Data

NameVenero Recio, José Luis
DepartmentBioquímica y Biología Molecular
Knowledge areaBioquímica y Biología Molecular
Professional categoryCatedrático de Universidad
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  Statistics

  • Items

    50

  • Visits

    8124

  • Downloads

    12191

  Publications

 

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Gal3 Plays a Deleterious Role in a Mouse Model of Endotoxemia

Fernández Martín, Juan Carlos; Espinosa Oliva, Ana María; García Domínguez, Irene; Rosado Sánchez, Isaac; Pacheco, Yolanda M.; Moyano, Rosario; Monterde, José G.; Venero Recio, José Luis; Martínez de Pablos, Rocío (Multidisciplinary Digital Publishing Institute (MDPI), 2022-01-01)
Lipopolysaccharide (LPS)-induced endotoxemia induces an acute systemic inflammatory response that mimics some important ...
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The Absence of Caspase-8 in the Dopaminergic System Leads to Mild Autism-like Behavior

Suárez Pereira, Irene; García Domínguez, Irene; Bravo, L.; Santiago Pavón, Martiniano; García Revilla, Juan; Espinosa Oliva, Ana María; Alonso Bellido, Isabel María; López Martín, César; Pérez Villegas, Eva María; Armengol, J. A.; Berrocoso, E.; Venero Recio, José Luis; Martínez de Pablos, Rocío; Ruiz Laza, Rocío (Frontiers Media S.A., 2022-01-01)
In the last decade, new non-apoptotic roles have been ascribed to apoptotic caspases. This family of proteins plays an ...
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Arginine deprivation alters microglial polarity and synergizes with radiation to eradicate non-arginine-auxotrophic glioblastoma tumors

Hajji, Nabil; García Revilla, Juan; Sarmiento Soto, Manuel; Perryman, Richard; Symington, Jake J.; Quarles, Chad C.; Orta Vázquez, Manuel Luis; Mateos Cordero, Santiago; Venero Recio, José Luis; Syed, Nelofer (American Society for Clinical Investigation, 2022-01-01)
New approaches for the management of glioblastoma (GBM) are an urgent and unmet clinical need. Here, we illustrate that the ...
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Galectin-3, a rising star in modulating microglia activation under conditions of neurodegeneration

García Revilla, Juan; Boza Serrano, Antonio; Espinosa Oliva, Ana María; Sarmiento Soto, Manuel; Deierborg, Tomas; Ruiz Laza, Rocío; Martínez de Pablos, Rocío; Burguillos García, Miguel Ángel; Venero Recio, José Luis (Springer Nature, 2022-01-01)
The advent of high-throughput single-cell transcriptomic analysis of microglia has revealed different phenotypes that are ...
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The Other Side of SARS-CoV-2 Infection: Neurological Sequelae in Patients

Alonso Bellido, Isabel María; Bachiller, Sara; Vázquez, Guillermo; Cruz Hernández, Luis; Martínez, Emilio; Ruiz Mateos, Ezequiel; Deierborg, Tomas; Venero Recio, José Luis; Real, Luis Miguel; Ruiz Laza, Rocío (Frontiers Media S.A., 2021-01-01)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread around the globe causing coronavirus disease ...
Final Degree Project
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Apoe y enfermedad de Alzheimer

Venero Recio, José Luis; Rueda Solís, María (2021-01-01)
La Enfermedad de Alzheimer (EA) es una enfermedad neurodegenerativa que afecta a un creciente número de personas en todo ...
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Galectin-3 Deletion Reduces LPS and Acute Colitis-Induced Pro-Inflammatory Microglial Activation in the Ventral Mesencephalon

Espinosa Oliva, Ana María; García Miranda, Pablo; Alonso Bellido, Isabel María; Carvajal Vázquez, Ana Eloisa; González Rodríguez, Melania; Carrillo Jiménez, Alejandro; García Domínguez, Irene; Vázquez Carretero, María Dolores; García Revilla, Juan; Santiago Pavón, Martiniano; Peral Rubio, María José; Venero Recio, José Luis; Martínez de Pablos, Rocío (Frontiers Media, 2021-01-01)
Parkinson’s disease is a highly prevalent neurological disorder for which there is currently no cure. Therefore, the ...
PhD Thesis
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Implicación de las caspasas-3 y -8 en el trastorno del espectro autista y la enfermedad de Parkinson

Venero Recio, José Luis; Martínez de Pablos, Rocío; García Domínguez, Irene (2020-03-06)
El trastorno del espectro autista (TEA) y la enfermedad de Parkinson (EP) son dos desórdenes neurológicos que presentan ...
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Hydroxytyrosol Decreases LPS- and α-Synuclein-Induced Microglial Activation In Vitro

