idUS - Browsing Artículos (Bioquímica y Biología Molecular) by Issue Date

Article

Inflammatory animal model for parkinson’s disease: the intranigral injection of LPS induced the inflammatory process along with the selective degeneration of nigrostriatal dopaminergic neurons

Machado Quintana, Alberto; Herrera Carmona, Antonio José; Venero Recio, José Luis; Santiago Pavón, Martiniano; Martínez de Pablos, Rocío; Espinosa Oliva, Ana María; Argüelles Castilla, Sandro; Sarmiento Soto, Manuel; Delgado Cortés, M.J.; Mauriño, R.; Cano, Josefina (A. Conti and A. Lewen, 2011)

We have developed an animal model of degeneration of the nigrostriatal dopaminergic neurons, the neuronal system involved in ...

Article

How the Local Geometry of the Cu-Binding Site Determines the Thermal Stability of Blue Copper Proteins

Chaboy, Jesús; Díaz Moreno, Sofía; Díaz Moreno, Irene; Rosa Acosta, Miguel Ángel de la; Díaz Quintana, Antonio Jesús (Elsevier, 2011-01)

Identifying the factors that govern the thermal resistance of cupredoxins is essential for understanding their folding and ...

Article

Metformin inhibits glutaminase activity and protects against hepatic encephalopathy

Bautista Palomas, Juan Dionisio; Campo Castillo, José Antonio del; Romero Gómez, Manuel; Ranchal Illescas, Isidora; Camacho Benítez, Inés; Nuñez Hospital, David; Díaz Herrero, María del Mar; Rojas, Ángela; Maraver Zamora, Marta; Ampuero Herrojo, Javier; Figueruela, Blanca (2012)

Aim: To investigate the influence of metformin use on liver dysfunction and hepatic encephalopathy in a retrospective ...

Article

Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus

Gutiérrez Pérez, Antonia; Vitorica Ferrández, Francisco Javier; Dávila Cansino, José Carlos; Vizuete Chacón, María Luisa; Carmona Cuenca, Irene; Jiménez Muñoz, Sebastián; Trujillo Estrada, Laura Isabel; Sánchez Varo, Raquel María; Torres Canalejo, Manuel; Sánchez Mejías, Elisabeth; Navarro Garrido, Victoria (2012)

Background: Axonal pathology might constitute one of the earliest manifestations of Alzheimer disease. Axonal dystrophies ...

Article

Lipopolysacharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition in rat hippocampus

Ríos Sánchez, Rosa María; Ruano Caballero, Diego; Vitorica Ferrández, Francisco Javier; Pintado Losa, Cristina; Gavilán Dorronzoro, Elena; García Cuervo, Luisa; Castaño Navarro, Angélica; Gutiérrez Pérez, Antonia; Gavilán Dorronzoro, María de la Paz (2012)

Article

Potential use of adipose tissue stem cells in the control of aging

Muñoz Pinto, Mario Faustino; Zurita Díaz, Francisco; Argüelles Castilla, Sandro; Vázquez, Rocío; Serres, José; Guzmán Chozas, Matías; Guillén Sanz, Remedios; Rodríguez Gómez, José Antonio; Cortés, José Luis; Muñoz Franco, Jaime; Pintor Toro, José Antonio; Cano Rodríguez, María Mercedes; Ayala Gómez, Antonio (Federation of Anti-Aging Medicine Societies, 2012)

Cell therapy with adult stem cells is a new battle front for the control of aging. Before being used for this purpose, we ...

Article

Folic acid supplementation: some practical aspects

Cano Rodríguez, María Mercedes; Muñoz Pinto, Mario Faustino; Ayala Gómez, Antonio; Argüelles Castilla, Sandro (Federation of Anti-Aging Medicine Societies, 2012)

Since 1956, when Harman first postulated the free radical theory of aging, numerous studies have been carried out to test ...

Article

Transcription of Liver X Receptor Is Down-Regulated by 15-Deoxy-Δ12,14-Prostaglandin J2 through Oxidative Stress in Human Neutrophils

Alba Jiménez, Gonzalo; Reyes Quiroz, María Edith; Santa-María Pérez, Consuelo; Ramírez, Remedios; Geniz, Isabel; Jiménez Carrasco, Juan; Martín Nieto, José; Pintado Sanjuán, Elizabeth; Sobrino Beneyto, Francisco (Public Library of Science, 2012)

Liver X receptors (LXRs) are ligand-activated transcription factors of the nuclear receptor superfamily. They play ...

