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Inflammatory animal model for parkinson’s disease: the intranigral injection of LPS induced the inflammatory process along with the selective degeneration of nigrostriatal dopaminergic neurons

 

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Opened Access Inflammatory animal model for parkinson’s disease: the intranigral injection of LPS induced the inflammatory process along with the selective degeneration of nigrostriatal dopaminergic neurons
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Author: Machado Quintana, Alberto
Herrera Carmona, Antonio José
Venero Recio, José Luis
Santiago Pavón, Martiniano
Martínez de Pablos, Rocío
Espinosa Oliva, Ana María
Argüelles, Sandro
Sarmiento, M.
Delgado Cortés, M.J.
Mauriño, R.
Cano, Josefina
Department: Universidad de Sevilla. Departamento de Bioquímica y Biología Molecular
Date: 2011
Published in: ISRN Neurology
Document type: Article
Abstract: We have developed an animal model of degeneration of the nigrostriatal dopaminergic neurons, the neuronal system involved in Parkinson’s disease (PD). The implication of neuroinflammat ion on this disease was originally established in 1988, when t...
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Cite: Machado de la Quintana, A., Herrera Carmona, A.J., Venero Recio, J.L., Santiago Pavón, M., Martínez de Pablos, R., Espinosa Oliva, A.M.,...,Cano, J. (2011). Inflammatory animal model for parkinson’s disease: the intranigral injection of LPS induced the inflammatory process along with the selective degeneration of nigrostriatal dopaminergic neurons. ISRN Neurology
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URI: http://hdl.handle.net/11441/41537

DOI: http://dx.doi.org/10.5402/2011/476158

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