Gallardo Fernández, Marta; Hornedo Ortega, Ruth; Alonso Bellido, Isabel María; Rodríguez Gómez, José Antonio; Troncoso González, Ana María; García Parrilla, María del Carmen; Venero Recio, José Luis; Espinosa Oliva, Ana María; Martínez de Pablos, Rocío (MDPI, 2020-01-01)
Neuroinflammation is a common feature shared by neurodegenerative disorders, such as ...
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Microglia: Agents of the CNS Pro-Inflammatory Response

Rodríguez Gómez, José Antonio; Kavanagh, Edel T.; Engskog-Vlachos, Pinelopi; Engskog, Mikael; Herrera Carmona, Antonio José; Espinosa Oliva, Ana María; Joseph, Bertrand; Hajji, Nabil; Venero Recio, José Luis; Burguillos García, Miguel Ángel (Multidisciplinary Digital Publishing Institute (MDPI), 2020-01-01)
The pro-inflammatory immune response driven by microglia is a key contributor to the pathogenesis of several neurodegenerative ...
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The Ubiquitin Proteasome System in Neuromuscular Disorders: Moving Beyond Movement

Bachiller, Sara; Alonso Bellido, Isabel María; Real, Luis Miguel; Pérez Villegas, Eva María; Venero Recio, José Luis; Deierborg, Tomas; Armengol, José Ángel; Ruiz Laza, Rocío (Multidisciplinary Digital Publishing Institute (MDPI), 2020-01-01)
Neuromuscular disorders (NMDs) affect 1 in 3000 people worldwide. There are more than 150 different types of NMDs, where ...
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Hyperinflammation and Fibrosis in Severe COVID-19 Patients: Galectin-3, a Target Molecule to Consider

García Revilla, Juan; Deierborg, Tomas; Venero Recio, José Luis; Boza Serrano, Antonio (Frontiers Media, 2020-01-01)
COVID-19 disease have become so far the most important sanitary crisis in the XXI century. In light of the events, any ...
PhD Thesis
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The role of Galectin-3 in the pathogenesis of Parkinson's Disease

Deierborg, Tomas; Venero Recio, José Luis; García Revilla, Juan (2019-12-20)
En 1817, James Parkinson describió por primera vez un conjunto de síntomas motores en el ensayo titulado “Shaking Palsy” ...
Final Degree Project
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Papel de la microglía en la patogenia de enfermedades neurodegenerativas

Venero Recio, José Luis; Hernández González, Sara (2019-07-01)
La microglía son las células del sistema nervioso central encargadas del mantenimiento de la inmunidad ...
Final Degree Project
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Papel de la microglía en la enfermedad de Alzheimer

Venero Recio, José Luis; Espina Lozano, Juan Miguel (2019-06-01)
Microglia have always been thought as the central nervous system security guard. Their functions as sensor, housekeeper ...
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Reformulating Pro-Oxidant Microglia in Neurodegeneration

García Revilla, Juan; Alonso Bellido, Isabel María; Burguillos García, Miguel Ángel; Herrera Carmona, Antonio José; Espinosa Oliva, Ana María; Ruiz Laza, Rocío; Cruz Hernández, Luis; García Domínguez, Irene; Roca Ceballos, María Angustias; Santiago Pavón, Martiniano; Rodríguez Gómez, José Antonio; Sarmiento Soto, Manuel; Martínez de Pablos, Rocío; Venero Recio, José Luis (MDPI, 2019-01-01)
In neurodegenerative diseases, microglia-mediated neuroinflammation and oxidative stress are central events. Recent ...
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TET2 Regulates the Neuroinflammatory Response in Microglia

Carrillo Jiménez, Alejandro; Ruiz Laza, Rocío; García Domínguez, Irene; García Revilla, Juan; Espinosa Oliva, Ana María; Venero Recio, José Luis; Burguillos García, Miguel Ángel; Tayara, Khadija (Elsevier, 2019-01-01)
Epigenomic mechanisms regulate distinct aspects of the inflammatory response in immune cells. Despite the central role for ...
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Microglial subtypes: diversity within the microglial community

Venero Recio, José Luis; Stratoulias, Vassilis; Tremblay, Marie-Ève; Joseph, Bertrand (EMBO Press, 2019-01-01)
Microglia are brain-resident macrophages forming the first active immune barrier in the central nervous system. They fulfill ...
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Magnetofection as a new tool to study microglia biology

Venero Recio, José Luis; Burguillos García, Miguel Ángel (Medknow Publications, 2019-01-01)
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Galectin‑3, a novel endogenous TREM2 ligand, detrimentally regulates infammatory response in Alzheimer’s disease

