Medicina
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Artículo
The HLA-DQA1*05 genotype does not influence the clinical response to ustekinumab and vedolizumab
(Aran Ediciones S.A., 2023)Background: the success of strategies with earlier anti-TNF drugs for the treatment of inflammatory bowel disease (IBD) ...
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Comparison of the 2022 and 2017 European LeukemiaNet risk classifications in a real-life cohort of the PETHEMA group
(Springer Nature, 2023)Next-Generation Sequencing is needed for the accurate genetic risk stratification of acute myeloid leukemia according to ...
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A phase II, prospective, randomized, open-label study of defibrotide added to standard-of-care prophylaxis for the prevention of acute graft-versus-host disease after allogeneic hematopoietic cell transplantation
(Ferrata Storti Foundation, 2023)Acute graft-versus-host disease (aGvHD) is a life-threatening complication typically occurring within 100 days after ...
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Safe use of proton-pump inhibitors
(Aran Ediciones S.A., 2023)Proton-pump inhibitors (PPIs) are one of the most widely used drug classes worldwide. Their discovery goes back to the ...
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Outcomes after intensive chemotherapy for secondary and myeloid-related changes acute myeloid leukemia patients aged 60 to 75 years old: a retrospective analysis from the PETHEMA registry
(Ferrata Storti Foundation, 2024)Treatment options for patients with secondary acute myeloid leukemia (sAML) and AML with myeloid-related changes (AMLMRC) ...
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Oportunistic diagnosis based on age and hepatitis C virus clearance: an essential step to improve the overall health of the liver
(Aran Ediciones S.A., 2023)Back in January 2022, a The Lancet-European Association for the Study of the Liver (EASL) Commission on the impact of ...
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A phase IIa active-comparator-controlled study to evaluate the efficacy and safety of efinopegdutide in patients with non-alcoholic fatty liver disease
(Elsevier, 2023)Background & Aims: This study assessed the effects of the glucagon-like peptide-1 (GLP-1)/glucagon receptor ...
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Tesis Doctoral
Estudio de las características clínicas e histológicas y del manejo terapéutico del melanoma cutáneo primario en personas mayores en el área de gestión sanitaria sur de Sevilla
(2024-02-02)Introducción: El melanoma cutáneo es un tumor maligno cuya incidencia se ha ido incrementando en las últimas décadas a ...
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Tesis Doctoral
Enfermedad tromboembólica venosa en el paciente oncológico: manejo terapéutico y complicaciones
(2024-02-19)La relación entre la enfermedad tromboembólica venosa (ETV) y el cáncer representa un desafío en la práctica clínica. La ...
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Tesis Doctoral
Efecto de los antidiabéticos análogos del receptor de GLP1 sobre la distensibilidad vascular y la enfermedad cardiovascular en sujetos diabéticos tipo 2
(2024-02-21)Objetivos: analizar el comportamiento de los análogos del receptor de GLP1 (arGLP1) en sujetos diabéticos tras cumplir ...
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Clinical variables impacting on the estimation of utilities in chronic obstructive pulmonary disease
(Dove Medical Press LTD, 2015-02-16)Purpose: Health utilities are widely used in health economics as a measurement of an individual’s preference and show the ...
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Epidemiology and risk factors of mycotic aneurysm in patients with infective endocarditis and the impact of its rupture in outcomes. Analysis of a national prospective cohort
(Oxford Univ Press, 2024)Background. Several aspects of the occurrence and management of mycotic aneurysm (MA) in patients with infective endocarditis ...
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The novel combination of sirolimus and bortezomib prevents graft-versus-host disease but maintains the graft-versus-leukemia effect after allogeneic transplantation
(Ferrata Storti Foundation, 2012)Background We have previously shown that bortezomib induces a depletion of alloreactive T cells and allows the expansion ...
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Reduced intensity conditioning increases risk of severe cGVHD: identification of risk factors for cGVHD in a multicenter setting
(Springer, 2018)Chronic graft-versus-host disease (cGVHD) remains a major cause of morbidity and mortality after allogeneic hematopoietic ...
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Survival Outcomes and Health-Related Quality of Life in Older Adults Diagnosed with Acute Myeloid Leukemia Receiving Frontline Therapy in Daily Practice
(MPDI, 2023-11-28)Acute myeloid leukemia has a poor prognosis in older adults, and its management is often unclear due to its underrepresentation ...
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Impact of disease burden and late loss of B cell aplasia on the risk of relapse after CD19 chimeric antigen receptor T Cell (Tisagenlecleucel) infusion in pediatric and young adult patients with relapse/refractory acute lymphoblastic leukemia: role of B-cell monitoring
(Frontiers Media S.A., 2024-01-16)Introduction: Loss of B-cell aplasia (BCA) is a well-known marker of functional loss of CD19 CAR-T. Most relapses and ...
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Hematological Neoplasms with Eosinophilia
(MDPI, 2024-01-12)The diagnostic assessment of eosinophilias is complex, requiring a multidisciplinary approach and often involving diagnostic ...
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Cannabinoids induce cell death in leukaemic cells through Parthanatos and PARP-related metabolic disruptions
(Nature Publishing Group, 2024)BACKGROUND: Several studies have described a potential anti-tumour effect of cannabinoids (CNB). CNB receptor 2 (CB2) is ...
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Tesis Doctoral
La melatonina como biomarcador de los trastornos del sueño en pacientes con Esclerosis Múltiple
(2023-09-28)Introducción: La EM se trata de una enfermedad inmunológica, inflamatoria desmielinizante y degenerativa del SNC, caracterizada ...
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Tesis Doctoral
Factores de riesgo para el desarrollo de infecciones por enterobacterales productores de carbapenemasas
(2024-01-17)INTRODUCCIÓN La resistencia a los antibióticos entre las bacterias ha sido reconocida como uno de los problemas de salud ...