Listar Artículos (Química Orgánica) por título
Mostrando ítems 60-79 de 263
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Cyclodextrin- and calixarene-based polycationic amphiphiles as gene delivery systems: A structure-activity relationship study
(Royal Society of Chemistry, 2015)Multi-head/multi-tail facial amphiphiles built on cyclodextrin (CD) and calixarene (CA) scaffolds are paradigmatic examples ...
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Cyclodextrin-Based Functional Glyconanomaterials
(MDPI, 2020-12)Cyclodextrins (CDs) have long occupied a prominent position in most pharmaceutical laboratories as “off-the-shelve” tools ...
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Cyclodextrin-Based Nanostructure Efficiently Delivers siRNA to Glioblastoma Cells Preferentially via Macropinocytosis
(MDPI, 2020)Small interfering ribonucleic acid (siRNA) has the potential to revolutionize therapeutics since it can knockdown very ...
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Cyclodextrin-mediated Crystallization of Acid β-glucosidase in Complex with Amphiphilic Bicyclic Nojirimycin Analogues
(Royal Society of Chemistry, 2011)Cyclodextrin-based host-guest chemistry has been exploited to facilitate co-crystallization of recombinant human acid ...
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Cyclodextrin-scaffolded amphiphilic aminoglucoside clusters: self-assembling and gene delivery capabilities
(Royal Society of Chemistry, 2014)Precise control over the architecture of gene carriers is instrumental to manipulate gene delivery efficiency. Combining ...
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Cyclopentyl Methyl Ether (CPME): A Versatile Eco-Friendly Solvent for Applications in Biotechnology and Biorefineries
(Wiley, 2019-05)The quest for sustainable solvents is currently a matter of intense research and development, as solvents significantly ...
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Debates: An Useful Tool to Promote Students Deeper Thinking in Stem Disciplines
(MDPI AG, 2018)The utility of debates for the evaluation of a series of transversal competences related to critical thinking is highlighted. ...
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Deep Eutectic Solvents as Catalysts in the Synthesis of Active Pharmaceutical Ingredients and Precursors
(MDPI, 2024-02-02)Deep Eutectic Solvents (DESs) have appeared in recent years as an appealing alternative to classical organic solvents, due ...
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Deracemisation Processes Employing Organocatalysis and Enzyme Catalysis
(Wiley-Blackwell, 2020)Deracemisation methods have demonstrated their importance in the preparation of chiral compounds in the last few years. ...
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Desarrollo de líneas experimentales para su aplicación en los Trabajos de Fin de Grado en Química
(Universitat de València: Centre de Formació i Qualitat "Manuel Sanchis Guarner", 2012)Desde el punto de vista académico, los Trabajos Fin de Grado en Ciencias Químicas se presentan como proyectos experimentales ...
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Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H2O2- and Aβ1-42-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells
(MDPI, 2019)With the lack of available drugs able to prevent the progression of Alzheimer’s disease (AD), the discovery of new ...
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Development of polycationic amphiphilic cyclodextrin nanoparticles for anticancer drug delivery
(2017)Background: Paclitaxel is a potent anticancer drug that is effective against a wide spectrum of cancers. To overcome its ...
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Development of tacrine clusters as positively cooperative systems for the inhibition of acetylcholinesterase
(Taylor & Francis Open Access, 2021)The synthesis of four tetra-tacrine clusters where the tacrine binding units are attached to a central scaffold via linkers ...
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Dialkylaminodifluorosulfinium salts: XtalFluor-E and XtalFluor-M
(Georg Thieme Verlag, 2013)(A) Failure of Hydrocinnamyl Alcohol with XtalFluor-M: The reaction of hydrocinnamyl alcohol with 2 or 1 in acetonitrile ...
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Dietary oleocanthal supplementation prevents inflammation and oxidative stress in collagen-induced arthritis in mice
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)Oleocanthal (OLE), a characteristic and exclusive secoiridoid of Oleoaceae family, is mainly found in extra virgin olive ...
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Discovery of a Potent α ‑ Galactosidase Inhibitor by in Situ Analysis of a Library of Pyrrolizidine − (Thio)urea Hybrid Molecules Generated via Click Chemistry
(American Chemical Society, 2018)The parallel synthesis of a 26-membered-library of aromatic/aliphatic-(thio)urea-linked pyrrolizidines followed by in ...
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Discovery of human hexosaminidase inhibitors by in situ screening of a library of mono- and divalent pyrrolidine iminosugars
(Elsevier, 2022)Two libraries of mono- and dimeric pyrrolidine iminosugars were synthesized by CuAAC and (thio)urea-bond-forming reactions ...
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Divergent approach to nanoscale glycomicelles and photo-responsive supramolecular glycogels. Implications for drug delivery and photoswitching lectin affinity
(Royal Society of Chemistry, 2023-10-09)The field of stimuli-responsive supramolecular biomaterials has rapidly advanced in recent years, with potential applications ...