Article

Hyperammonemia induced oxidative stress in cirrhotic rats without promoting differential protein expression in the brain cortex: A 2D-DIGE analysis. In press

Cremades de Molina, Olga; Campo, José Antonio del; Díaz Herrero, María del Mar; Carbonero Aguilar, María del Pilar; Bautista Palomas, Juan Dionisio (2012)

Article

Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus

Sánchez Varo, Raquel María; Trujillo Estrada, Laura Isabel; Sánchez Mejías, Elisabeth; Torres Canalejo, Manuel; Baglietto Vargas, David; Moreno González, Inés; Jiménez Muñoz, Sebastián; Ruano Caballero, Diego; Vizuete Chacón, María Luisa; Vitorica Ferrández, Francisco Javier; Gutiérrez Pérez, Antonia (Springer, 2012)

Dystrophic neurites associated with amyloid plaques precede neuronal death and manifest early in Alzheimer’s disease ...

Article

Elongation factor 2-diphthamide is critical for translation of two IRES-dependent protein targets, XIAP and FGF2, under oxidative stress conditions

Argüelles Castilla, Sandro; Camandola, Simonetta; Cutler, Roy G.; Ayala Gómez, Antonio (Elsevier, 2013)

Elongation factor-2 (eEF2) catalyzes the movement of the ribosome along the mRNA. A single histidine residue in eEF2 (H715) ...

Article

Molecular Control of the Amount, Subcellular Location and Activity State of Translation Elongation Factor 2 (eEF-2) in Neurons Experiencing Stress

Argüelles Castilla, Sandro; Camandola, Simonetta; Hutchison, Emmette R.; Cutler, Roy G.; Ayala Gómez, Antonio (Eslsevier, 2013)

Eukaryotic elongation factor 2 (eEF-2) is an important regulator of the protein translation machinery wherein it controls ...

Article

GSK-3β signaling determines autophagy activation in the breast tumor cell line MCF7 and inclusion formation in the non-tumor cell line MCF10A in response to proteasome inhibition

Gavilán Dorronzoro, Elena; Sánchez Aguayo, Inmaculada; Daza Navarro, María Paula; Ruano Caballero, Diego (2013)

Article

Glutaredoxins are essential for stress adaptation in the cyanobacterium Synechocystis sp. PCC 6803

Sánchez Riego, Ana María; López Maury, Luis; Florencio Bellido, Francisco Javier (Frontiers media, 2013)

Glutaredoxins are small redox proteins able to reduce disulfides and mixed disulfides between GSH and proteins. Synechocystis ...

Article

In vivo modification of Abeta plaque toxicity as a novel neuroprotective lithium-mediated therapy for Alzheimer’s disease pathology

Trujillo Estrada, Laura Isabel; Jiménez Muñoz, Sebastián; Castro, Vanessa de; Torres Canalejo, Manuel; Baglietto Vargas, David; Moreno González, Inés; Navarro Garrido, Victoria; Sánchez Varo, Raquel María; Sánchez Mejías, Elisabeth; Dávila Cansino, José Carlos; Vizuete Chacón, María Luisa; Gutiérrez Pérez, Antonia; Vitorica Ferrández, Francisco Javier (BioMed Central, 2013)

Background: Alzheimer’s disease (AD) is characterized by the abnormal accumulation of extracellular beta-amyloid (Abeta) ...

Article

Protección antioxidante de un extracto enzimático de orujo de la uva y sus polifenoles mayoritarios sobre la activación de NADPH oxidasa y la inhibición de superóxido dismutasa

Pérez Ternero, Cristina; Rodríguez Rodríguez, Rosalía; Parrado Rubio, Juan; Herrera González, María Dolores; Álvarez de Sotomayor Paz, María (Sociedad Española de Farmacología: Fundación Teófilo Hernando, 2013)

Article

1–42 b -Amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death

Manterola, L.; Hernando Rodríguez, M.; Ruiz, A.; Jiménez Muñoz, Sebastián (Nature Publishing Group, 2013)

1–42 b -Amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death L Manterola 1,12 , M Hernando-Rodr ı ...

Article

Stress and inflammation: a detrimental combination in the development of neurodegenerative disease

Martínez de Pablos, Rocío; Espinosa Oliva, Ana María; Sarmiento Soto, Manuel; Venero Recio, José Luis (Smart Science and Technology, 2014)

Chronic stress accelerates the appearance of some neurodegenerative disorders, such as Alzheimer’s disease and Parkinson´s ...

Article

Diseño y escalado de un proceso biotecnológico de valorización de suero lácteo mediante la producción de ácido láctico

Caballero Jiménez, Pablo; Rodríguez Morgado, Bruno; Parrado Rubio, Juan (Universidad Pablo de Olavide, 2014)

Motivación: La industria quesera genera grandes cantidades de suero lácteo, líquido que queda tras la separación de la ...

