Perfil del autor: Miguel Rodríguez, Manuel de
Datos institucionales
Nombre | Miguel Rodríguez, Manuel de |
Departamento | Citología e Histología Normal y Patológica |
Área de conocimiento | Histología |
Categoría profesional | Catedrático de Universidad |
Correo electrónico | Solicitar |
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Estadísticas
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Nº publicaciones
40
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Nº visitas
5807
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Nº descargas
12942
Publicaciones |
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Artículo
![]() Effects of polyphenolic maqui ( Aristotelia chilensis ) extract on the inhibition of NLRP3 inflammasome and activation of mast cells in a mouse model of Crohn's disease-like colitis
(Frontiers Media S.A., 2024)
Introduction: Crohn’s disease (CD) involves activation of mast cells (MC) and NFкB in parallel with the PPAR-a/NLRP3 ... |
Artículo
![]() Native Chilean Berries Preservation and In Vitro Studies of a Polyphenol Highly Antioxidant Extract from Maqui as a Potential Agent against Inflammatory Diseases
(MDPI, 2021)
The best conservation method for native Chilean berries has been investigated in combination with an implemented large-scale ... |
Artículo
![]() Quantification of Boron Compound Concentration for BNCT Using Positron Emission Tomography
(MDPI, 2020)
Boron neutron capture therapy requires a 2 mM 10B concentration in the tumor. The well-known BNCT patient treatment method ... |
Artículo
![]() Mitochondrial imbalance as a new approach to the study of fibromyalgia
(Dovepress, 2020)
Background: Fibromyalgia (FM) is a common chronic pain disease, whose pathogenic mechanism still remains elusive. Oxidative ... |
Artículo
![]() ![]() Polyphenolic Maqui Extract as a Potential Nutraceutical to Treat TNBS-Induced Crohn' s Disease by the Regulation of Antioxidant and Anti-Inflammatory Pathways
(MDPI, 2020)
Nutraceuticals include a wide variety of bioactive compounds, such as polyphenols, which have been highlighted for their ... |
Tesis Doctoral
![]() Nuevas terapias bioactivas preventivas y terapéuticas en un modelo animal de enfermedad de Crohn
(2019)
La enfermedad inflamatoria intestinal (EII), como la enfermedad de Crohn (EC) y la colitis ulcerosa (CU), son un trastorno ... |
Tesis Doctoral |
Artículo
![]() Fibroblasts Collagen Production and Histological Alterations in Hereditary Gingival Fibromatosis
(MDPI, 2019)
Hereditary gingival fibromatosis is a disorder for which the etiology remains unknown. We aimed to evaluate the fibroblasts ... |
Artículo
![]() Preclinical [18F]tetrafluoroborate-PET/CT imaging of pituitary gland hyperplasia
(Oxford, 2018)
By blocking of sodium–iodide symporter (NIS) in thyroid gland with potassium perchlorate administered in drinking water ... |
Artículo
![]() Amitriptyline down-regulates coenzyme Q10 biosynthesis in lung cancer cells
(Elsevier, 2017)
Amitriptyline, a tricyclic antidepressant, has been proposed as an antitumoral drug in oxidative therapy. Its ... |
Artículo
![]() Fibromyalgia syndrome and temporomandibular disorders with muscular pain. A review
(2017)
Objectives: Temporomandibular disorders (TMD) refer to a group of clinical picture affecting the masticatory muscles and ... |
Artículo
![]() Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells
(2016)
Systemic treatments for hepatocellular carcinoma (HCC) have been largely unsuccessful. This study investigated the antitumoral ... |
Tesis Doctoral
![]() Influencia de los parámetros mitocondriales en el agradamiento gingival inducido por ciclosporina y nifedipina: ensayo sobre modelo animal
(2016)
El agrandamiento gingival es una entidad patológica englobada dentro de la clasificación de la enfermedad periodontal. Las ... |
Artículo
![]() Targeted multifunctional tannic acid nanoparticles
(The Royal Society of Chemistry, 2016)
Tannic acid (TA) has multiple effects against cancer, being especially promising in those types that overexpress the ... |
Patente. Invención
![]() Modelo de roedor para fibromialgia y dolor crónico
(Oficina Española de Patentes y Marcas (OEPM), 2015)
El objeto de la presente invención se refiere a un modelo de roedor para fibromialgia y dolor crónico, inducido por ... |
Artículo
![]() Coenzyme Q(10) Therapy
(KARGER, 2014)
For a number of years, coenzyme Q 10 (CoQ 10 ) was known for its key role in mitochondrial bioenergetics; later ... |
Trabajo Fin de Máster |
Artículo
![]() Apoptotic microtubules delimit an active caspase free area in the cellular cortex during the execution phase of apoptosis
(NATURE PUBLISHING GROUP, 2013)
Apoptotic microtubule network (AMN) is organized during apoptosis, forming a cortical structure beneath plasma membrane, which ... |
Artículo
![]() Is Inflammation a Mitochondrial Dysfunction-Dependent Event in Fibromyalgia?
