Perfil del autor: Díaz Quintana, Antonio Jesús
Datos institucionales
| Nombre | Díaz Quintana, Antonio Jesús |
| Departamento | Bioquímica Vegetal y Biología Molecular |
| Área de conocimiento | Bioquímica y Biología Molecular |
| Categoría profesional | Profesor Titular de Universidad |
| Correo electrónico | Solicitar |
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Estadísticas
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Nº publicaciones
66
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Nº visitas
7306
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Nº descargas
10956
| Publicaciones |
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Artículo
 Nicotinamide N-methyltransferase (NNMT) regulates the glucocorticoid signaling pathway during the early phase of adipogenesis
(Springer Nature, 2023)
Obesity is associated with adipose tissue dysfunction through the differentiation and expansion of pre-adipocytes to ... |
Artículo
Neddylation of phosphoenolpyruvate carboxykinase 1 controls glucose metabolism
(Elsevier, 2023)
Neddylation is a post-translational mechanism that adds a ubiquitin-like protein, namely neural precursor cell expressed ... |
Artículo
The Histone Chaperones SET/TAF-1β and NPM1 Exhibit Conserved Functionality in Nucleosome Remodeling and Histone Eviction in a Cytochrome c-Dependent Manner
(Wiley-Blackwell, 2023)
Chromatin homeostasis mediates essential processes in eukaryotes, where histone chaperones have emerged as major regulatory ... |
Artículo
Mitochondrial Factors in the Cell Nucleus
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
The origin of eukaryotic organisms involved the integration of mitochondria into the ancestor cell, with a massive gene ... |
Artículo
Nucleus-translocated mitochondrial cytochrome c liberates nucleophosmin-sequestered ARF tumor suppressor by changing nucleolar liquid-liquid phase separation.
(Nature Research, 2022)
The regular functioning of the nucleolus and nucleus-mitochondria crosstalk are considered unrelated processes, yet ... |
Artículo
PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ
(Elsevier, 2022)
Intrinsic protein flexibility is of overwhelming relevance for intermolecular recognition and adaptability of highly dynamic ... |
Artículo
Phosphorylation disrupts long-distance electron transport in cytochrome c
(Springer Nature, 2022)
t has been recently shown that electron transfer between mitochondrial cytochrome c and the cytochrome c1 subunit of the ... |
Artículo
PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ
(Research Network of Computational and Structural Biotechnology, 2022)
Intrinsic protein flexibility is of overwhelming relevance for intermolecular recognition and adaptability of highly dynamic ... |
Artículo
Proposed mechanism for regulation of H2O2-induced programmed cell death in plants by binding of cytochrome c to 14-3-3 proteins
(Wiley-Blackwell, 2021)
Programmed cell death (PCD) is crucial for development and homeostasis of all multicellular organisms. In human cells, the ... |
Artículo
ARL15 modulates magnesium homeostasis through N-glycosylation of CNNMs
(Springer, 2021)
Cyclin M (CNNM1-4) proteins maintain cellular and body magnesium (Mg2+) homeostasis. Using various biochemical approaches, ... |
Artículo
Post-translational Control of RNA-Binding Proteins and Disease-Related Dysregulation
(Frontiers Media S.A., 2021)
Cell signaling mechanisms modulate gene expression in response to internal and external stimuli. Cellular adaptation ... |
Artículo
Inhibition of the PP2A activity by the histone chaperone ANP32B is long-range allosterically regulated by respiratory cytochrome c
(Elsevier, 2021)
Repair of injured DNA relies on nucleosome dismantling by histone chaperones and de-phosphorylation events carried out by ... |
Artículo
Mitochondrial cytochrome c shot towards histone chaperone condensates in the nucleus
(Wiley-Blackwell, 2021)
Despite mitochondria being key for the control of cell homeostasis and fate, their role in DNA damage response is usually ... |
Artículo
Post-Translational Modifications of Cytochrome c in Cell Life and Disease
(MDPI, 2020)
Mitochondria are the powerhouses of the cell, whilst their malfunction is related to several human pathologies, including ... |
Artículo
Exploring protein phosphorylation by combining computational approaches and biochemical methods
