Author profile: Venero Recio, José Luis
Data
| Name | Venero Recio, José Luis |
| Department | Bioquímica y Biología Molecular |
| Knowledge area | Bioquímica y Biología Molecular |
| Professional category | Catedrático de Universidad |
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Article
 Gal3 Plays a Deleterious Role in a Mouse Model of Endotoxemia
(Multidisciplinary Digital Publishing Institute (MDPI), 2022-01-01)
Lipopolysaccharide (LPS)-induced endotoxemia induces an acute systemic inflammatory response that mimics some important ... |
Article
The Absence of Caspase-8 in the Dopaminergic System Leads to Mild Autism-like Behavior
(Frontiers Media S.A., 2022-01-01)
In the last decade, new non-apoptotic roles have been ascribed to apoptotic caspases. This family of proteins plays an ... |
Article
Arginine deprivation alters microglial polarity and synergizes with radiation to eradicate non-arginine-auxotrophic glioblastoma tumors
(American Society for Clinical Investigation, 2022-01-01)
New approaches for the management of glioblastoma (GBM) are an urgent and unmet clinical need. Here, we illustrate that the ... |
Article
Galectin-3, a rising star in modulating microglia activation under conditions of neurodegeneration
(Springer Nature, 2022-01-01)
The advent of high-throughput single-cell transcriptomic analysis of microglia has revealed different phenotypes that are ... |
Article
The Other Side of SARS-CoV-2 Infection: Neurological Sequelae in Patients
(Frontiers Media S.A., 2021-01-01)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread around the globe causing coronavirus disease ... |
Final Degree Project
Apoe y enfermedad de Alzheimer
(2021-01-01)
La Enfermedad de Alzheimer (EA) es una enfermedad neurodegenerativa que afecta a un creciente número de personas en todo ... |
Article
Galectin-3 Deletion Reduces LPS and Acute Colitis-Induced Pro-Inflammatory Microglial Activation in the Ventral Mesencephalon
(Frontiers Media, 2021-01-01)
Parkinson’s disease is a highly prevalent neurological disorder for which there is currently no cure. Therefore, the ... |
PhD Thesis
Implicación de las caspasas-3 y -8 en el trastorno del espectro autista y la enfermedad de Parkinson
(2020-03-06)
El trastorno del espectro autista (TEA) y la enfermedad de Parkinson (EP) son dos desórdenes neurológicos que presentan ... |
Article
Hydroxytyrosol Decreases LPS- and α-Synuclein-Induced Microglial Activation In Vitro
(MDPI, 2020-01-01)
Neuroinflammation is a common feature shared by neurodegenerative disorders, such as ... |
Article
Microglia: Agents of the CNS Pro-Inflammatory Response
(Multidisciplinary Digital Publishing Institute (MDPI), 2020-01-01)
The pro-inflammatory immune response driven by microglia is a key contributor to the pathogenesis of several neurodegenerative ... |
Article
The Ubiquitin Proteasome System in Neuromuscular Disorders: Moving Beyond Movement
(Multidisciplinary Digital Publishing Institute (MDPI), 2020-01-01)
Neuromuscular disorders (NMDs) affect 1 in 3000 people worldwide. There are more than 150 different types of NMDs, where ... |
Article
Hyperinflammation and Fibrosis in Severe COVID-19 Patients: Galectin-3, a Target Molecule to Consider
(Frontiers Media, 2020-01-01)
COVID-19 disease have become so far the most important sanitary crisis in the XXI century. In light of the events, any ... |
PhD Thesis
The role of Galectin-3 in the pathogenesis of Parkinson's Disease
(2019-12-20)
En 1817, James Parkinson describió por primera vez un conjunto de síntomas motores en el ensayo titulado “Shaking Palsy” ... |
Final Degree Project
Papel de la microglía en la patogenia de enfermedades neurodegenerativas
(2019-07-01)
La microglía son las células del sistema nervioso central encargadas del mantenimiento de la inmunidad ... |
Final Degree Project