Boza Serrano, Antonio; Ruíz Laza, Rocio; Sánchez Varo, Raquel María; García Revilla, Juan; Yang, Yiyi; Jiménez Ferrer, Itzia; Jiménez Muñoz, Sebastián; Roca Ceballos, María Angustias; Navarro Garrido, Victoria; Vitorica Ferrández, Francisco Javier; Venero Recio, José Luis; Deierborg, Tomas (Springer, 2019-01-01)
Alzheimer’s disease (AD) is a progressive neurodegenerative disease in which the formation of extracellular aggregates of ...
PhD Thesis
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Papel de la galectina-3 en la respuesta inmune y en la pérdida neuronal asociada a un modelo murino de daño cerebral traumático.

Burguillos García, Miguel Ángel; Venero Recio, José Luis; Carrillo Jiménez, Alejandro (2018-07-13)
La lesión cerebral traumática (TBI) es actualmente una causa importante de muerte y discapacidad en la sociedad occidental, ...
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RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation

Buchrieser, Julian; Oliva Martín, María José; Moore, Michael D.; Long, Joshua C. D.; Cowley, Sally A.; Long, Joshua C. D.; Pérez Simón, José Antonio; Venero Recio, José Luis (Springer Nature, 2018-01-01)
In this study, we took advantage of human-induced pluripotent stem cells (hiPSC) and CRISPR/Cas9 technology to investigate ...
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Effective Knockdown of Gene Expression in Primary Microglia With siRNA and Magnetic Nanoparticles Without Cell Death or Inflammation

Carrillo Jiménez, Alejandro; Puigdellívol, Mar; Vilalta, Anna; Venero Recio, José Luis; Brown, Charles Guy; Burguillos García, Miguel Ángel (Frontiers Media, 2018-01-01)
Microglia, the resident immune cells of the brain, have multiple functions in physiological and pathological conditions, ...
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Divergent Effects of Metformin on an Inflammatory Model of Parkinson’s Disease

Tayara, Khadija; Espinosa Oliva, Ana María; García Domínguez, Irene; Ismaiel, Afrah Abdul; Boza Serrano, Antonio; Deierborg, Tomas; Martínez de Pablos, Rocío; Machado de la Quintana, Alberto; Herrera Carmona, Antonio José; Venero Recio, José Luis (Frontiers Media, 2018-01-01)
The oral antidiabetic drug metformin is known to exhibit anti-inflammatory properties through activation of AMP kinase, ...
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Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson’s Disease

García Domínguez, Irene; Veselá, Karolina; García Revilla, Juan; Carrillo Jiménez, Alejandro; Roca Ceballos, María Angustias; Santiago Pavón, Martiniano; Martínez de Pablos, Rocío; Venero Recio, José Luis (Frontiers Media, 2018-01-01)
The impact of systemic inflammation in nigral dopaminergic cell loss remains unclear. Here, we have investigated the role ...
Final Degree Project
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Presente y futuro de la inmunoterapia en cáncer

Venero Recio, José Luis; González Falcón, Carolina (2017-09-01)
El cáncer es una de las causas principales de muerte en todo el mundo. La falta de tratamientos en la actualidad, se debe ...
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Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration

Kei Yip, Ping; Carrillo Jiménez, Alejandro; King, Paul; Vilalta, Anna; Venero Recio, José Luis; Burguillos García, Miguel Ángel (Nature, 2017-01-01)
Traumatic brain injury (TBI) is currently a major cause of morbidity and poor quality of life in Western society, with an ...
Final Degree Project
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Bases moleculares de los inflamasomas: implicaciones patológicas

Venero Recio, José Luis; Pérez Márquez, Carlos (2016-01-01)
Esta revisión bibliográfica llevada a cabo, nos acerca hacia varios conceptos relativos a diferentes mecanismos que se ...
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Caspase-8 inhibition represses initial human monocyte activation in septic shock model

Oliva Martín, María José; Sánchez Abarca, Luis Ignacio; Rodhe, Johanna; Carrillo Jiménez, Alejandro; Vlachos, Pinelopi; Herrera Carmona, Antonio José; García Quintanilla, Alberto; Caballero Velázquez, Teresa; Venero Recio, José Luis (Impact Journals, 2016-01-01)
In septic patients, the onset of septic shock occurs due to the over-activation of monocytes. We tested the therapeutic ...
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Spatio-temporal activation of caspase-8 in myeloid cells upon ischemic stroke

Rodhe, Johanna; Burguillos García, Miguel Ángel; Martínez de Pablos, Rocío; Kavanagh, Edel T.; Persson, Annette; Englund, Elisabet; Venero Recio, José Luis (BioMed Central, 2016-01-01)
Ischemic stroke (caused by thrombosis, embolism or vasoconstriction) lead to the recruitment and activation of immune cells ...
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PGC-1α controls mitochondrial biogenesis and dynamics in lead-induced neurotoxicity. (Erratum) Aging, 2015; 7(9): 629‐647.

