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Evaluation of toxic effects induced by repeated exposure to Cylindrospermopsin in rats using a 28-day feeding study
(Elsevier, 2021-05)
Cylindrospermopsin (CYN) is a toxin with a world-wide increasing occurrence. It can induce toxic effects both in humans and the environment, and toxicity studies are needed to complete its toxicological profile. In this ...
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Potential use of chemoprotectants against the toxic effects of cyanotoxins: A review
(MDPI, 2017)
Cyanobacterial toxins, particularly microcystins (MCs) and cylindrospermopsin (CYN), are responsible for toxic effects in humans and wildlife. In order to counteract or prevent their toxicity, various strategies have ...
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Cylindrospermopsin-microcystin-LR combinations may induce genotoxic and histopathological damage in rats
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)
Cylindrospermopsin (CYN) and microcystins (MC) are cyanotoxins that can occur simultaneously in contaminated water and food. CYN/MC-LR mixtures previously investigated in vitro showed an induction of micronucleus (MN) ...
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Immunomodulatory Effects of Cylindrospermopsin in Human T Cells and Monocytes
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
Cylindrospermopsin (CYN) is a cyanotoxin with an increasing occurrence, and therefore it is important to elucidate its toxicity profile. CYN has been classified as a cytotoxin, although the scientific literature has already ...
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Immunomodulatory Effects of Pure Cylindrospermopsin in Rats Orally Exposed for 28 Days
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Cylindrospermopsin (CYN) is a ubiquitous cyanotoxin showing increasing incidence worldwide. CYN has been classified as a cytotoxin and, among its toxic effects, its immunotoxicity is scarcely studied. This work investigates ...
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Alteración de biomarcadores de estrés oxidativo en Tilapia (Oreochromis niloticus) expuesta a dosis repetidas de Cilindrospermopsina por diferentes vías de exposición
(Asociación Española de Toxicología, 2013)
: Las cianobacterias tienen capacidad de sintetizar una gran variedad de metabolitos secundarios, identificándose entre ellos la Cilindrospermopsina (CYN), toxina principalmente citotóxica. En general, la exposición a ...
Artículo
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Potential Oestrogenic Effects (Following the OECD Test Guideline 440) and Thyroid Dysfunction Induced by Pure Cyanotoxins (Microcystin-LR, Cylindrospermopsin) in Rats
(Elsevier, 2023)
Potential endocrine-disrupting properties of cyanotoxins, such as microcystin-LR (MC-LR) and cylindrospermopsin (CYN) are of concern due to their increasing occurrence, the scarcity of reports on the topic (particularly ...
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Influence of cooking (microwaving and broiling) on cylindrospermopsin concentration in muscle of nile tilapia (oreochromis niloticus) and characterization of decomposition products
(MDPI, 2017)
Cylindrospermopsin (CYN) has become increasingly important as a freshwater algal toxin, showing cytotoxic effects. This toxin is able to bioaccumulate in freshwater food webs, representing a serious human health problem. ...
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In vivo genotoxicity evaluation of cylindrospermopsin in rats using a combined micronucleus and comet assay
(Elsevier, 2019)
Cylindrospermopsin (CYN) is a potent cyanotoxin recognized as an emerging human threat due to its cytotoxicity and potential carcinogenicity. Although the genotoxicity of CYN has been extensively studied in vitro, limited ...
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Influence of two depuration periods on the activity and transcription of antioxidant enzymes in tilapia exposed to repeated doses of Cylindrospermopsin under laboratory conditions
(MDPI, 2014)
The cyanobacterial toxin Cylindrospermopsin (CYN), a potent protein synthesis inhibitor, is increasingly being found in freshwater bodies infested by cyanobacterial blooms worldwide. Moreover, it has been reported to be ...