(Elsevier, 2020)
Post-translational modifications of proteins expand their functional diversity, regulating the response of cells to a ... |
Artículo
Wheel and Deal in the Mitochondrial Inner Membranes: The Tale of Cytochrome c and Cardiolipin
(Hindawi, 2020)
Cardiolipin oxidation and degradation by different factors under severe cell stress serve as a trigger for genetically ... |
Artículo
Protonation of the Cysteine Axial Ligand Investigated in His/Cys c-Type Cytochrome by UV-Vis and Mid- And Far-IR Spectroscopy
(American Chemical Society, 2020)
His/Cys coordination was recently found in several c-type cytochromes, which could act as sensors, in electron transport ... |
Artículo
Structural insights into the intracellular region of the human magnesium transport mediator CNNM4
(Multidisciplinary Digital Publishing Institute (MDPI), 2019)
The four member family of “Cyclin and Cystathionine β-synthase (CBS) domain divalent metal cation transport mediators”, ... |
Artículo
SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer
(Elsevier, 2019)
BACKGROUND: Even though liver kinase B1 (LKB1) is usually described as a tumor suppressor in a wide variety of tissues, ... |
Artículo
Pantothenate Rescues Iron Accumulation in Pantothenate Kinase-Associated Neurodegeneration Depending on the Type of Mutation
(Springer Nature, 2019)
Neurodegeneration with brain iron accumulation (NBIA) is a group of inherited neurologic disorders in which iron accumulates ... |
Artículo
Cytochrome c: Surfing Off of the Mitochondrial Membrane on the Tops of Complexes III and IV
(Elsevier, 2019)
The proper arrangement of protein components within the respiratory electron transport chain is nowadays a matter of intense ... |
Artículo
Protein crosslinking improves the thermal resistance of plastocyanin immobilized on a modified gold electrode
(Elsevier, 2018)
Increasing the thermal stability of immobilized proteins is a motivating goal for improving the performance of electrochemical ... |
Artículo
Key Role of the Local Hydrophobicity in the East Patch of Plastocyanins on Their Thermal Stability and Redox Properties
(American Chemical Society, 2018)
Understanding the molecular basis of the thermal stability and functionality of redox proteins has important practical ... |
Artículo
Oxidative stress is tightly regulated by cytochrome c phosphorylation and respirasome factors in mitochondria
(National Academy of Sciences, 2018)
Respiratory cytochrome c has been found to be phosphorylated at tyrosine 97 in the postischemic brain upon neuroprotective ... |
Artículo
A putative RNA binding protein from Plasmodium vivax apicoplast
(Wiley, 2018)
Malaria is caused by Apicomplexa protozoans from the Plasmodium genus entering the bloodstream of humans and animals through ... |
Artículo
Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition
(Nature Publishing Group, 2018)
Apoptosis is a highly regulated form of programmed cell death, essential to the development and homeostasis of multicellular ... |
Artículo
Nuclear cytochrome c – a mitochondrial visitor regulating damaged chromatin dynamics
(Wiley-Blackwell, 2018)
Over the past decade, evidence has emerged suggesting a broader role for cytochrome c (Cyt c) in programmed cell death. ... |
Tesis Doctoral
 Phosphorylation of cytochrome C: functional and structural features
(2017)
Post-translational modifications often modulate protein function. Actually, phosphorylation of cytochrome c occurs in vivo ... |
Artículo
Histone chaperone activity of Arabidopsis thaliana NRP1 is blocked by cytochrome c
(Oxford University Press, 2017)
Higher-order plants and mammals use similar mechanisms to repair and tolerate oxidative DNA damage. Most studies on the ... |
Artículo
Structural basis of mitochondrial dysfunction in response to cytochrome c phosphorylation at tyrosine 48
(National Academy of Sciences, 2017)
Regulation of mitochondrial activity allows cells to adapt to changing conditions and to control oxidative stress, and its ... |
Artículo
RNA Binding Protein Regulation and Cross-Talk in the Control of AU-rich mRNA Fate
(Frontiers Media, 2017)
mRNA metabolism is tightly orchestrated by highly-regulated RNA Binding Proteins (RBPs) that determine mRNA fate, thereby ... |
Artículo
Fluorinated chaperone-ß-cyclodextrin formulations for ß-glucocerebrosidase activity enhancement in neuronopathic Gaucher disease