Dabrowska, Aleksandra; Venero Recio, José Luis; Iwasawa, Ryota; Hankir, Mohammed‐khair; Rahman, Sunniyat; Brigette Henley, Aine; Boobis, Alan; Hajji, Nabil (Impact Journals, 2016-01-01)
In this article, the additional author Aine Brigette Henley is added to this manuscript: http://www.impactaging.com/papers/v7/n9/pdf/100790.pdf.
PhD Thesis
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A dual tool. The role of the ripoptosome in phagocytic cell activation and differentiation

Venero Recio, José Luis; Burguillos García, Miguel Ángel; Oliva Martín, María José (2015-10-19)
El término ripoptosoma hace referencia a la plataforma molecular que contiene, entre otras, dos proteínas implicadas en ...
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PGC-1alfa controls mitochondrial biogenesis and dynamics in lead-induced neurotoxicity

Dabrowska, Aleksandra; Venero Recio, José Luis; Iwasawa, Ryota; Hankir, Mohammed‐khair; Rahman, Sunniyat; Boobis, Alan; Hajji, Nabil (Impact Journals LLC, 2015-04-09)
Due to its role in regulation of mitochondrial function, PGC1α is emerging as an important player in ageing and neurodegenerative ...
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Relevance of chronic stress and the two faces of microglia in Parkinson’s disease

Herrera Carmona, Antonio José; Espinosa Oliva, Ana María; Carrillo Jiménez, Alejandro; Oliva Martín, María José; García Revilla, Juan; García Quintanilla, Alberto; Martínez de Pablos, Rocío; Venero Recio, José Luis (rontiers Research Foundation, 2015-01-01)
This review is aimed to highlight the importance of stress and glucocorticoids (GCs) in modulating the ...
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Microglia-secreted galectin-3 acts as a toll-like receptor 4 ligand and contributes to microglial activation

Burguillos García, Miguel Ángel; Svensson, Martina; Schulte, Tim; Boza Serrano, Antonio; García Quintanilla, Alberto; Kavanagh, Edel T.; Santiago Pavón, Martiniano; Viceconte, Nikenza; Oliva Martín, María José; Osman, Ahmed Mohamed; Salomonsson, Emma; Amar, Lahouari; Persson, Annette; Blomgren, Klas; Achour, Adnane; Englund, Elisabet; Leffler, Hakon; Venero Recio, José Luis; Joseph, Bertrand; Deierborg, Tomas (2015-01-01)
Inflammatory response induced by microglia plays a critical role in the demise of neuronal populations in neuroinflammatory ...
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PGC-1α controls mitochondrial biogenesis and dynamics in lead-induced neurotoxicity

Dabrowska, Aleksandra; Venero Recio, José Luis; Iwasawa, Ryota; Hankir, Mohammed‐khair; Rahman, Sunniyat; Boobis, Alan (Impact Journals, 2015-01-01)
Due to its role in regulation of mitochondrial function, PGC1α is emerging as an important player in ageing and neurodegenerative ...
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Deletion of caspase-8 in mouse myeloid cells blocks microglia pro-inflammatory activation and confers protection in MPTP neurodegeneration model

Kavanagh, Edel T.; Burguillos García, Miguel Ángel; Carrillo Jiménez, Alejandro; Oliva Martín, María José; Santiago Pavón, Martiniano; Rodhe, Johanna; Joseph, Bertrand; Venero Recio, José Luis (Impact Journals, LLC, 2015-01-01)
Increasing evidence involves sustained pro-inflammatory microglia activation in the pathogenesis of different neurodegenerative ...
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Neuromelanin activates proinflammatory microglia through a caspase-8-dependent mechanism

Viceconte, Nikenza; Burguillos García, Miguel Ángel; Herrera Carmona, Antonio José; Martínez de Pablos, Rocío; Joseph, Bertrand; Venero Recio, José Luis (BioMed Central, 2015-01-01)
Background We have uncovered a caspase-dependent (caspase-8/caspase-3/7) signaling governing microglia activation and ...
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Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia

