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Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H2O2- and Aβ1-42-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells

 

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Opened Access Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H2O2- and Aβ1-42-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells
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Author: Matos, Ana M. de
Martins, Alice
Man,Teresa
Evans, David
Walter, Magnus
Oliveira, Maria Conceição
López López, Óscar
Fernández-Bolaños Guzmán, José María
Rauter, Amélia P.
Department: Universidad de Sevilla. Departamento de Química orgánica
Date: 2019
Published in: Pharmaceuticals, 12 (2), 98-1-98-18.
Document type: Article
Abstract: With the lack of available drugs able to prevent the progression of Alzheimer’s disease (AD), the discovery of new neuroprotective treatments able to rescue neurons from cell injury is presently a matter of extreme importance and urgency. Here, we w...
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Cite: Matos, A.M.d., Martins, A., Man, e., Evans, D., Walter, M., Oliveira, M.C.,...,Rauter, A.P. (2019). Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H2O2- and Aβ1-42-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells. Pharmaceuticals, 12 (2), 98-1-98-18.
Size: 1.248Mb
Format: PDF

URI: https://hdl.handle.net/11441/88624

DOI: 10.3390/ph12020098

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This work is under a Creative Commons License: 
Attribution-NonCommercial-NoDerivatives 4.0 Internacional

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