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Differential impairment of catecholaminergic cell maturation and survival by genetic mitochondrial complex II dysfunction

 

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Opened Access Differential impairment of catecholaminergic cell maturation and survival by genetic mitochondrial complex II dysfunction
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Author: Díaz Castro, Blanca
Pintado, Carmelo Oscar
García Flores, Gloria Paula
López Barneo, José
Piruat Palomo, José Ignacio
Department: Universidad de Sevilla. Departamento de Fisiología Médica y Biofísica
Date: 2012
Published in: Molecular and Cellular Biology (Vol.32, Nº16, p.3347–3357)Molecular and Cellular Biology, 32 (16), 3347-3357.
Document type: Article
Abstract: The SDHD gene (subunit D of succinate dehydrogenase) has been shown to be involved in the generation of paragangliomas and pheochromocytomas. Loss of heterozygosity of the normal allele is necessary for tumor transformation of the affected cells. As...
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URI: http://hdl.handle.net/11441/17474

DOI: 10.1128/MCB.00128-12

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