Browsing Artículos (Bioquímica y Biología Molecular) by Issue Date
Now showing items 1-20 of 177
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Analysis of ceftriaxone and ceftazidime distribution in cerebrospinal fluid of and cerebral extracellular space in awake rats by in vivo microdialysis
(American Society for Microbiology, 1995)In vivo microdialysis was used to estimate the extracellular concentrations of ceftazidime and ceftriaxone, two expanded-spectrum ...
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Effect of oxidative stress, produced by cumene hydroperoxide, on the various steps of protein synthesis. Modifications of elongation factor-2
(American Society for Biochemistry and Molecular Biology, 1996)We have studied the effect of oxidative stress on protein synthesis in rat liver. Cumene hydroperoxide (CH) was used as ...
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Molecular and pharmacological characterization of native cortical γ- aminobutyric acids receptors containing both α1 and α3 subunits
(1996)We have investigated the existence, molecular composition, and benzodiazepine binding properties of native cortical α1-α3 ...
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Article
Obtención y caracterización de aislados proteicos de colza
(1997)Se ha diseñado un proceso de obtención de aislados proteicos a partir de harina de colza desengrasada. El método incluye ...
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Article
Production of an extensive sunflower protein hydrolysate by sequential hydrolysis with endo- and exo-proteases
(1999)Se ha obtenido un aislado proteico de alta calidad a partir de harina desengrasada de girasol, mediante extracción alcalina ...
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GABAa and a-Amino-3-hydroxy-5-methylsoxazole-4-propionate receptors are differentially affected by aging in the rat hippocampus
(American Society for Biochemistry and Molecular Biology, 2000)We have investigated the age-dependent modifications in the expression of eight different subunits of the γ-aminobutyric ...
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Impairment of mineralocorticoid receptor (MR)-dependent biological response by oxidative stress and aging
(American Society for Biochemistry and Molecular Biology, 2002)Acute and chronic treatments of mice with the gluta- thione-depleting agent, L-buthionine-(SR)-sulfoximine (BSO), impaired ...
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Treatment with trkC agonist antibodies delays disease progression in neuromuscular degeneration (nmd) mice
(OXFORD UNIV PRESS, 2005)Spinal muscular atrophy with respiratory distress type 1 (SMARD1) is a fatal autosomal recessive disorder seen in infants. ...
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Article
Vasoactive intestinal peptide induces regulatory dendritic cells with therapeutic effects on autoimmune disorders
(National Academy of Sciences, 2005)The induction of antigen-specific tolerance is critical for the prevention of autoimmunity and maintenance of immune ...
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Article
Oxidative stress is increased in critically ill patients according to antioxidant vitamins intake, independent of severity: A cohort study
(Springer Science + Business Media, 2006)Critically ill patients suffer from oxidative stress caused by reactive oxygen species (ROS) and reactive nitrogen species ...
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Article
Stress Increases Vulnerability to Inflammation in the Rat Prefrontal Cortex
(Society for Neuroscience, 2006)Inflammation could be involved in some neurodegenerative disorders that accompany signs of inflammation. However, because ...
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Article
Mitochondrial toxins and neurodegenerative diseases
(IMR Press, 2007)The selective loss of a particular subset of neurons is a common feature of neurodegenerative disorders. A failure in ...
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Cysteine string protein-α is essential for the high calciumsensitivity of exocytosis in a vertebrate synapse
(Wiley, 2008)Cysteine string protein (CSPa) is a synaptic vesicle protein present in most central and peripheral nervous system ...
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Inflammatory response in the hippocampus of PS1M146L/APP 751SL mouse model of Alzheimer's disease: Age-dependent switch in the microglial phenotype from alternative to classic
(Society for Neuroscience, 2008)Although the microglial activation is concomitant to the Alzheimer's disease, its precise role (neuroprotection vs ...
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Dysfunction of the unfolded protein response increases neurodegeneration in aged rat hippocampus following proteasome inhibition
(Wiley-Blackwell, 2009)Dysfunctions of the ubiquitin proteasome system (UPS) have been proposed to be involved in the aetiology and/or progression ...
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Article
Altered Intracellular Ca2+ Homeostasis in Nerve Terminals of Severe Spinal Muscular Atrophy Mice
(SOC NEUROSCIENCE, 2010)Low levels of survival motor neuron (SMN) protein result in spinal muscular atrophy (SMA), a severe genetic disease ...
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Ciliary neurotrophic factor-induced sprouting preserves motor function in a mouse model of mild spinal muscular atrophy
(OXFORD UNIV PRESS, 2010)Proximal spinal muscular atrophy (SMA) is caused by homozygous loss or mutation of the SMN1 gene on human chromosome 5. ...
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Regional difference in inflammatory response to LPS-injection in the brain: Role of microglia cell density
(Elsevier, 2011)To elucidate whether density of cells could contribute to the extent of microglial activation, we performed in vitro assays ...
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Article
A high redox potential form of cytochrome c550 in photosystem II from Thermosynechococcus elongatus
(American Society for Biochemistry and Molecular Biology Inc., 2011)Cytochrome c550 (cyt c550) is a component of photosystem II (PSII) from cyanobacteria, red algae, and some other eukaryotic ...