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Oncogenic p95HER2/611CTF primes human breast epithelial cells for metabolic stress-induced down-regulation of FLIP and activation of TRAIL-R/Caspase-8-dependent apoptosis

 

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Opened Access Oncogenic p95HER2/611CTF primes human breast epithelial cells for metabolic stress-induced down-regulation of FLIP and activation of TRAIL-R/Caspase-8-dependent apoptosis
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Author: Martín Pérez, Rosa
Yerbes, Rosario
Mora Molina, Rocío
Cano González, Ana María
Arribas, Joaquín
Mazzone, Massimiliano
López Rivas, Abelardo
Palacios, Carmen
Date: 2017
Published in: Oncotarget, 8 (55), 93688-93703.
Document type: Article
Abstract: Oncogenic transformation triggers reprogramming of cell metabolism, as part of the tumorigenic process. However, metabolic reprogramming may also increase the sensitivity of transformed cells to microenvironmental stress, at the early stages of t...
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Cite: Martín Pérez, R., Yerbes, R., Mora Molina, R., Cano González, A.M., Arribas, J., Mazzone, M.,...,Palacios, C. (2017). Oncogenic p95HER2/611CTF primes human breast epithelial cells for metabolic stress-induced down-regulation of FLIP and activation of TRAIL-R/Caspase-8-dependent apoptosis. Oncotarget, 8 (55), 93688-93703.
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URI: https://hdl.handle.net/11441/80929

DOI: 10.18632/oncotarget.21458

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