(American Chemical Society, 2017)
Amphiphilic glycomimetics encompassing a rigid, undistortable nor-tropane skeleton based on 1,6-anhydro-L-idonojirimycin ... |
Tesis Doctoral
Estructura y estabilidad en plastocianinas de cianobacterias
(2016)
ESTRUCTURA Y ESTABILIDAD EN PLASTOCIANINAS DE CIANOBACTERIAS La elucidación de los factores que determinan las diferencias ... |
Artículo
The Dynamics of the Human Leukocyte Antigen Head Domain Modulates Its Recognition by the T-Cell Receptor
(Public Library of Science, 2016)
Generating the immune response requires the discrimination of peptides presented by the human leukocyte antigen complex ... |
Artículo
Dimerization model of the C-terminal RNA Recognition Motif of HuR
(wiley, 2015)
Human antigen R (HuR) is a ubiquitous 32kDa protein comprising three RNA Recognition Motifs (RRMs), whose main function ... |
Artículo
Respiratory complexes III and IV can each bind two molecules of cytochrome c at low ionic strength
(Elsevier, 2015)
The transient interactions of respiratory cytochrome c with complexes III and IV is herein investigated by using heterologous ... |
Artículo
Structural basis for inhibition of the histone chaperone activity of SET/TAF-Iβ by cytochrome c
(National Academy of Sciences, 2015)
Chromatin is pivotal for regulation of the DNA damage process insofar as it influences access to DNA and serves as a DNA ... |
Artículo
A common signalosome for programmed cell death in humans and plants
(Nature Publishing Group, 2014)
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Artículo
The dynamic complex of cytochrome c6 and cytochrome f studied with paramagnetic NMR spectroscopy
(Elsevier B.V., 2014)
The rapid transfer of electrons in the photosynthetic redox chain is achieved by the formation of short-lived complexes ... |
Artículo
Cytochrome c1 exhibits two binding sites for cytochrome c in plants
(Elsevier, 2014)
n plants, channeling of cytochrome c molecules between complexes III and IV has been purported to shuttle electrons within ... |
Artículo
Structural and Functional Analysis of Novel Human Cytochrome c Targets in Apoptosis
(American Society for Biochemistry and Molecular Biology, 2014)
Since the first description of apoptosis four decades ago, great efforts have been made to elucidate, both in vivo and in ... |
Artículo
The C-terminal RNA binding motif of HuR is a multi-functional domain leading to HuR oligomerization and binding to U-rich RNA targets
(Taylor & Francis, 2014)
Human antigen R (HuR) is a 32 kDa protein with 3 RNA Recognition Motifs (RRMs), which bind to Adenylate and uridylate Rich ... |
Artículo
Temperature-driven changeover in the electron-transfer mechanism of a thermophilic plastocyanin
(American Chemical Society, 2014)
Electron-transfer kinetics of the thermophilic protein Plastocyanin fromPhormidium laminosumadsorbed on 1,ω-alkanedithiol ... |
| Artículo |
Artículo
New Arabidopsis thaliana cytochrome c partners: A look into the elusive role of cytochrome c in programmed cell death in plants
(American Society for Biochemistry and Molecular Biology, 2013)
Programmed cell death is an event displayed by many different organisms along the evolutionary scale. In plants, programmed ... |
Artículo
Antimalarial activity of cupredoxins: the interaction of Plasmodium Merozoite Surface Protein 119 (MSP119) and Rusticyanin
(American Society for Biochemistry and Molecular Biology, 2013)
Background: The interaction of MSP119 with the cupredoxin azurin inhibits the growth of Plasmodium falciparum in red blood ... |
Artículo
Yeast ribosomal protein L40 assembles late into precursor 60 S ribosomes and is required for their cytoplasmic maturation
(Elsevier, 2012)
Background: The contribution of ribosomal proteins to ribosome assembly and function is often not well understood. Results: ... |
Artículo
The cytochrome f–plastocyanin complex as a model to study transient interactions between redox proteins
(Wiley, 2012)
Transient complexes, with a lifetime ranging between microseconds and seconds, are essential forbiochemical reactions ... |
Artículo
Voltammetric study of the adsorbed thermophilic plastocyanin from Phormidium laminosum up to 90 °c
(Elsevier, 2012)
Redox thermodynamics and kinetics of plastocyanin from Phormidium laminosum, and of azurin from Pseudonomas aeruginosa, ... |
