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The Mitochondrial SDHD Gene Is Required for Early Embryogenesis, and Its Partial Deficiency Results in Persistent Carotid Body Glomus Cell Activation with Full Responsiveness to Hypoxia

 

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Opened Access The Mitochondrial SDHD Gene Is Required for Early Embryogenesis, and Its Partial Deficiency Results in Persistent Carotid Body Glomus Cell Activation with Full Responsiveness to Hypoxia
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Author: Piruat Palomo, José Ignacio
Óscar Pintado, Carmelo
Ortega Sáenz, Patricia
Roche Molina, Marta
López Barneo, José
Department: Universidad de Sevilla. Departamento de Fisiología Médica y Biofísica
Date: 2004
Published in: Molecular and Cellular Biology, Dec. 2004, p. 10933–10940
Document type: Article
Abstract: The SDHD gene encodes one of the two membrane-anchoring proteins of the succinate dehydrogenase (complex II) of the mitochondrial electron transport chain. This gene has recently been proposed to be involved in oxygen sensing because mutations that ...
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URI: http://hdl.handle.net/11441/17484

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