Papel de la microglía en la enfermedad de Alzheimer
(2019-06-01)
Microglia have always been thought as the central nervous system security guard. Their functions as sensor, housekeeper ... |
Article
Reformulating Pro-Oxidant Microglia in Neurodegeneration
(MDPI, 2019-01-01)
In neurodegenerative diseases, microglia-mediated neuroinflammation and oxidative stress are central events. Recent ... |
Article
TET2 Regulates the Neuroinflammatory Response in Microglia
(Elsevier, 2019-01-01)
Epigenomic mechanisms regulate distinct aspects of the inflammatory response in immune cells. Despite the central role for ... |
Article
Microglial subtypes: diversity within the microglial community
(EMBO Press, 2019-01-01)
Microglia are brain-resident macrophages forming the first active immune barrier in the central nervous system. They fulfill ... |
Article
Magnetofection as a new tool to study microglia biology
(Medknow Publications, 2019-01-01)
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Article
Galectin‑3, a novel endogenous TREM2 ligand, detrimentally regulates infammatory response in Alzheimer’s disease
(Springer, 2019-01-01)
Alzheimer’s disease (AD) is a progressive neurodegenerative disease in which the formation of extracellular aggregates of ... |
PhD Thesis
Papel de la galectina-3 en la respuesta inmune y en la pérdida neuronal asociada a un modelo murino de daño cerebral traumático.
(2018-07-13)
La lesión cerebral traumática (TBI) es actualmente una causa importante de muerte y discapacidad en la sociedad occidental, ... |
Article
RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation
(Springer Nature, 2018-01-01)
In this study, we took advantage of human-induced pluripotent stem cells (hiPSC) and CRISPR/Cas9 technology to investigate ... |
Article
Effective Knockdown of Gene Expression in Primary Microglia With siRNA and Magnetic Nanoparticles Without Cell Death or Inflammation
(Frontiers Media, 2018-01-01)
Microglia, the resident immune cells of the brain, have multiple functions in physiological and pathological conditions, ... |
Article
Divergent Effects of Metformin on an Inflammatory Model of Parkinson’s Disease
(Frontiers Media, 2018-01-01)
The oral antidiabetic drug metformin is known to exhibit anti-inflammatory properties through activation of AMP kinase, ... |
Article
Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson’s Disease
(Frontiers Media, 2018-01-01)
The impact of systemic inflammation in nigral dopaminergic cell loss remains unclear. Here, we have investigated the role ... |
Final Degree Project
Presente y futuro de la inmunoterapia en cáncer
(2017-09-01)
El cáncer es una de las causas principales de muerte en todo el mundo. La falta de tratamientos en la actualidad, se debe ... |
Article
Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration
(Nature, 2017-01-01)
Traumatic brain injury (TBI) is currently a major cause of morbidity and poor quality of life in Western society, with an ... |
Final Degree Project
Bases moleculares de los inflamasomas: implicaciones patológicas
(2016-01-01)
Esta revisión bibliográfica llevada a cabo, nos acerca hacia varios conceptos relativos a diferentes mecanismos que se ... |
Article
Caspase-8 inhibition represses initial human monocyte activation in septic shock model
(Impact Journals, 2016-01-01)
In septic patients, the onset of septic shock occurs due to the over-activation of monocytes. We tested the therapeutic ... |
Article
Spatio-temporal activation of caspase-8 in myeloid cells upon ischemic stroke
(BioMed Central, 2016-01-01)
Ischemic stroke (caused by thrombosis, embolism or vasoconstriction) lead to the recruitment and activation of immune cells ... |
Article
PGC-1α controls mitochondrial biogenesis and dynamics in lead-induced neurotoxicity. (Erratum) Aging, 2015; 7(9): 629‐647.
(Impact Journals, 2016-01-01)
In this article, the additional author Aine Brigette Henley is added to this manuscript: http://www.impactaging.com/papers/v7/n9/pdf/100790.pdf. |
PhD Thesis
A dual tool. The role of the ripoptosome in phagocytic cell activation and differentiation
(2015-10-19)
El término ripoptosoma hace referencia a la plataforma molecular que contiene, entre otras, dos proteínas implicadas en ... |
Article
PGC-1alfa controls mitochondrial biogenesis and dynamics in lead-induced neurotoxicity
(Impact Journals LLC, 2015-04-09)
Due to its role in regulation of mitochondrial function, PGC1α is emerging as an important player in ageing and neurodegenerative ... |
Article
Relevance of chronic stress and the two faces of microglia in Parkinson’s disease
(rontiers Research Foundation, 2015-01-01)
This review is aimed to highlight the importance of stress and glucocorticoids (GCs) in modulating the ... |
Article
Microglia-secreted galectin-3 acts as a toll-like receptor 4 ligand and contributes to microglial activation
(2015-01-01)
Inflammatory response induced by microglia plays a critical role in the demise of neuronal populations in neuroinflammatory ... |
Article
PGC-1α controls mitochondrial biogenesis and dynamics in lead-induced neurotoxicity
(Impact Journals, 2015-01-01)
Due to its role in regulation of mitochondrial function, PGC1α is emerging as an important player in ageing and neurodegenerative ... |
Article
Deletion of caspase-8 in mouse myeloid cells blocks microglia pro-inflammatory activation and confers protection in MPTP neurodegeneration model
(Impact Journals, LLC, 2015-01-01)
Increasing evidence involves sustained pro-inflammatory microglia activation in the pathogenesis of different neurodegenerative ... |
Article
Neuromelanin activates proinflammatory microglia through a caspase-8-dependent mechanism
(BioMed Central, 2015-01-01)
Background We have uncovered a caspase-dependent (caspase-8/caspase-3/7) signaling governing microglia activation and ... |
Article
Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia
(Nature Publishing Group, 2014-01-01)
The activation of microglia, resident immune cells of the central nervous system, and inflammation-mediated neurotoxicity ... |
Article
The role of Galectin-3 in α-synuclein-induced microglial activation
(BioMed Central, 2014-01-01)
Background: Parkinson ’ s disease (PD) is the most prevalent neurodegenerative motor disorder. The neuropathology ... |
Article
Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation
(BioMed Central, 2014-01-01)
Background: Parkinson’s disease is an irreversible neurodegenerative disease linked to progressive movement disorders and ... |
Article
Stress and inflammation: a detrimental combination in the development of neurodegenerative disease
(Smart Science and Technology, 2014-01-01)
Chronic stress accelerates the appearance of some neurodegenerative disorders, such as Alzheimer’s disease and Parkinson´s ... |
Article
Peripheral inflammation increases the damage in animal models of nigrostriatal dopaminergic neurodegeneration: Possible implication in parkinson's disease incidence
(Hindawi Publishing Corporation, 2011-01-01)
Inflammatory processes described in Parkinson’s disease (PD) and its animal models appear to be important in the progression of ... |
Article
Inflammatory animal model for parkinson’s disease: the intranigral injection of LPS induced the inflammatory process along with the selective degeneration of nigrostriatal dopaminergic neurons
(A. Conti and A. Lewen, 2011-01-01)
We have developed an animal model of degeneration of the nigrostriatal dopaminergic neurons, the neuronal system involved in ... |
| PhD Thesis |
Article
Fatal levofloxacin failure in treatment of a bacteremic patient infected with Streptococcus pneumoniae with a preexisting parC mutation
(American Society for Microbiology, 2008-01-01)
The fatal outcome of levofloxacin treatment in a patient with bacteremic pneumonia caused by Streptococcus pneumoniae with ... |
Article
Mitochondrial toxins and neurodegenerative diseases
(IMR Press, 2007-01-01)
The selective loss of a particular subset of neurons is a common feature of neurodegenerative disorders. A failure in ... |
Article
Stress Increases Vulnerability to Inflammation in the Rat Prefrontal Cortex
(Society for Neuroscience, 2006-01-01)
Inflammation could be involved in some neurodegenerative disorders that accompany signs of inflammation. However, because ... |
| PhD Thesis |
| PhD Thesis |