Kavanagh, Edel T.; Rodhe, Johanna; Burguillos García, Miguel Ángel; Venero Recio, José Luis; Joseph, Bertrand (Nature Publishing Group, 2014-01-01)
The activation of microglia, resident immune cells of the central nervous system, and inflammation-mediated neurotoxicity ...
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The role of Galectin-3 in α-synuclein-induced microglial activation

Boza Serrano, Antonio; Reyes, Juan F.; Rey, Nolwen L.; Leffler, Hakon; Bousset, Luc; Nilsson, Ulf J.; Brundin, Patrik; Venero Recio, José Luis; Burguillos García, Miguel Ángel; Deierborg, Tomas (BioMed Central, 2014-01-01)
Background: Parkinson ’ s disease (PD) is the most prevalent neurodegenerative motor disorder. The neuropathology ...
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Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation

Martínez de Pablos, Rocío; Herrera Carmona, Antonio José; Espinosa Oliva, Ana María; Sarmiento Soto, Manuel; Muñoz Pinto, Mario Faustino; Machado Quintana, Alberto; Venero Recio, José Luis (BioMed Central, 2014-01-01)
Background: Parkinson’s disease is an irreversible neurodegenerative disease linked to progressive movement disorders and ...
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Stress and inflammation: a detrimental combination in the development of neurodegenerative disease

Martínez de Pablos, Rocío; Espinosa Oliva, Ana María; Sarmiento Soto, Manuel; Venero Recio, José Luis (Smart Science and Technology, 2014-01-01)
Chronic stress accelerates the appearance of some neurodegenerative disorders, such as Alzheimer’s disease and Parkinson´s ...
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Peripheral inflammation increases the damage in animal models of nigrostriatal dopaminergic neurodegeneration: Possible implication in parkinson's disease incidence

Machado Quintana, Alberto; Herrera Carmona, Antonio José; Venero Recio, José Luis; Santiago Pavón, Martiniano; Martínez de Pablos, Rocío; Villarán, Ruth; Espinosa Oliva, Ana María; Argüelles Castilla, Sandro; Sarmiento Soto, Manuel; Delgado Cortés, M.J.; Mauricio, R.; Cano, Josefina (Hindawi Publishing Corporation, 2011-01-01)
Inflammatory processes described in Parkinson’s disease (PD) and its animal models appear to be important in the progression of ...
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Inflammatory animal model for parkinson’s disease: the intranigral injection of LPS induced the inflammatory process along with the selective degeneration of nigrostriatal dopaminergic neurons

Machado Quintana, Alberto; Herrera Carmona, Antonio José; Venero Recio, José Luis; Santiago Pavón, Martiniano; Martínez de Pablos, Rocío; Espinosa Oliva, Ana María; Argüelles Castilla, Sandro; Sarmiento Soto, Manuel; Delgado Cortés, M.J.; Mauriño, R.; Cano, Josefina (A. Conti and A. Lewen, 2011-01-01)
We have developed an animal model of degeneration of the nigrostriatal dopaminergic neurons, the neuronal system involved in ...
PhD Thesis
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Biochemical and molecular bases of the cell death in the neuroinflammatory of Parkinson's disease induced by LPS

Venero Recio, José Luis; Burguillos García, Miguel Ángel (2009-01-01)
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Fatal levofloxacin failure in treatment of a bacteremic patient infected with Streptococcus pneumoniae with a preexisting parC mutation

Cueto López, Marina de; Rodríguez Martínez, José Manuel; Soriano Pérez, Manuel Jesús; López Cerero, Lorena; Venero Recio, José Luis; Pascual Hernández, Álvaro (American Society for Microbiology, 2008-01-01)
The fatal outcome of levofloxacin treatment in a patient with bacteremic pneumonia caused by Streptococcus pneumoniae with ...
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Mitochondrial toxins and neurodegenerative diseases

Ayala Gómez, Antonio; Venero Recio, José Luis; Cano, Josefina; Machado, Alberto (IMR Press, 2007-01-01)
The selective loss of a particular subset of neurons is a common feature of neurodegenerative disorders. A failure in ...
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Stress Increases Vulnerability to Inflammation in the Rat Prefrontal Cortex

Martínez de Pablos, Rocío; Fernández Villarán, Ruth; Argüelles Castilla, Sandro; Herrera Carmona, Antonio José; Venero Recio, José Luis; Ayala Gómez, Antonio (Society for Neuroscience, 2006-01-01)
Inflammation could be involved in some neurodegenerative disorders that accompany signs of inflammation. However, because ...
PhD Thesis
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Regulación de la expresión de BDNF en los ganglios basales en distintos modelos de la enfermedad de Huntington

Venero Recio, José Luis; Machado Quintana, Alberto; Rite Zambrano, Inmaculada (2004-01-01)
PhD Thesis