Listar Artículos (Bioquímica y Biología Molecular) por título
Mostrando ítems 197-216 de 223
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Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma oscillations in Alzheimer’s disease
(2023)Background Alzheimer’s disease (AD) is a progressive multifaceted neurodegenerative disorder for which no disease-modifying ...
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TET2 Regulates the Neuroinflammatory Response in Microglia
(Elsevier, 2019)Epigenomic mechanisms regulate distinct aspects of the inflammatory response in immune cells. Despite the central role for ...
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The Absence of Caspase-8 in the Dopaminergic System Leads to Mild Autism-like Behavior
(Frontiers Media S.A., 2022)In the last decade, new non-apoptotic roles have been ascribed to apoptotic caspases. This family of proteins plays an ...
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The combined partial knockdown of CBS and MPST genes induces inflammation, impairs adipocyte function-related gene expression and disrupts protein persulfidation in human adipocytes
(MDPI, 2022)Recent studies in mice and humans demonstrated the relevance of H2S synthesising enzymes, such as CTH, CBS, and MPST, in ...
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The Emerging Role of Senotherapy in Cancer: A Comprehensive Review
(MDPI, 2023-07-22)Senotherapy, a promising therapeutic strategy, has drawn a lot attention recently due to its potential for combating cancer. ...
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The HERC proteins and the nervous system
(Elsevier, 2021)The HERC protein family is one of three subfamilies of Homologous to E6AP C-terminus (HECT) E3 ubiquitin ligases. Six HERC ...
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The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination
(Impact Journals, 2016)A mutation in the HERC2 gene has been linked to a severe neurodevelopmental disorder with similarities to the Angelman ...
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The human bone marrow harbors a CD45− CD11B+ cell progenitor permitting rapid microglia-like cell derivative approaches
(Wiley-Blackwell, 2021)Microglia, the immune sentinel of the central nervous system (CNS), are generated from yolk sac erythromyeloid progenitors ...
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The Multifarious Role of Microglia in Brain Metastasis
(Frontiers Media, 2018)The immune landscape in brain metastasis is a very heterogeneous framework. Amongst a broad plethora of cells within the ...
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The Neurokinin-1 Receptor Is Essential for the Viability of Human Glioma Cells: A Possible Target for Treating Glioblastoma
(Hindawi, 2022)Background. Glioblastoma or glioma is the most common malignant brain tumor. Patients have a prognosis of approximately ...
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The Other Side of SARS-CoV-2 Infection: Neurological Sequelae in Patients
(Frontiers Media S.A., 2021)The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread around the globe causing coronavirus disease ...
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The role of Galectin-3 in α-synuclein-induced microglial activation
(BioMed Central, 2014)Background: Parkinson ’ s disease (PD) is the most prevalent neurodegenerative motor disorder. The neuropathology ...
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The Ubiquitin Proteasome System in Neuromuscular Disorders: Moving Beyond Movement
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)Neuromuscular disorders (NMDs) affect 1 in 3000 people worldwide. There are more than 150 different types of NMDs, where ...
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Time and dose dependent effects of oxidative stress induced by cumene hydroperoxide in neuronal excitability of rat motor cortex neurons
(Elsevier, 2016-03-01)It has been claimed that oxidative stress and the production of reactive oxygen radicals can contribute to neuron degeneration ...
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Transcription of Liver X Receptor Is Down-Regulated by 15-Deoxy-Δ12,14-Prostaglandin J2 through Oxidative Stress in Human Neutrophils
(Public Library of Science, 2012)Liver X receptors (LXRs) are ligand-activated transcription factors of the nuclear receptor superfamily. They play ...
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Transgenic Mouse Models of Alzheimer’s Disease: An Integrative Analysis
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)Alzheimer’s disease (AD) constitutes the most prominent form of dementia among elderly individuals worldwide. Disease ...
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Treatment with mesenchymal stem cells in an animal model of parkinson´s disease
(Federation of Anti-Aging Medicine Societies, 2015) -
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Treatment with trkC agonist antibodies delays disease progression in neuromuscular degeneration (nmd) mice
(OXFORD UNIV PRESS, 2005)Spinal muscular atrophy with respiratory distress type 1 (SMARD1) is a fatal autosomal recessive disorder seen in infants. ...
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Update on Anti-Inflammatory Molecular Mechanisms Induced by Oleic Acid
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)In 2010, the Mediterranean diet was recognized by UNESCO as an Intangible Cultural Heritage of Humanity. Olive oil is the ...