Article

Lipid peroxidation: Production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal

Ayala Gómez, Antonio; Muñoz Pinto, Mario Faustino; Argüelles Castilla, Sandro (Hindawi Publishing Corporation, 2014)

Lipid peroxidation can be described generally as a process under which oxidants such as free radicals attack lipids ...

Browsing Artículos (Bioquímica y Biología Molecular) by Issue Date

Inflammatory animal model for parkinson’s disease: the intranigral injection of LPS induced the inflammatory process along with the selective degeneration of nigrostriatal dopaminergic neurons ﻿

How the Local Geometry of the Cu-Binding Site Determines the Thermal Stability of Blue Copper Proteins ﻿

Metformin inhibits glutaminase activity and protects against hepatic encephalopathy ﻿

Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus ﻿

Lipopolysacharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition in rat hippocampus ﻿

Potential use of adipose tissue stem cells in the control of aging ﻿

Folic acid supplementation: some practical aspects ﻿

Transcription of Liver X Receptor Is Down-Regulated by 15-Deoxy-Δ12,14-Prostaglandin J2 through Oxidative Stress in Human Neutrophils ﻿

Hyperammonemia induced oxidative stress in cirrhotic rats without promoting differential protein expression in the brain cortex: A 2D-DIGE analysis. In press ﻿

Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus ﻿

Elongation factor 2-diphthamide is critical for translation of two IRES-dependent protein targets, XIAP and FGF2, under oxidative stress conditions ﻿

Molecular Control of the Amount, Subcellular Location and Activity State of Translation Elongation Factor 2 (eEF-2) in Neurons Experiencing Stress ﻿

GSK-3β signaling determines autophagy activation in the breast tumor cell line MCF7 and inclusion formation in the non-tumor cell line MCF10A in response to proteasome inhibition ﻿

Glutaredoxins are essential for stress adaptation in the cyanobacterium Synechocystis sp. PCC 6803 ﻿

In vivo modification of Abeta plaque toxicity as a novel neuroprotective lithium-mediated therapy for Alzheimer’s disease pathology ﻿

Protección antioxidante de un extracto enzimático de orujo de la uva y sus polifenoles mayoritarios sobre la activación de NADPH oxidasa y la inhibición de superóxido dismutasa ﻿

1–42 b -Amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death ﻿

Stress and inflammation: a detrimental combination in the development of neurodegenerative disease ﻿

Diseño y escalado de un proceso biotecnológico de valorización de suero lácteo mediante la producción de ácido láctico ﻿

Lipid peroxidation: Production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal ﻿

Inflammatory animal model for parkinson’s disease: the intranigral injection of LPS induced the inflammatory process along with the selective degeneration of nigrostriatal dopaminergic neurons

How the Local Geometry of the Cu-Binding Site Determines the Thermal Stability of Blue Copper Proteins

Metformin inhibits glutaminase activity and protects against hepatic encephalopathy

Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus

Lipopolysacharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition in rat hippocampus

Potential use of adipose tissue stem cells in the control of aging

Folic acid supplementation: some practical aspects

Transcription of Liver X Receptor Is Down-Regulated by 15-Deoxy-Δ12,14-Prostaglandin J2 through Oxidative Stress in Human Neutrophils

Hyperammonemia induced oxidative stress in cirrhotic rats without promoting differential protein expression in the brain cortex: A 2D-DIGE analysis. In press

Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus

Elongation factor 2-diphthamide is critical for translation of two IRES-dependent protein targets, XIAP and FGF2, under oxidative stress conditions

Molecular Control of the Amount, Subcellular Location and Activity State of Translation Elongation Factor 2 (eEF-2) in Neurons Experiencing Stress

GSK-3β signaling determines autophagy activation in the breast tumor cell line MCF7 and inclusion formation in the non-tumor cell line MCF10A in response to proteasome inhibition

Glutaredoxins are essential for stress adaptation in the cyanobacterium Synechocystis sp. PCC 6803

In vivo modification of Abeta plaque toxicity as a novel neuroprotective lithium-mediated therapy for Alzheimer’s disease pathology

Protección antioxidante de un extracto enzimático de orujo de la uva y sus polifenoles mayoritarios sobre la activación de NADPH oxidasa y la inhibición de superóxido dismutasa

1–42 b -Amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death

Stress and inflammation: a detrimental combination in the development of neurodegenerative disease

Diseño y escalado de un proceso biotecnológico de valorización de suero lácteo mediante la producción de ácido láctico

Lipid peroxidation: Production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal