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Dysfunction of the unfolded protein response increases neurodegeneration in aged rat hippocampus following proteasome inhibition

 

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Opened Access Dysfunction of the unfolded protein response increases neurodegeneration in aged rat hippocampus following proteasome inhibition
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Author: Gavilán, María Paz
Pintado, Cristina
Gavilán Dorronzoro, Elena
Jiménez, Sebastián
Ríos, Rosa M.
Vitorica Ferrández, Francisco Javier
Castaño Navarro, Angélica
Ruano Caballero, Diego
Department: Universidad de Sevilla. Departamento de Bioquímica y Biología Molecular
Date: 2009
Published in: Aging Cell, 8 (6), 654-665.
Document type: Article
Abstract: Dysfunctions of the ubiquitin proteasome system (UPS) have been proposed to be involved in the aetiology and/or progression of several age-related neurodegenerative disorders. However, the mechanisms linking proteasome dysfunction to cell degenerati...
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Cite: Gavilán, M.P., Pintado, C., Gavilán Dorronzoro, E., Jiménez, S., Ríos, R.M., Vitorica Ferrández, F.J.,...,Ruano Caballero, D. (2009). Dysfunction of the unfolded protein response increases neurodegeneration in aged rat hippocampus following proteasome inhibition. Aging Cell, 8 (6), 654-665.
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URI: http://hdl.handle.net/11441/41544

DOI: 10.1111/j.1474-9726.2009.00519.x

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