Artículo
Specific nitration of tyrosines 46 and 48 makes cytochrome c assemble a non-functional apoptosome
(Elsevier, 2012)
Under nitroxidative stress, a minor fraction of cytochrome c can be modified by tyrosine nitration. Here we analyze the ... |
Tesis Doctoral
Análisis Estructural de los Determinantes de la Estabilidad en Plastocianinas
(2011)
La vida se encuentra en casi cualquier lugar de la Tierra, tanto en las grietas hidrotermales de los suelos marinos o en ... |
Artículo
Cytochrome c signalosome in mitochondria
(Springer, 2011)
Cytochrome c delicately tilts the balance between cell life (respiration) and cell death (apoptosis). Whereas cell life ... |
Artículo
How the Local Geometry of the Cu-Binding Site Determines the Thermal Stability of Blue Copper Proteins
(Elsevier, 2011)
Identifying the factors that govern the thermal resistance of cupredoxins is essential for understanding their folding and ... |
Artículo
A structural insight into the C-terminal RNA recognition motifs of T-cell intracellular antigen-1 protein
(Elsevier, 2011)
T-cell intracellular antigen-1 (TIA-1) plays a pleiotropic role in cell homeostasis through the regulation of alternative ... |
Artículo
Modulation of copper site properties by remote residues determines the stability of plastocyanins
(Elsevier, 2010)
The metal cofactor determines the thermal stability in cupredoxins, but how the redox state of copper modulates their ... |
Artículo
Nitration of tyrosine 74 prevents human cytochrome c to play a key role in apoptosis signaling by blocking caspase-9 activation
(Elsevier, 2010)
Tyrosine nitration is one of the most common post-transcriptional modifications of proteins, so affecting their structure ... |
Artículo
Electrostatic strain and concerted motions in the transient complex between plastocyanin and cytochrome f from the cyanobacterium Phormidium laminosum
(Elsevier, 2009)
Many fleeting macromolecular interactions, like those being involved in electron transport, are essential in biology. ... |
Artículo
The atypical iron-coordination geometry of cytochrome f remains unchanged upon binding to plastocyanin, as inferred by XAS
(Springer Verlag, 2006)
The transient complex between cytochrome f and plastocyanin from the cyanobacterium Nostoc sp. PCC 7119 has been analysed ... |
Artículo
Structure of the Complex between Plastocyanin and Cytochrome f from the Cyanobacterium Nostoc sp. PCC 7119 as Determined by Paramagnetic NMR
(Elsevier, 2005)
The complex between cytochrome f and plastocyanin from the cyanobacterium Nostoc has been characterized by NMR spectroscopy. ... |
Artículo
NMR analysis of the transient complex between membrane photosystem I and soluble cytochrome c6
(Elsevier, 2005)
A structural analysis of the surface areas of cytochrome c6, responsible for the transient interaction with photosystem ... |
Tesis Doctoral
Reconocimiento molecular y análisis estructural de complejos transitorios entre proteínas
(2005)
Las interacciones trasitorias entre biomoléculas se han convertido en el centro de la investigación de muchas áreas de la ... |
Artículo
The Interactions of Cyanobacterial Cytochromec6 and Cytochrome f, Characterized by NMR
(Elsevier, 2002)
During oxygenic photosynthesis, cytochromec6 shuttles electrons between the membrane-bound complexes cytochrome bf and ... |
Artículo
An evolutionary analysis of the reaction mechanisms of photosystem I reduction by cytochrome c6 and plastocyanin
(Elsevier, 2002)
Photosystem I reduction by the soluble metalloproteins cytochrome c6 and plastocyanin, which are alternatively synthesized ... |
Artículo
Site-directed Mutagenesis of Cytochromec 6 from Synechocystissp. PCC 6803
(Elsevier, 1999)
This paper reports the first site-directed mutagenesis analysis of any cytochrome c 6, a heme protein that performs the ... |
Artículo
Site-directed Mutagenesis of Cytochromec 6 from Anabaena Species PCC 7119
(Elsevier, 1999)
A number of surface residues of cytochromec 6 from the cyanobacterium Anabaenasp. PCC 7119 have been modified by site-directed ... |
Tesis Doctoral
Transferencia de electrones en el lado oxidante del fotosistema I. Equivalencia funcional entre el citocromo c6 y la plastocianina
(1995)
El presente trabajo forma parte del realizado por el grupo al que el doctorando se encuentra adscrito, en el que se busca ... |