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Epidemiology and Clinical Features of Infections Caused by Extended-Spectrum Beta-Lactamase-Producing Escherichia coli in Nonhospitalized Patients

Opened Access Epidemiology and Clinical Features of Infections Caused by Extended-Spectrum Beta-Lactamase-Producing Escherichia coli in Nonhospitalized Patients

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Autor: Rodríguez-Baño, Jesús
Dolores Navarro, María
Romero, Luisa
Martínez-Martínez, Luis
Muniain Ezcurra, Miguel Angel
Perea J., Evelio
Pérez-Cano, Ramón
Pascual Hernández, Álvaro
Departamento: Universidad de Sevilla. Departamento de Medicina
Universidad de Sevilla. Departamento de Microbiología
Fecha: 2004-03
Publicado en: Journal of Clinical Microbiology, 42(3), 1089–1094
Tipo de documento: Artículo
Resumen: Infections due to extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli (ESBLEC) in nonhospitalize patients seem to be emerging in different countries. Their incidence, epidemiology, and clinical impact in the community have not been studied. We describe the epidemiology and clinical features of infections caused by ESBLEC in nonhospitalized patients in Spain and the results of a case-control study performed to investigate the risk factors associated with the acquisition of these organisms. The clonal relatedness of the organisms was assessed by repetitive extragenic palindromic sequence PCR. The ESBLs and the genes encoding the ESBLs were initially characterized by isoelectric focusing and PCR, respectively. Forty-nine patients (76% with urinary tract infections, 22% with asymptomatic bacteriuria, and 2% with acute cholangitis) were included. Six patients were bacteremic. Diabetes mellitus (odds ratio, 5.5; 95% confidence interval, 1.6 to 18.7), previous fluoroquinolo...
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Tamaño: 96.61Kb
Formato: PDF

URI: http://hdl.handle.net/11441/41127

DOI: http://dx.doi.org/10.1128/jcm.42.3.1089-1094.2004

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