOO in Mediterranean countries has shown beneficial effects. A wide range of evidence indicates that the phenolic compounds present in EVOO are endowed with anti-inflammatory properties. In this work, ...
Artículo
Age-related changes in melatonin synthesis in rat extrapineal tissues
(Elsevier, 2009-05)
In the search of new therapeutic targets improving the quality of life of elderly, melatonin, “the chemical expression of darkness”, seems to play a remarkable role in aging process possibly due to its antioxidant, ...
Tesis Doctoral
Estudio fitoquímico y farmacológico de retama monosperma boissier
(2016-02-10)
La alta diversidad de especies vegetales con importantes propiedades terapéuticas, ha promovido en los últimos años un incremento en las investigaciones científicas, que buscan comprobar los conocimientos de la medicina ...
Artículo
(−)-Methyl-Oleocanthal, a New Oleocanthal Metabolite Reduces LPS-Induced Inflammatory and Oxidative Response: Molecular Signaling Pathways and Histones Epigenetic Modulation
(MDPI, 2022)
The antioxidant and anti-inflammatory responses of (−)-methyl-oleocanthal (met-OLE), a new metabolite of the extra virgin olive oil (EVOO) phenolic oleocanthal (OLE), were explored in lipopolysaccharide (LPS)-induced murine ...