(Mary Ann Liebert, Inc., 2013)
Fibromyalgia (FM) is a complex disorder that affects up to 5% of the general population worldwide. Both mitochondrial ... |
Artículo |
Artículo
![]() Melatonin-synthesizing enzymes and melatonin receptor in rat thyroid cells
(Universidad de Murcia. Departamento de Biología Celular e Histología, 2012)
Melatonin is an indoleamine with a wide spectrum of biological activities other than transmitting photoperiod information, ... |
Artículo |
Artículo
![]() Oxidative Stress Correlates with Headache Symptoms in Fibromyalgia: Coenzyme Q10 Effect on Clinical Improvement
(Public Library of Science, 2012)
Background: Fibromyalgia (FM) is a chronic pain syndrome with unknown etiology and a wide spectrum of symptoms such as ... |
Patente. Invención
![]() Uso de amitriptilina como agente antitumoral para el tratamiento de cáncer de pulmón.
(Oficina Española de Patentes y Marcas , 2011)
Uso de amitriptilina como agente antitumoral para el tratamiento de cáncer de pulmón.Composición farmacéutica que comprende ... |
Tesis Doctoral
![]() Estudio etiopatogénico del linfoepitelioma no endémico
(2011)
El carcinoma nasofaríngeo (CNF) es una neoplasia que tiene una alta incidencia en China y algunas áreas del sudeste asiático, ... |
Artículo
![]() Clinical symptoms in fibromyalgia are better associated to lipid peroxidation levels in blood mononuclear cells rather than in plasma
(Public Library of Science, 2011)
Background: We examined lipid peroxidation (LPO) in blood mononuclear cells (BMCs) and plasma, as a marker of oxidative ... |
Artículo
![]() The cadherin–catenin complex in nasopharyngeal carcinoma
(SPRINGER, 2011)
Abnormal Wnt signaling and impaired cell–cell adhesion due to abnormal E-cadherin and b-catenin func tion have been ... |
Artículo
![]() Inmunohistochemical Profile of Solid Cell Nest of Thyroid Gland
(Humana Press Inc., 2011)
It It is widely held that solid cell nests (SCN) of the thyroid are ultimobranchial body remnants. SCNs are composed of ... |
Tesis Doctoral
![]() Estudio molecular del cáncer de tiroides experimental
(2010)
La tiroides es una glándula endocrina de origen ectodérmico que se desarrolla precozmente en la porción cefálica del tubo ... |
Artículo
![]() Acute oxidant damage promoted on cancer cells by amitriptyline in comparison with some common chemotherapeutic drugs
(Wolters Kluwer Health, 2010)
Oxidative therapy is a relatively new anticancer strategy based on the induction of high levels of oxidative stress, achieved ... |
Tesis Doctoral
![]() Aproximación al estudio biomolecular del carcinoma nasofaríngeo
(2010)
El carcinoma nasofaríngeo se presenta con baja incidencia en los países occidentales, siendo muy frecuente en países ... |
Artículo
![]() Mitochondrial dysfunction and mitophagy activation in blood mononuclear cells of fibromyalgia patients: implications in the pathogenesis of the disease
(BioMed Central, 2010)
Introduction: Fibromyalgia is a chronic pain syndrome with unknown etiology. Recent studies have shown some evidence ... |
Artículo
![]() Thyrotropin-releasing hormone receptor expression in thyroid follicular cells: a new paracrine role of C-cells?
(Universidad de Murcia. Departamento de Biología Celular e Histología, 2005)
Thyrotropin-releasing hormone (TRH) synthesized in the hypothalamus has the capability of inducing the release of ... |
Artículo
![]() Contribution of the microvessel network to the clonal and kinetic profiles of adrenal cortical proliferative lesions
(W.B. Saunders Co., 2001)
Monoclonal adrenocortical lesions have been characterized by an inverse correlation between proliferation and apoptosis, ... |
Artículo
![]() Germline RET 634 Mutation Positive MEN 2A-related C-Cell Hyperplasias Have Genetic Features Consistent with Intraepithelial Neoplasia
(The Endocrine Society, 2001)
C-cell hyperplasias are normally multifocal in multiple endocrine neoplasia type 2A. We compared clonality, microsatellite ... |
Artículo
![]() Clonal patterns in phaeochromocytomas and MEN-2A adrenal medullary hyperplasias: histological and kinetic correlates
(John Wiley & Sons, 2000)
The relationship among histological features, cell kinetics, and clonality has not been studied in adrenal medullary ... |
Artículo
![]() cDNA Sequence and Genomic Structure of the Rat Ret Proto-Oncogene
(Informa Healthcare, 2000)
The RET proto-oncogene, a member of the Receptor Tyrosine Kinase family, plays a crucial role during the development of ... |
Artículo
![]() Kinetic profiles of intraepithelial and invasive prostatic neoplasias: the key role of down-regulated apoptosis in tumor progression
(Springer, 2000)
The cell kinetic of prostatic intraepithelial neoplasia (PIN) is poorly understood. Herein we report the kinetic pattern ... |
Artículo
![]() Clonality as Expression of Distinctive Cell Kinetics Patterns in Nodular Hyperplasias and Adenomas of the Adrenal Cortex
(Elsevier Science, 2000)
Although histopathologic criteria for adrenal cortical nodular hyperplasias (ACNHs) and adenomas (ACAs) have been developed, ... |
Tesis Doctoral
![]() Análisis de ADN y cuantificación de la microvascularización en lesiones proliferativas córtico-suprarrenales
(1996)
En varias neoplasias de origen endocrino o neuroendocrino, existe el dilema de la clasificación correcta en cuanto a su ... |